公开(公告)号：US20180344604A1

公开(公告)日：2018-12-06

申请号：US15777987

申请日：2016-12-09

Applicant: DSM IP ASSETS B.V.

Inventor： Stephanie BOUDON ,  Marc HEIDL ,  Eileen JACKSON

IPC: A61K8/49 ,  A61K8/42

CPC classification number: A61K8/4913 ,  A61K8/42 ,  A61K8/492 ,  A61Q19/08 ,  C07D207/16

Abstract: The present invention relates to novel selective 11-beta-hydroxysteroid dehydrogenase type 1 (11ß-HSD1) inhibitors and the use thereof to prevent age-induced skin structure and function defects.