公开(公告)号：US20190098924A1

公开(公告)日：2019-04-04

申请号：US16086433

申请日：2017-04-03

Applicant: DSM IP Assets B.V.

Inventor： Antonio ESTRELLA ,  Elger FUNDA ,  Zdravka MISIC ,  Christian SCHAEFER ,  Markus Ivo BECK ,  Bernd SCHLEGEL ,  Kai URBAN

IPC: A23L33/105 ,  A23L33/125 ,  A23L29/212 ,  A23P10/28

Abstract: The present invention is directed towards a solid formulation comprising a milled carotenoid, at least one hydrocolloid, a glucose syrup, sucrose and at least one water-soluble antioxidant (preferably sodium ascorbate), wherein the carotenoid is selected from the group consisting of lutein and zeaxanthin and any mixture thereof, wherein the hydrocolloid is selected from the group consisting of modified food starches and any mixtures thereof, and wherein the milled carotenoid has the following particle size distribution: D [3, 2] in the range of from 0.6 to 1.5 μm and D [v, 0.5] in the range of from 1.1 to 3.5 μm, all D values as measured by laser diffraction (Malvern Instruments Ltd, Malvern, UK, Mastersizer 3000) according to the Fraunhofer scattering model. This solid formulation is in form of granules which are used for dietary supplements and pharmaceuticals, such as e.g. multi-vitamin and/or multi-mineral tablets. Surprisingly these tablets show a low compression loss.

公开(公告)号：US20240023589A1

公开(公告)日：2024-01-25

申请号：US18373777

申请日：2023-09-27

Applicant: DSM IP Assets B.V.

Inventor： Antonio ESTRELLA ,  Elger FUNDA ,  Zdravka MISIC ,  Christian SCHAEFER ,  Markus Ivo BECK ,  Bernd SCHLEGEL ,  Kai URBAN

IPC: A23L33/105 ,  A23L29/212 ,  A61K9/16 ,  A61K9/20 ,  A23L29/30 ,  A23P10/28 ,  A23L33/125

CPC classification number: A23L33/105 ,  A23L29/212 ,  A61K9/1623 ,  A61K9/2018 ,  A23L29/30 ,  A23P10/28 ,  A23L33/125 ,  A23V2002/00 ,  A23L33/16

Abstract: Solid formulations include a milled carotenoid, at least one hydrocolloid, a glucose syrup, sucrose and at least one water-soluble antioxidant (preferably sodium ascorbate), wherein the carotenoid is selected from the group consisting of lutein and zeaxanthin and any mixture thereof, wherein the hydrocolloid is selected from the group consisting of modified food starches and any mixtures thereof, and wherein the milled carotenoid has the following particle size distribution:



D [3,2] in the range of from 0.6 to 1.5 μm and D [v, 0.5] in the range of from 1.1 to 3.5 μm, all D values as measured by laser diffraction (Malvern Instruments Ltd, Malvern, UK, Mastersizer 3000) according to the Fraunhofer scattering model. The solid formulation is in form of granules which are used for dietary supplements and pharmaceuticals, such as e.g. multi-vitamin and/or multi-mineral tablets and surprisingly show a low compression loss.