公开(公告)号：US20190098924A1

公开(公告)日：2019-04-04

申请号：US16086433

申请日：2017-04-03

Applicant: DSM IP Assets B.V.

Inventor： Antonio ESTRELLA ,  Elger FUNDA ,  Zdravka MISIC ,  Christian SCHAEFER ,  Markus Ivo BECK ,  Bernd SCHLEGEL ,  Kai URBAN

IPC: A23L33/105 ,  A23L33/125 ,  A23L29/212 ,  A23P10/28

Abstract: The present invention is directed towards a solid formulation comprising a milled carotenoid, at least one hydrocolloid, a glucose syrup, sucrose and at least one water-soluble antioxidant (preferably sodium ascorbate), wherein the carotenoid is selected from the group consisting of lutein and zeaxanthin and any mixture thereof, wherein the hydrocolloid is selected from the group consisting of modified food starches and any mixtures thereof, and wherein the milled carotenoid has the following particle size distribution: D [3, 2] in the range of from 0.6 to 1.5 μm and D [v, 0.5] in the range of from 1.1 to 3.5 μm, all D values as measured by laser diffraction (Malvern Instruments Ltd, Malvern, UK, Mastersizer 3000) according to the Fraunhofer scattering model. This solid formulation is in form of granules which are used for dietary supplements and pharmaceuticals, such as e.g. multi-vitamin and/or multi-mineral tablets. Surprisingly these tablets show a low compression loss.

公开(公告)号：US20230284667A1

公开(公告)日：2023-09-14

申请号：US18199700

申请日：2023-05-19

Applicant: DSM IP Assets B.V.

Inventor： Bernd SCHLEGEL ,  Loni SCHWEIKERT ,  Olivia VIDONI

IPC: A23L33/155 ,  A23L29/10 ,  A23P10/28 ,  A23L29/219 ,  A23L29/25 ,  A23L33/15 ,  A61K8/67 ,  A61K47/36 ,  A61K9/20 ,  A23L33/125

CPC classification number: A23L33/155 ,  A23L29/10 ,  A23L29/219 ,  A23L29/25 ,  A23L33/125 ,  A23L33/15 ,  A23P10/28 ,  A61K8/671 ,  A61K9/2018 ,  A61K47/36 ,  A23V2002/00

Abstract: Solid particles comprising at least one fat-soluble vitamin are provided and exhibit better stability when compressed into tablets.

公开(公告)号：US20180343909A1

公开(公告)日：2018-12-06

申请号：US15775425

申请日：2016-12-09

Applicant: DSM IP ASSETS B.V.

Inventor： Bernd SCHLEGEL ,  Loni SCHWEIKERT ,  Olivia VIDONI

IPC: A23L33/155 ,  A23P10/28 ,  A23L33/125 ,  A23L29/10 ,  A23L29/219 ,  A23L29/25

CPC classification number: A23L33/15 ,  A23L29/10 ,  A23L29/219 ,  A23L29/25 ,  A23P10/28 ,  A23V2002/00 ,  A23V2200/262 ,  A23V2200/30 ,  A23V2250/70

Abstract: The present patent application relates to solid particles comprising at least one fatsoluble vitamin, which are more stable when compressed into tablets.

公开(公告)号：US20220071237A1

公开(公告)日：2022-03-10

申请号：US17529121

申请日：2021-11-17

Applicant: DSM IP Assets B.V.

Inventor： Markus BECK ,  Antonio ESTRELLA ,  Elger FUNDA ,  Andrea HITZFELD ,  Christian SCHAEFER ,  Bernd SCHLEGEL ,  Kai URBAN

IPC: A23L2/58 ,  A23L2/395 ,  A23L29/212 ,  A23L5/44 ,  A23L2/52 ,  A23P10/30

Abstract: Beverages are provided which include a beverage liquid and granules mixed with the beverage liquid The granules include: (i) a milled carotenoid consisting of lutein and/or zeaxanthin, wherein the milled carotenoid has the following particle size distribution: D [3,2] in the range of from 0.6 to 1.5 μm, and D [v, 0.5] in the range of from 1.1 to 3.5 μm, (ii) a matrix material which encapsulates the milled carotenoid and comprises at least one modified food starch, a glucose syrup and sucrose, and (iii) a water-soluble antioxidant, wherein the granules have the following particle size distribution: D [3,2] in the range of from 200 to 300 μm, and D [v, 0.5] in the range of from 220 to 320 μm, and wherein all D values are as measured by laser diffraction according to the Fraunhofer scattering model, and wherein the granules do not include an oil or a gelatin.

公开(公告)号：US20190282483A1

公开(公告)日：2019-09-19

申请号：US16339501

申请日：2017-10-09

Applicant: DSM IP ASSETS B.V.

Inventor： Bernd SCHLEGEL

IPC: A61K8/49 ,  A61K8/04 ,  A61K8/60 ,  A61Q17/04

Abstract: The invention relates to an improved process for the manufacture of nano-sized organic UV absorbers having a mean particle size distribution (Dv50) determined by light scattering of less than 200 nm.

公开(公告)号：US20170143017A1

公开(公告)日：2017-05-25

申请号：US15400689

申请日：2017-01-06

Applicant: DSM IP ASSETS B.V.

Inventor： Gabriela BADOLATO BOENISCH ,  Bernd SCHLEGEL

IPC: A23L5/44 ,  A23D7/005 ,  A23L2/58 ,  A61K8/92 ,  A61K8/02 ,  A61Q19/00 ,  A61K8/31 ,  B01J2/04 ,  A23K20/179

CPC classification number: A23L5/44 ,  A23D7/0056 ,  A23K20/158 ,  A23K20/179 ,  A23K40/10 ,  A23L2/58 ,  A23P10/35 ,  A23V2002/00 ,  A61K8/0241 ,  A61K8/0283 ,  A61K8/31 ,  A61K8/375 ,  A61K8/922 ,  A61K9/1617 ,  A61K9/1664 ,  A61K9/1694 ,  A61K2800/10 ,  A61K2800/41 ,  A61K2800/43 ,  A61K2800/522 ,  A61Q19/00 ,  B01J2/04 ,  A23V2200/224 ,  A23V2200/254 ,  A23V2250/194 ,  A23V2250/211 ,  A23V2250/213

Abstract: The present invention relates to process for producing beadlets comprising at least one carotenoid and matrix material, which comprise wax(es) and/or fat(s) with a melting point of between 40 to 85° C., as well as to the production of such beadlets and to the use of such beadlets in compositions.

公开(公告)号：US20250041260A1

公开(公告)日：2025-02-06

申请号：US18921898

申请日：2024-10-21

Applicant: DSM IP Assets B.V.

Inventor： Jihane ACHKAR ,  Bernd SCHLEGEL ,  Loni SCHWEIKERT ,  Olivia Brigitte VIDONI

IPC: A61K31/23 ,  A23L33/125 ,  A23L33/155 ,  A23P10/28 ,  A61K9/16 ,  A61K31/222

Abstract: Solid particles comprising vitamin A and/or its derivatives which are more stable when compressed into tablets are disclosed.

公开(公告)号：US20240023589A1

公开(公告)日：2024-01-25

申请号：US18373777

申请日：2023-09-27

Applicant: DSM IP Assets B.V.

Inventor： Antonio ESTRELLA ,  Elger FUNDA ,  Zdravka MISIC ,  Christian SCHAEFER ,  Markus Ivo BECK ,  Bernd SCHLEGEL ,  Kai URBAN

IPC: A23L33/105 ,  A23L29/212 ,  A61K9/16 ,  A61K9/20 ,  A23L29/30 ,  A23P10/28 ,  A23L33/125

CPC classification number: A23L33/105 ,  A23L29/212 ,  A61K9/1623 ,  A61K9/2018 ,  A23L29/30 ,  A23P10/28 ,  A23L33/125 ,  A23V2002/00 ,  A23L33/16

Abstract: Solid formulations include a milled carotenoid, at least one hydrocolloid, a glucose syrup, sucrose and at least one water-soluble antioxidant (preferably sodium ascorbate), wherein the carotenoid is selected from the group consisting of lutein and zeaxanthin and any mixture thereof, wherein the hydrocolloid is selected from the group consisting of modified food starches and any mixtures thereof, and wherein the milled carotenoid has the following particle size distribution:



D [3,2] in the range of from 0.6 to 1.5 μm and D [v, 0.5] in the range of from 1.1 to 3.5 μm, all D values as measured by laser diffraction (Malvern Instruments Ltd, Malvern, UK, Mastersizer 3000) according to the Fraunhofer scattering model. The solid formulation is in form of granules which are used for dietary supplements and pharmaceuticals, such as e.g. multi-vitamin and/or multi-mineral tablets and surprisingly show a low compression loss.

公开(公告)号：US20160038436A1

公开(公告)日：2016-02-11

申请号：US14780244

申请日：2014-03-27

Applicant: DSM IP ASSETS B.V.

Inventor： Markus BECK ,  Andrea HITZFELD ,  Bernd SCHLEGEL ,  Christian SCHAEFER

IPC: A61K31/047 ,  A61K9/00 ,  A23L1/00 ,  A61K9/16 ,  A23L1/29 ,  A23L1/30

Abstract: The present invention is related to a powderous composition which comprises lutein and which is used in infant food formulations or premixes for infant food formulations.

Abstract translation: 本发明涉及含有叶黄素的粉末组合物，其用于婴儿食品制剂或婴儿食品配方的预混物。

公开(公告)号：US20200085777A1

公开(公告)日：2020-03-19

申请号：US16613915

申请日：2018-05-17

Applicant: DSM IP Assets B.V.

Inventor： Jihane ACHKAR ,  Bernd SCHLEGEL ,  Loni SCHWEIKERT ,  Olivia Brigitte VIDONI

IPC: A61K31/23 ,  A23L33/155 ,  A23P10/28 ,  A23L33/125 ,  A61K31/222 ,  A61K9/16

Abstract: The present patent application relates to solid particles comprising vitamin A and/or its derivatives, which are more stable when compressed into tablets.