公开(公告)号：US20190090517A1

公开(公告)日：2019-03-28

申请号：US16086458

申请日：2017-04-03

Applicant: DSM IP Assets B.V.

Inventor： Markus BECK ,  Antonio ESTRELLA ,  Elger FUNDA ,  Andrea HITZFELD ,  Christian SCHAEFER ,  Bernd SCHLEGEL ,  Kai URBAN

IPC: A23L2/58 ,  A23L2/395 ,  A23L5/44 ,  A23L29/212

Abstract: The present invention is directed towards the use of granules in beverages, wherein the granules comprise (i) a milled carotenoid selected from the group consisting of lutein and zeaxanthin and any mixture thereof having the following particle size distribution: D [3,2] in the range of from 0.6 to 1.5 μm, and D [v, 0.5] in the range of from 1.1 to 3.5 μm, and (ii) a matrix comprising at least one modified food starch, a glucose syrup and sucrose, (iii) a water-soluble antioxidant, wherein the granules have the following particle size distribution: D [3,2] in the range of from 200 to 300 μm, and D [v, 0.5] in the range of from 220 to 320 μm, all D values as measured by laser diffraction according to the Fraunhofer scattering model, whereby the milled carotenoid is encapsulated by the matrix. The present invention is also directed towards the beverages and the granules as such, as well as to a process for the manufacture of the granules. Preferably the carotenoid is lutein, zeaxanthin or any mixture thereof.

公开(公告)号：US20240023589A1

公开(公告)日：2024-01-25

申请号：US18373777

申请日：2023-09-27

Applicant: DSM IP Assets B.V.

Inventor： Antonio ESTRELLA ,  Elger FUNDA ,  Zdravka MISIC ,  Christian SCHAEFER ,  Markus Ivo BECK ,  Bernd SCHLEGEL ,  Kai URBAN

IPC: A23L33/105 ,  A23L29/212 ,  A61K9/16 ,  A61K9/20 ,  A23L29/30 ,  A23P10/28 ,  A23L33/125

CPC classification number: A23L33/105 ,  A23L29/212 ,  A61K9/1623 ,  A61K9/2018 ,  A23L29/30 ,  A23P10/28 ,  A23L33/125 ,  A23V2002/00 ,  A23L33/16

Abstract: Solid formulations include a milled carotenoid, at least one hydrocolloid, a glucose syrup, sucrose and at least one water-soluble antioxidant (preferably sodium ascorbate), wherein the carotenoid is selected from the group consisting of lutein and zeaxanthin and any mixture thereof, wherein the hydrocolloid is selected from the group consisting of modified food starches and any mixtures thereof, and wherein the milled carotenoid has the following particle size distribution:



D [3,2] in the range of from 0.6 to 1.5 μm and D [v, 0.5] in the range of from 1.1 to 3.5 μm, all D values as measured by laser diffraction (Malvern Instruments Ltd, Malvern, UK, Mastersizer 3000) according to the Fraunhofer scattering model. The solid formulation is in form of granules which are used for dietary supplements and pharmaceuticals, such as e.g. multi-vitamin and/or multi-mineral tablets and surprisingly show a low compression loss.

公开(公告)号：US20220053798A1

公开(公告)日：2022-02-24

申请号：US17298765

申请日：2019-12-03

Applicant: DSM IP Assets B.V.

Inventor： Olivia Brigitte VIDONI ,  Christine GOTHSCHECK ,  Kai URBAN

IPC: A23K20/147 ,  A23K20/158 ,  A23K20/28 ,  A23K50/10 ,  A23K40/35

Abstract: The present invention relates to storage stable adsorbates of 3-nitrooxypropanol and derivatives thereof as well as to the production of such adsorbates.

公开(公告)号：US20240365838A1

公开(公告)日：2024-11-07

申请号：US18684736

申请日：2022-10-07

Applicant: DSM IP ASSETS B.V.

Inventor： Patricia DRYJA ,  Kai URBAN ,  Tony STEINEBRUNNER ,  Christian SCHAEFER ,  Rudolf HOLER

IPC: A23P10/25 ,  B29C48/00 ,  B29C48/04 ,  B29C48/88 ,  B29K105/00

Abstract: The invention relates to an extrusion apparatus for the continuous production of solid food supplements, feed additives or pharmaceutical preparations, which comprise nutritional or pharmaceutical actives homogeneously dispersed in a carrier material matrix. The invention also relates to a method for the production of such preparations by extrusion.

公开(公告)号：US20210000157A1

公开(公告)日：2021-01-07

申请号：US16977302

申请日：2019-03-14

Applicant: DSM IP ASSETS B.V.

Inventor： Jihane ACHKAR ,  Andrea BULBARELLO ,  Alan CONNOLLY ,  Stefanie KIRCHEN ,  Henry RIEGER ,  Simon SPREITER ,  Kai URBAN

IPC: A23P30/20 ,  A23L29/219 ,  A23L29/30 ,  A23L33/155 ,  A23P10/25

Abstract: The present invention relates to extrudates comprising a matrix and vitamin A palmitate. The matrix comprises or consists of octenyl succinate starch and dextrin. Such water-soluble or water-dispersible extrudates have an excellent storage stability and may comprise further components such as other fat-soluble vitamins.

公开(公告)号：US20190380971A1

公开(公告)日：2019-12-19

申请号：US16486572

申请日：2018-02-16

Applicant: DSM IP ASSETS B.V.

Inventor： Jihane ACHKAR ,  Elger FUNDA ,  Loni SCHWEIKERT ,  Kai URBAN ,  Olivia Brigitte VIDONI ,  Ernst ZEDI

IPC: A61K9/50 ,  A61K31/216

Abstract: The present patent application relates to coated particles. These coated particles show improved properties when used in compressed tablets.

公开(公告)号：US20160324877A1

公开(公告)日：2016-11-10

申请号：US15214666

申请日：2016-07-20

Applicant: DSM IP ASSETS B.V.

Inventor： Neil Robert BUCK ,  Wouter CLAERHOUT ,  Bruno H. LEUENBERGER ,  Elisabeth STOECKLIN ,  Kai URBAN ,  Swen WOLFRAM

IPC: A61K31/593 ,  A23L33/155 ,  A61K9/16

CPC classification number: A61K31/593 ,  A23L33/155 ,  A23V2002/00 ,  A61K9/16 ,  A61K31/592 ,  A61K45/06 ,  Y10T428/13 ,  A61K2300/00

Abstract: We disclose compositions comprising Vitamin D (cholecalciferol and /or ergocalciferol) and 25-OH D3 (calcifediol), and use of those compositions to affect at least concentration, bioavailability, metabolism, or efficacy of vitamin D in a human. Forms and dosages of the composition, as well as processes for manufacturing a spray-dried formulation, are also disclosed.

Abstract translation: 我们公开了包含维生素D（胆钙化甾醇和/或麦角钙化醇）和25-OH D3（calcifediol）的组合物，以及使用这些组合物至少影响维生素D在人体中的至少浓度，生物利用度，代谢或功效。 还公开了组合物的形式和剂量，以及用于制造喷雾干燥制剂的方法。

公开(公告)号：US20220071237A1

公开(公告)日：2022-03-10

申请号：US17529121

申请日：2021-11-17

Applicant: DSM IP Assets B.V.

Inventor： Markus BECK ,  Antonio ESTRELLA ,  Elger FUNDA ,  Andrea HITZFELD ,  Christian SCHAEFER ,  Bernd SCHLEGEL ,  Kai URBAN

IPC: A23L2/58 ,  A23L2/395 ,  A23L29/212 ,  A23L5/44 ,  A23L2/52 ,  A23P10/30

Abstract: Beverages are provided which include a beverage liquid and granules mixed with the beverage liquid The granules include: (i) a milled carotenoid consisting of lutein and/or zeaxanthin, wherein the milled carotenoid has the following particle size distribution: D [3,2] in the range of from 0.6 to 1.5 μm, and D [v, 0.5] in the range of from 1.1 to 3.5 μm, (ii) a matrix material which encapsulates the milled carotenoid and comprises at least one modified food starch, a glucose syrup and sucrose, and (iii) a water-soluble antioxidant, wherein the granules have the following particle size distribution: D [3,2] in the range of from 200 to 300 μm, and D [v, 0.5] in the range of from 220 to 320 μm, and wherein all D values are as measured by laser diffraction according to the Fraunhofer scattering model, and wherein the granules do not include an oil or a gelatin.

公开(公告)号：US20210291126A1

公开(公告)日：2021-09-23

申请号：US17257701

申请日：2019-07-12

Applicant: DSM IP ASSETS B.V.

Inventor： Peter RIEBEL ,  Kai URBAN

IPC: B01F3/12 ,  B01F7/00 ,  B01F7/02 ,  B01F7/04

Abstract: The invention relates to an apparatus for the continuous production of a particulate adsorption product, the apparatus comprising: a mixing drum having an elongated cavity for receiving a particulate adsorbent material, an adsorbent inlet and a product outlet, wherein the mixing drum is arranged such that the cavity is inclined in flow direction of the particulate material, and wherein the cavity comprises an initial transport zone adjacent to the inlet and a mixing zone following the initial transport zone; a rotating member extending through the cavity in a longitudinal direction, wherein the rotating member comprises a helical conveying blade at longitudinal positions corresponding to the initial transport zone and mixing instruments at longitudinal positions corresponding to the mixing zone; and one or more injection nozzles for injecting a liquid adsorbate to the mixing zone. The invention further relates to a process for the continuous production of a particulate adsorption product using such apparatus.

公开(公告)号：US20210120844A1

公开(公告)日：2021-04-29

申请号：US17257763

申请日：2019-07-12

Applicant: DSM IP ASSETS B.V.

Inventor： Peter RIEBEL ,  Kai URBAN

IPC: A23K20/105 ,  A23K20/28 ,  A23K50/10 ,  C07C203/04

Abstract: The invention relates to a process for the continuous production of an adsorption product of a nitrooxy-functional organic compound adsorbed on the surface of a particulate adsorbent material, the process comprising the steps of: continuously feeding particulate adsorbent material into an elongated cavity; continuously conveying the material within the cavity in a downstream direction; continuously spraying a liquid adsorbate onto the particulate adsorbent material, wherein the liquid adsorbate comprises the nitrooxy-functional organic compound; continuously agitating the mixture thus obtained to form the adsorption product; and continuously removing the adsorption product from the cavity. The invention further relates to an adsorption product obtained by such process and the use of such adsorption product in ruminant nutrition.