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公开(公告)号：US20220117247A1
公开(公告)日：2022-04-21
申请号：US17429555
申请日：2020-02-13
发明人： Christophe FREMAUX , Philippe HORVATH , Armelle COCHU-BLACHÈRE , Dennis ROMERO , Sylvain MOINEAU , Simon LABRIE
摘要： The present invention relates to a lactic acid bacterium, in particular a strain of the Streptococcus genus, with reduced sensitivity to cos-type bacteriophages. The invention also relates to methods to engineer these lactic acid bacteria as well as their use to ferment milk.
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公开(公告)号：US20240043790A1
公开(公告)日：2024-02-08
申请号：US18050511
申请日：2021-04-29
发明人： Anais JEDRZEJOWSKI , Christophe FREMAUX , Elodie GUILLOU , Sabine VAN DILLEN , Philippe HORVATH , Mikael PIANFETTI
IPC分类号： C12N1/20 , C12N15/74 , A23C19/032 , A23C19/068
CPC分类号： C12N1/205 , C12N1/20 , C12N15/746 , A23C19/0323 , A23C19/0684 , C12R2001/46
摘要： The invention relates to a method for generating a Streptococcus thermophilus strain exhibiting a “high galactose utilization” profile, which is characterized by a high percentage of consumed galactose at the maximum speed of lactose consumption and optionally a high percentage of consumed galactose at the end of lactose consumption (both as determined by assay I), comprising modifying the sequence of the gal-lac gene cluster. The invention also relates to a Streptococcus thermophilus strain obtained or obtainable by this method, to a Streptococcus thermophilus strain characterized both by the sequence of its gal-lac gene cluster and its “high galactose utilization” profile, to a culture and kit-of part comprising such strains, as well as to the use of such strains in food applications.
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