公开(公告)号：US20040265934A1

公开(公告)日：2004-12-30

申请号：US10786076

申请日：2004-02-26

申请人： Dako A/S

发明人： Henrik Stender ,  Kaare Lund ,  Tina Anderson Mollerup

IPC分类号： C12Q001/68 ,  G01N033/554 ,  G01N033/569

CPC分类号： C07K14/003 ,  C12Q1/689

摘要： Novel hybridisation assay probes and mixtures of such probes for detecting a target sequence of one or mycobacteria optionally present in a sample. The probes may suitable be directed to target sequences of mycobacterial rDNA, precursor rRNA, or rRNA, said probes being capable of forming detectable hybrids. The probes are in particular directed to mycobacterial rDNA, to precursor rRNA, or to 23S, 16S or 5S rRNA The probes are useful for detecting the organisms in test samples such as sputum, laryngeal swabs, gastric lavage, bronchial washings, biopsies, aspirates, expectorates, body fluids (spinal, pleural, pericardial, synovial, blood, pus, bone marrow), urine, tissue sections as well as food samples, soil, air and water samples, and cultures thereof.

摘要翻译： 新型杂交测定探针和这种探针的混合物，用于检测任选存在于样品中的一种或分枝杆菌的靶序列。 探针可以适用于分枝杆菌rDNA，前体rRNA或rRNA的靶序列，所述探针能够形成可检测的杂交体。 探针特别针对分枝杆菌rDNA，前体rRNA或23S，16S或5S rRNA。探针可用于检测测试样品中的生物体，如痰液，喉拭子，胃灌洗液，支气管洗涤液，活检组织，抽吸液， 痰液，体液（脊髓，胸膜，心包，滑液，血液，脓液，骨髓），尿液，组织切片以及食物样品，土壤，空气和水样品及其培养物。

公开(公告)号：US20040063110A1

公开(公告)日：2004-04-01

申请号：US10347510

申请日：2003-01-21

申请人： Dako A/S

发明人： Henrik Stender ,  Kaare Lund ,  Tina Anderson Mollerup

IPC分类号： C12Q001/68 ,  C07K014/00

CPC分类号： C07K14/003 ,  C12Q1/689

摘要： Novel hybridisation assay probes and mixtures of such probes for detecting a target sequence of one or mycobacteria optionally present in a sample. The probes may suitable be directed to target sequences of mycobacterial rDNA, precursor rRNA, or rRNA, said probes being capable of forming detectable hybrids. The probes are in particular directed to mycobacterial rDNA, to precursor rRNA, or to 23S, 16S or 5S rRNA. The probes are useful for detecting the organisms in test samples such as sputum, laryngeal swabs, gastric lavage, bronchial washings, biopsies, aspirates, expectorates, body fluids (spinal, pleural, pericardial, synovial, blood, pus, bone marrow), urine, tissue sections as well as food samples, soil, air and water samples, and cultures thereof.

摘要翻译： 新型杂交测定探针和这种探针的混合物，用于检测任选存在于样品中的一种或分枝杆菌的靶序列。 探针可以适用于分枝杆菌rDNA，前体rRNA或rRNA的靶序列，所述探针能够形成可检测的杂交体。 探针特别针对分枝杆菌rDNA，前体rRNA或23S，16S或5S rRNA。 探针可用于检测试验样品中的生物体，如痰液，喉拭子，胃灌洗液，支气管洗液，活组织检查，抽吸物，痰液，体液（脊髓，胸膜，心包，滑液，血液，脓液，骨髓），尿液 ，组织切片以及食物样品，土壤，空气和水样品及其培养物。