Methods for characterizing glycoproteins and generating antibodies for same
    3.
    发明授权
    Methods for characterizing glycoproteins and generating antibodies for same 有权
    表征糖蛋白并产生相同抗体的方法

    公开(公告)号:US08222208B2

    公开(公告)日:2012-07-17

    申请号:US13007393

    申请日:2011-01-14

    IPC分类号: A61K38/00 C07K14/00

    CPC分类号: C07K16/28

    摘要: The invention provides methods for preparing a peptide as an immunogen to generate an antibody specific for the deglycosylated form of a glycopolypeptide by preparing a peptide that includes an N-linked glycosylation site of said glycopolypeptide and identifying a peptide sequence that includes said glycosylated site and preparing said peptide wherein N of said site is converted to D.

    摘要翻译: 本发明提供了制备肽作为免疫原的方法,通过制备包含所述糖多肽的N-连接的糖基化位点的肽并鉴定包含所述糖基化位点的肽序列并制备了包含所述糖基化位点的肽序列,从而产生对糖多糖的去糖基化形式特异性的抗体 所述肽,其中所述位点的N转化为D.

    Methods for characterizing glycoproteins and generating antibodies for same
    4.
    发明授权
    Methods for characterizing glycoproteins and generating antibodies for same 有权
    表征糖蛋白并产生相同抗体的方法

    公开(公告)号:US07879799B2

    公开(公告)日:2011-02-01

    申请号:US11891487

    申请日:2007-08-09

    IPC分类号: A61K38/00 C07K14/00

    CPC分类号: C07K16/28

    摘要: The invention provides methods for generating an antibody specific for the deglycosylated form of a glycopolypeptide using a peptide corresponding to an N-linked glycosylation site of a glycopolypeptide. The invention additionally provides methods for generating an antibody specific for a glycopolypeptide using a peptide corresponding to amino acids adjacent to an authentic N-linked glycosylation site.

    摘要翻译: 本发明提供使用对应于糖多肽的N-连接糖基化位点的肽产生对糖多糖形式的去糖基化形式特异的抗体的方法。 本发明另外提供了使用对应于与真实N-连接的糖基化位点相邻的氨基酸的肽来产生对糖多肽特异性的抗体的方法。

    Methods for characterizing glycoproteins and generating antibodies for same
    6.
    发明申请
    Methods for characterizing glycoproteins and generating antibodies for same 有权
    表征糖蛋白并产生相同抗体的方法

    公开(公告)号:US20080108152A1

    公开(公告)日:2008-05-08

    申请号:US11891487

    申请日:2007-08-09

    IPC分类号: C07K16/18

    CPC分类号: C07K16/28

    摘要: The invention provides methods for generating an antibody specific for the deglycosylated form of a glycopolypeptide using a peptide corresponding to an N-linked glycosylation site of a glycopolypeptide. The invention additionally provides methods for generating an antibody specific for a glycopolypeptide using a peptide corresponding to amino acids adjacent to an authentic N-linked glycosylation site.

    摘要翻译: 本发明提供使用对应于糖多肽的N-连接糖基化位点的肽产生对糖多糖形式的去糖基化形式特异的抗体的方法。 本发明另外提供了使用对应于与真实N-连接的糖基化位点相邻的氨基酸的肽来产生对糖多肽特异性的抗体的方法。

    Accuracy of the estimation of computer resource usage
    8.
    发明申请
    Accuracy of the estimation of computer resource usage 审中-公开
    计算机资源使用估计的准确性

    公开(公告)号:US20060179136A1

    公开(公告)日:2006-08-10

    申请号:US10540909

    申请日:2002-12-27

    IPC分类号: G06F15/173

    摘要: The present invention provides a method and system (1) for improving the accuracy of an estimate of computing system resource usage, the method comprising the steps of obtaining utilization data of system resource and first transaction count data, obtaining further transaction count data and processing the transaction count data and further transaction data to provide an improved estimate of the number of transactions executed during a given time interval.

    摘要翻译: 本发明提供一种用于提高计算系统资源使用估计精度的方法和系统(1),该方法包括以下步骤:获取系统资源和第一事务计数数据的利用数据,获得进一步的事务计数数据并处理 交易计数数据和另外的交易数据,以提供在给定时间间隔内执行的交易数量的改进估计。

    Component design by tables within tables
    9.
    发明申请
    Component design by tables within tables 审中-公开
    组件按表格的形式设计

    公开(公告)号:US20060230046A1

    公开(公告)日:2006-10-12

    申请号:US11094609

    申请日:2005-03-30

    IPC分类号: G06F7/00

    摘要: An apparatus for and method of utilizing an Internet terminal coupled to the world wide web to interface with an existing proprietary data base management system by building a component which accesses said proprietary data base management system. A central process provides a listing of tables or steps to a use at the Internet terminal. The user selects an ordered subset of the list which defines the desired component. The component design is stored as this ordered subset. The design may be subsequently converted to script, as convenient, for run-time execution.

    摘要翻译: 一种利用连接到万维网的因特网终端的装置和方法,通过构建访问所述专有数据库管理系统的组件,与现有的专有数据库管理系统进行接口。 中央流程提供了在互联网终端上使用的表或步骤的列表。 用户选择定义所需组件的列表的有序子集。 组件设计存储为此有序子集。 随后可以将设计转换为脚本,方便运行时执行。