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1.发明申请COMPOSITIONS, METHODS AND USES FOR EXPRESSION OF ENTEROBACTERIUM-ASSOCIATED PEPTIDES 审中-公开组合物，用于表达肠壁菌相关肽的方法和用途公开(公告)号：US20150343046A1
公开(公告)日：2015-12-03
申请号：US14679944
申请日：2015-04-06
CPC分类号： A61K39/025 , A61K39/0291 , A61K2039/5256 , A61K2039/53 , C07K14/24 , C12N7/00 , C12N15/86 , C12N2710/24134 , C12N2710/24141 , C12N2710/24143 , C12N2710/24171 , C12N2840/002 , C12N2840/85 , Y02A50/407
摘要： Embodiments of the present invention generally disclose methods, compositions and uses for generating and expressing enterobacterial-associated peptides. In some embodiments, enterobacterial-associated peptides include, but are not limited to plague-associated peptides. In certain embodiments, methods generally relate to making and using compositions of constructs including, but not limited to, attenuated or modified vaccinia virus vectors expressing enterobacterial-associated peptides. In other embodiments, vaccine compositions are reported of use in a subject.
摘要翻译： 本发明的实施方案通常公开了用于产生和表达肠细菌相关肽的方法，组合物和用途。 在一些实施方案中，肠细菌相关肽包括但不限于瘟疫相关肽。 在某些实施方案中，方法通常涉及制备和使用构建体的组合物，包括但不限于表达肠细菌相关肽的减毒或修饰的痘苗病毒载体。 在其它实施方案中，报告了在受试者中使用的疫苗组合物。
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公开(公告)号：US20130149338A1
公开(公告)日：2013-06-13
申请号：US13492884
申请日：2012-06-10
CPC分类号： A61K39/12 , A61K45/06 , A61K2039/5254 , A61K2039/54 , A61K2039/545 , A61K2039/70 , C12N2770/24134 , Y02A50/386
摘要： Embodiments of the present invention report compositions and methods for vaccinating a subject against all dengue virus serotypes. In some embodiments, multiple vaccine compositions may be administered to a subject in different anatomical locations in order to induce a rapid response to all dengue virus serotypes. In certain embodiments, administration of two or more vaccine compositions to a subject against all dengue virus serotypes may include two or more routes of administration.
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3.发明申请公开(公告)号：US20100303860A1
公开(公告)日：2010-12-02
申请号：US12790511
申请日：2010-05-28
CPC分类号： A61K39/12 , A61K9/0019 , A61K2039/5254 , A61K2039/54 , A61K2039/545 , A61K2039/70 , C12N2770/24134 , Y02A50/386 , Y02A50/407
摘要： Embodiments of the present invention report compositions and methods for vaccinating a subject against dengue viruses. In some embodiments, vaccine compositions may be administered by intradermal introduction. In certain embodiments, intradermal introduction in a subject of a vaccine against dengue virus may include one or more intradermal boosts after initial vaccination. Other embodiments include intradermal injection of a vaccine composition against dengue virus wherein the composition provides protection against two or more of DEN-1, DEN-2, DEN-3 and DEN-4.
摘要翻译： 本发明的实施方案报道了针对登革热病毒接种受试者的组合物和方法。 在一些实施方案中，疫苗组合物可以通过皮内引入来施用。 在某些实施方案中，针对登革热病毒的疫苗的受试者中皮内引入可以在初次接种后包括一种或多种皮内加压。 其他实施方案包括疫苗组合物针对登革热病毒的皮内注射，其中所述组合物提供对DEN-1，DEN-2，DEN-3和DEN-4中的两种或更多种的保护。
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