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公开(公告)号：US20100016740A1
公开(公告)日：2010-01-21
申请号：US12173780
申请日：2008-07-15
CPC分类号： A61N1/365 , A61B5/0031 , A61N1/368 , A61N1/3702 , A61N1/37258 , A61N1/37282 , A61N1/37288
摘要： A cardiac ischemic protection system and method for conditioning a patient's heart is provided. The method can include detecting acute myocardial infarction, angina pectoris, silent ischemia, or stunning and providing closed-loop dyssynchronous pacing to the patient's heart to precondition and/or postcondition the patient's heart in order to reduce ischemic damage.
摘要翻译： 提供了用于调节患者心脏的心脏缺血保护系统和方法。 该方法可以包括检测急性心肌梗塞，心绞痛，静息缺血或惊恐，并向患者的心脏提供闭环异步起搏以预先和/或后置病人的心脏以减少缺血性损伤。
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公开(公告)号：US20100292768A1
公开(公告)日：2010-11-18
申请号：US12782465
申请日：2010-05-18
IPC分类号： A61N1/05
CPC分类号： A61N1/0573
摘要： Electrical medical leads having active fixation electrodes, particularly helix electrodes intended to be screwed into body tissue, e.g., the heart, are disclosed having selectively applied insulation to optimize exposed electrode surface area and dispose the exposed electrode surface area toward tissue that is less traumatized by injury caused by screwing in the fixation helix. In a preferred fabrication method, an outer helical surface is masked by contact with a masking tube while a dielectric coating is applied to the inner helical surface of the coil turns of the helix, and the masking tube is removed when the dielectric coating has set. In one variation, at least one aperture is formed through the masking tube sidewall exposing an area of the outer helical surface thereby interrupting the uninsulated outer helical electrode.
摘要翻译： 公开了具有主动固定电极的电医疗引线，特别是旨在拧入身体组织（例如心脏）的螺旋电极，其具有选择性地施加的绝缘体以优化暴露的电极表面积，并将暴露的电极表面区域设置成较少受到创伤的组织 螺钉固定螺旋引起的损伤。 在优选的制造方法中，外部螺旋表面通过与掩蔽管的接触而被掩蔽，同时将电介质涂层施加到螺旋线圈匝的内螺旋形表面，并且当电介质涂层固化时，掩蔽管被去除。 在一个变型中，通过掩蔽管侧壁形成至少一个孔，暴露外螺旋表面的一个区域，从而中断未绝缘的外螺旋电极。
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3.发明申请公开(公告)号：US20100137963A1
公开(公告)日：2010-06-03
申请号：US12640610
申请日：2009-12-17
CPC分类号： A61N1/05 , C23C28/32 , Y10T29/49204
摘要： A method for fabricating an implantable medical electrode includes roughening the electrode substrate, applying an adhesion layer, and depositing a valve metal oxide coating over the adhesion layer under conditions optimized to minimize electrode impedance and post-pulse polarization. The electrode substrate may be a variety of electrode metals or alloys including titanium, platinum, platinum-iridium, or niobium. The adhesion layer may be formed of titanium or zirconium. The valve metal oxide coating is a ruthenium oxide coating sputtered onto the adhesion layer under controlled target power, sputtering pressure, and sputter gas ratio setting optimized to minimize electrode impedance and post-pulse polarization.
摘要翻译： 一种用于制造可植入医疗电极的方法包括使电极基板粗糙化，施加粘合层，以及在优化以最小化电极阻抗和脉冲后极化的条件下，在粘附层上沉积阀金属氧化物涂层。 电极基板可以是各种电极金属或包括钛，铂，铂 - 铱或铌的合金。 粘合层可以由钛或锆形成。 阀金属氧化物涂层是在受控目标功率，溅射压力和溅射气体比设置下溅射到粘附层上的氧化钌涂层，其被优化以最小化电极阻抗和后脉冲极化。
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