专利检索 ap:("Daniel Cua" OR "Holly Cherwinski" OR "Adele Wang" OR "Yi Chen" OR "Barbara Joyce-Shaikh" OR "Merck Sharp & Dohme Corp.") AND inv:"Adele Wang" 第 1 页

1.

发明授权
ILT3 ligand 有权

公开(公告)号：US11370839B2

公开(公告)日：2022-06-28

申请号：US16342582

申请日：2017-11-10

申请人： Daniel Cua , Holly Cherwinski , Adele Wang , Yi Chen , Barbara Joyce-Shaikh , Merck Sharp & Dohme Corp.

发明人： Daniel Cua , Holly Cherwinski , Adele Wang , Yi Chen , Barbara Joyce-Shaikh

IPC分类号： C07K16/28 , A61P35/00 , G01N33/542 , A61K39/00

摘要： The present invention provides antibodies and antigen-binding fragments thereof that bind ILT3, ILT3 ligand (i.e., PI16) or a complex between ILT3 and the ILT3 ligand. Methods for determining whether ILT3 and the ILT3 ligand bind together or whether a substance agonizes or antagonizes such binding are also provided.

2.

发明申请
ILT3 LIGAND 审中-公开

公开(公告)号：US20190241655A1

公开(公告)日：2019-08-08

申请号：US16342582

申请日：2017-11-06

申请人： Daniel CUA , Holly CHERWINSKI , Adele WANG , Yi CHEN , Barbara JOYCE-SHAIKH , Merck Sharp & Dohme Corp.

发明人： Daniel Cua , Holly Cherwinski , Adele Wang , Yi Chen , Barbara Joyce-Shaikh

IPC分类号： C07K16/28 , G01N33/542 , A61P35/00

CPC分类号： C07K16/2803 , A61K2039/505 , A61P35/00 , C07K2317/32 , C07K2317/76 , G01N33/542

摘要： The present invention provides antibodies and antigen-binding fragments thereof that bind ILT3, ILT3 ligand (i.e., PI16) or a complex between ILT3 and the ILT3 ligand. Methods for determining whether ILT3 and the ILT3 ligand bind together or whether a substance agonizes or antagonizes such binding are also provided.