专利检索 ap:("Daniel Patrick Walker" OR "Eric Jon Jacobsen" OR "David W. Piotrowski" OR "Brad A. Acker" OR "Donn G. Wishka" OR "Jeffrey W. Corbett" OR "Mark R. Rauckhorst" OR "Vincent E. Groppi, Jr.") AND inv:"Mark R. Rauckhorst" 第 1 页

1.

发明授权
N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease 失效
标题翻译：用于治疗疾病的N-（氮杂双环部分） - 取代的杂双环芳族化合物

公开(公告)号：US06849620B2

公开(公告)日：2005-02-01

申请号：US10272802

申请日：2002-10-17

申请人： Daniel Patrick Walker , Eric Jon Jacobsen , David W. Piotrowski , Brad A. Acker , Donn G. Wishka , Jeffrey W. Corbett , Mark R. Rauckhorst , Vincent E. Groppi, Jr.

发明人： Daniel Patrick Walker , Eric Jon Jacobsen , David W. Piotrowski , Brad A. Acker , Donn G. Wishka , Jeffrey W. Corbett , Mark R. Rauckhorst , Vincent E. Groppi, Jr.

IPC分类号： A61K31/435 , A61K31/44 , C07D453/00 , C07D471/02 , C07D471/08 , C07D487/08 , C07D491/02 , C07D498/02

CPC分类号： C07D487/08 , C07D453/02 , C07D471/08

摘要： The invention provides compounds of Formula I: wherein Azabicyclo is W0 is a bicyclic moiety and is These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals in which α7 is known to be involved.

摘要翻译： 本发明提供了式I化合物：其中氮杂双环是W 2是双环部分，并且这些化合物可以是药物盐或组合物的形式，可以是纯对映体形式或外消旋混合物，并且可用于其中α7 已知涉及。