公开(公告)号：US20140227754A1

公开(公告)日：2014-08-14

申请号：US14172790

申请日：2014-02-04

Applicant: Danisco US Inc.

Inventor： Wolfgang Aehle ,  Richard R. Bott ,  Martijn Scheffers ,  Pieter van Solingen ,  Casper Vroemen

IPC: C12N9/34 ,  C12P7/06

CPC classification number: C12N9/2428 ,  C12P7/06 ,  C12P19/02 ,  C12P19/14 ,  Y02E50/17

Abstract: The present disclosure relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present disclosure provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions and cleaning compositions. The disclosure also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.

Abstract translation: 本公开涉及具有改变的性质（例如改善的热稳定性和/或比活性）的母体葡糖淀粉酶的变体。 特别地，本公开提供了包含变体葡糖淀粉酶的组合物，包括淀粉水解组合物和清洁组合物。 本公开还涉及编码在宿主细胞中产生葡糖淀粉酶变体的变体和方法的DNA构建体。

公开(公告)号：US09290753B2

公开(公告)日：2016-03-22

申请号：US14172790

申请日：2014-02-04

Applicant: Danisco US Inc.

Inventor： Wolfgang Aehle ,  Richard R. Bott ,  Martijn Scheffers ,  Pieter van Solingen ,  Casper Vroemen

IPC: C12N15/56 ,  C12N9/34 ,  C12P7/06 ,  C12P19/14 ,  C12P19/02

CPC classification number: C12N9/2428 ,  C12P7/06 ,  C12P19/02 ,  C12P19/14 ,  Y02E50/17

Abstract: The present disclosure relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present disclosure provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions and cleaning compositions. The disclosure also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.