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    Injectable Microspheres
    4.
    发明申请
    Injectable Microspheres 有权
    可注射微球

    公开(公告)号：US20110151004A1

    公开(公告)日：2011-06-23

    申请号：US13015193

    申请日：2011-01-27

    申请人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    发明人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    IPC分类号： A61K9/14 ,  B32B5/16 ,  C08G63/08

    CPC分类号： A61K9/0019 ,  A61K9/1647 ,  Y10T428/2982

    摘要： Injectable microspheres are obtained from double bond functionalized polyhydric alcohol ester by a method comprising dissolving the double bond functionalized esters in a hydrophobic organic solvent, forming an aqueous solution of stabilizer, forming an oil in water emulsion where the solution of stabilizer constitutes the continuous phase and the solution of ester constitutes the disperse phase and evaporating the organic solvent or from block copolymer of PGCLM and methoxy poly(ethylene glycol).

    摘要翻译： 可注射的微球体是通过将双键官能化的酯溶解在疏水性有机溶剂中，形成稳定剂的水溶液，形成稳定剂溶液形成连续相的水乳液的方法从双键官能化的多元醇酯得到的， 酯溶液构成分散相并蒸发有机溶剂或由PGCLM和甲氧基聚（乙二醇）的嵌段共聚物蒸发。

    Hydrogel forming system comprising PEG derivative precursor
    5.
    发明授权
    Hydrogel forming system comprising PEG derivative precursor 有权
    包含PEG衍生物前体的水凝胶形成体系

    公开(公告)号：US07670616B2

    公开(公告)日：2010-03-02

    申请号：US11060279

    申请日：2005-02-18

    申请人： Daqing Wu ,  Chih-Chang Chu

    发明人： Daqing Wu ,  Chih-Chang Chu

    IPC分类号： A61F2/02

    CPC分类号： A61L31/10 ,  A61L31/145 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/00

    摘要： Variation in precursor ratio and mass of double bond functionalized polyhydric alcohol precursor and polyethylene glycol diacrylate precursor provide a wide range of release rates of drug or other biologically active agent from hydrogel formed therefrom.

    摘要翻译： 双键官能化多元醇前体和聚乙二醇二丙烯酸酯前体的前体比和质量的变化提供药物或其它生物活性剂从其形成的水凝胶的宽范围的释放速率。

    Injectable microspheres
    6.
    发明授权
    Injectable microspheres 有权
    可注射微球

    公开(公告)号：US08092835B1

    公开(公告)日：2012-01-10

    申请号：US13269738

    申请日：2011-10-10

    申请人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    发明人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    IPC分类号： A61K9/14

    CPC分类号： A61K9/0019 ,  A61K9/1647 ,  Y10T428/2982

    摘要： Injectable microspheres are obtained from double bond functionalized polyhydric alcohol ester by a method comprising dissolving the double bond functionalized esters in a hydrophobic organic solvent, forming an aqueous solution of stabilizer, forming an oil in water emulsion where the solution of stabilizer constitutes the continuous phase and the solution of ester constitutes the disperse phase and evaporating the organic solvent or from block copolymer of PGCLM and methoxy poly(ethylene glycol).

    摘要翻译： 可注射的微球体是通过将双键官能化的酯溶解在疏水性有机溶剂中，形成稳定剂的水溶液，形成稳定剂溶液形成连续相的水乳液的方法从双键官能化的多元醇酯得到的， 酯溶液构成分散相并蒸发有机溶剂或由PGCLM和甲氧基聚（乙二醇）的嵌段共聚物蒸发。

    Hydrogel forming system comprising peg derivative precursor
    7.
    发明申请
    Hydrogel forming system comprising peg derivative precursor 有权
    包含栓衍生物前体的水凝胶形成体系

    公开(公告)号：US20050202060A1

    公开(公告)日：2005-09-15

    申请号：US11060279

    申请日：2005-02-18

    申请人： Daqing Wu ,  Chih-Chang Chu

    发明人： Daqing Wu ,  Chih-Chang Chu

    IPC分类号： A61F2/00

    CPC分类号： A61L31/10 ,  A61L31/145 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/00

    摘要： Variation in precursor ratio and mass of double bond functionalized polyhydric alcohol precursor and polyethylene glycol diacrylate precursor provide a wide range of release rates of drug or other biologically active agent from hydrogel formed therefrom.

    摘要翻译： 双键官能化多元醇前体和聚乙二醇二丙烯酸酯前体的前体比和质量的变化提供药物或其它生物活性剂从其形成的水凝胶的宽范围的释放速率。

    Injectable microspheres
    8.
    发明授权
    Injectable microspheres 有权
    可注射微球

    公开(公告)号：US08034383B2

    公开(公告)日：2011-10-11

    申请号：US13015193

    申请日：2011-01-27

    申请人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    发明人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    IPC分类号： A61K9/14

    CPC分类号： A61K9/0019 ,  A61K9/1647 ,  Y10T428/2982

    摘要： Injectable microspheres are obtained from double bond functionalized polyhydric alcohol ester by a method comprising dissolving the double bond functionalized esters in a hydrophobic organic solvent, forming an aqueous solution of stabilizer, forming an oil in water emulsion where the solution of stabilizer constitutes the continuous phase and the solution of ester constitutes the disperse phase and evaporating the organic solvent or from block copolymer of PGCLM and methoxy poly(ethylene glycol).

    摘要翻译： 可注射的微球体是通过将双键官能化的酯溶解在疏水性有机溶剂中，形成稳定剂的水溶液，形成稳定剂溶液形成连续相的水乳液的方法从双键官能化的多元醇酯得到的， 酯溶液构成分散相并蒸发有机溶剂或由PGCLM和甲氧基聚（乙二醇）的嵌段共聚物蒸发。

    Injectable microspheres
    9.
    发明申请
    Injectable microspheres 审中-公开
    可注射微球

    公开(公告)号：US20060013886A1

    公开(公告)日：2006-01-19

    申请号：US11148662

    申请日：2005-06-09

    申请人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    发明人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    IPC分类号： A61K9/14

    CPC分类号： A61K9/0019 ,  A61K9/1647 ,  Y10T428/2982

    摘要： Injectable microspheres are obtained from double bond functionalized polyhydric alcohol ester by a method comprising dissolving the double bond functionalized esters in a hydrophobic organic solvent, forming an aqueous solution of stabilizer, forming an oil in water emulsion where the solution of stabilizer constitutes the continuous phase and the solution of ester constitutes the disperse phase and evaporating the organic solvent or from block copolymer of PGCLM and methoxy poly(ethylene glycol).

    摘要翻译： 可注射的微球体是通过将双键官能化的酯溶解在疏水性有机溶剂中，形成稳定剂的水溶液，形成稳定剂溶液形成连续相的水乳液的方法从双键官能化的多元醇酯得到的， 酯溶液构成分散相并蒸发有机溶剂或由PGCLM和甲氧基聚（乙二醇）的嵌段共聚物蒸发。