公开(公告)号：US20130078307A1

公开(公告)日：2013-03-28

申请号：US13240500

申请日：2011-09-22

申请人： Darrell Holton, JR. ,  Nelly Fransen ,  Matt Reddick

发明人： Darrell Holton, JR. ,  Nelly Fransen ,  Matt Reddick

IPC分类号： A61K31/465 ,  A61P25/00 ,  A61P25/34 ,  A61K31/787 ,  A61K9/14

CPC分类号： A61K47/26 ,  A23L27/10 ,  A23L27/2028 ,  A23L27/33 ,  A23L27/40 ,  A61K9/0056 ,  A61K9/20 ,  A61K9/7007 ,  A61K31/465

摘要： A composition intended to be employed for therapeutic purposes incorporates a nicotinic compound, a sugar substitute, and a sugar alcohol syrup. Representative forms of nicotine include free base (e.g., as a mixture of nicotine and microcrystalline cellulose), a nicotine salt (e.g., as nicotine bitartrate) or nicotine polacrilex. The composition is useful for treatment of central nervous system conditions, diseases, and disorders, and as a nicotine replacement therapy.

公开(公告)号：US20130098377A1

公开(公告)日：2013-04-25

申请号：US13278877

申请日：2011-10-21

申请人： August Joseph Borschke ,  Darrell Holton, JR.

发明人： August Joseph Borschke ,  Darrell Holton, JR.

IPC分类号： A61K31/465 ,  A24F23/02 ,  A61P25/00 ,  A61K31/785 ,  A61P25/34 ,  A24F47/00 ,  A61K9/14

CPC分类号： A61K9/0056 ,  A61K9/0043 ,  A61K9/0058 ,  A61K31/465

摘要： A composition intended to be employed for therapeutic purposes incorporates an active ingredient (e.g., a source of nicotine) and at a non-active ingredient that is carried by a porous substrate. The non-active ingredient can be a substance that has the capability of affecting the pH of the biological system to which it is applied (e.g., basic substance and/or buffering agent is sorbed onto the porous carrier, so as to be in intimate contact with that carrier). Representative forms of nicotine include free base (e.g., as a mixture of nicotine and microcrystalline cellulose), a nicotine salt (e.g., as nicotine bitartrate) and nicotine polacrilex. The basic substance can be sodium carbonate, and the porous substrate can be microcrystalline cellulose. The composition is useful for treatment of central nervous system conditions, diseases, and disorders, and can be used as a nicotine replacement therapy.

摘要翻译： 旨在用于治疗目的的组合物包含活性成分（例如，尼古丁来源）和由多孔底物携带的非活性成分。 非活性成分可以是具有影响其所施用的生物系统的pH的能力的物质（例如，碱性物质和/或缓冲剂被吸附到多孔载体上，以便紧密接触 与该承运人）。 尼古丁的代表性形式包括游离碱（例如，作为尼古丁和微晶纤维素的混合物），尼古丁盐（例如，作为酒石酸烟碱）和尼古丁polacrilex。 碱性物质可以是碳酸钠，多孔基材可以是微晶纤维素。 该组合物可用于治疗中枢神经系统疾病和疾病，并可用作尼古丁替代疗法。

公开(公告)号：US20130074856A1

公开(公告)日：2013-03-28

申请号：US13614673

申请日：2012-09-13

申请人： Darrell Holton, JR.

发明人： Darrell Holton, JR.

IPC分类号： A24B13/00 ,  A24B15/30

CPC分类号： A24B13/00 ,  A23G3/48 ,  A24B15/24 ,  A24B15/245 ,  A24B15/30

摘要： A smokeless tobacco product is provided that includes a tobacco material in the form of a tobacco extract, a particulate tobacco material, or a combination thereof. In some embodiments, the smokeless tobacco product is substantially translucent. Methods for making and using the smokeless tobacco product are also provided. The smokeless tobacco product can include isomalt, maltitol syrup, particulate tobacco, and a translucent tobacco extract prepared by ultrafiltration.

公开(公告)号：US20130074855A1

公开(公告)日：2013-03-28

申请号：US13240525

申请日：2011-09-22

申请人： Darrell Holton, JR.

发明人： Darrell Holton, JR.

IPC分类号： A24B15/30 ,  B01D35/18 ,  A24B15/00

CPC分类号： A24B15/24 ,  A24B15/10 ,  A24B15/30

摘要： The invention provides a smokeless tobacco product comprising a tobacco extract. In some embodiments, the smokeless tobacco product is translucent. The invention further provides methods for making and using the smokeless tobacco product. In certain embodiments, the smokeless tobacco product comprises isomalt, maltitol syrup, and a translucent tobacco extract prepared by ultrafiltration.