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公开(公告)号:US5635189A
公开(公告)日:1997-06-03
申请号:US297215
申请日:1994-08-29
Applicant: David F. Horrobin , Mehar S. Manku
Inventor: David F. Horrobin , Mehar S. Manku
IPC: A23L33/15 , A61K8/00 , A61K8/49 , A61K8/67 , A61K31/355 , A61P3/02 , A61Q19/00 , C07D311/72 , A61K9/14
CPC classification number: C07D311/72
Abstract: A natural vitamin E preparation, i.e. vitamin E extracted from natural sources, comprising one or more of the alpha-, beta-, gamma- and delta-tocopherol forms, either as the tocopherol itself, or as a derivative, such as the acetate, in which the total concentration of Wendt PAHs is less than 100 ppb.
Abstract translation: 天然维生素E制剂,即从天然来源提取的维生素E,其包含α,β,γ和δ-生育酚形式中的一种或多种,作为生育酚本身,或作为衍生物,例如乙酸盐, 其中Wendt PAHs的总浓度小于100ppb。
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公开(公告)号:US5466841A
公开(公告)日:1995-11-14
申请号:US187042
申请日:1994-01-27
Applicant: David F. Horrobin , Austin McMordie , Mehar S. Manku
Inventor: David F. Horrobin , Austin McMordie , Mehar S. Manku
IPC: A23J7/00 , A61K8/00 , A61K8/55 , A61K8/58 , A61K8/96 , A61K38/00 , A61Q19/00 , C07F9/10 , C07F9/113 , C07F9/117 , C07F9/02
Abstract: A phospholipid comprising two different unsaturated fatty acids, the fatty acids being selected from the twelve n-6 and n-3 essential fatty acids, oleic acid, parinaric acid and combinic acid.
Abstract translation: 包含两种不同不饱和脂肪酸的磷脂,所述脂肪酸选自十二个n-6和n-3必需脂肪酸,油酸,对苯二酸和组合酸。
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公开(公告)号:US4965075A
公开(公告)日:1990-10-23
申请号:US273680
申请日:1988-11-21
Applicant: David F. Horrobin , Stephen C. Cunnane , Mehar S. Manku
Inventor: David F. Horrobin , Stephen C. Cunnane , Mehar S. Manku
IPC: A61K31/20 , A61K31/201 , A61K31/202 , A61K31/30 , A61K33/34 , A61P3/06 , A61P7/02 , A61P9/00 , A61P11/00 , A61P13/02 , A61P15/00 , A61P25/18 , A61P29/00 , A61P35/00 , A61P43/00
CPC classification number: A61K31/20 , A61K33/34 , Y10S514/866
Abstract: Methods of influencing the 1-series/2-series PG balance in the body by administering a composition containing .gamma.-linolenic acid and/or dihomo-.gamma.-linolenic acid and assimilable copper compounds optionally with a diluent or carrier, the acids being as such or as derivatives convertible in the body thereto. The amounts of the acids or derivatives are 0.2 to 10 g (calculated as .gamma.-linolenic acid) and of copper compounds are 0.1 to 100 mg (calculated as copper).
Abstract translation: 通过施用含有γ-亚麻酸和/或二 - γ-亚麻酸的组合物和任选地与稀释剂或载体同化的铜化合物来影响体内1系/ 2系PG平衡的方法,酸如此 或作为在体内可转换的衍生物。 酸或衍生物的量为0.2〜10g(以γ-亚麻酸计算),铜化合物的量为0.1〜100mg(以铜计)。
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公开(公告)号:US4666701A
公开(公告)日:1987-05-19
申请号:US839228
申请日:1986-03-13
Applicant: David F. Horrobin , Mehar S. Manku , Yung S. Huang
Inventor: David F. Horrobin , Mehar S. Manku , Yung S. Huang
CPC classification number: A61K31/20 , A61K31/23 , Y10S514/922
Abstract: Gamma-linolenic acid or dihomo-gamma-linolenic acid for use in the reduction or prevention of gastro-intestinal bleeding and other side effects shown by NSAIDs when administered on a continuing basis, including use in allowing said administration to be replaced by administration of said acid alone in arthritis and other conditions without exacerbation of symptoms.
Abstract translation: 用于减少或预防胃肠道出血的γ-亚麻酸或二 - 亚麻酸,以及NSAIDs持续施用时所显示的其它副作用,包括用于允许所述给药被施用所述 酸单独在关节炎等条件下无症状加重。
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