专利检索 ap:("David Paul Humphreys" OR "Daniel John Lightwood" OR "Kerry Louise Tyson" OR "David Edward Ormonde Knight" OR "Karine Jeannine Madeleine Hervé" OR "Joanne Elizabeth Compson" OR "Matthew Jon Timothy Page" OR "Andrew Charles Payne" OR "Nicola Louise Fisher" OR "Brendon Mackenze" OR "Matthew Cox") AND inv:"Brendon Mackenze" 第 1 页

1.

发明申请
NEUTRALISING ANTIBODIES TO THE MAJOR EXOTOXINS TCDA AND TCDB OF CLOSTRIDIUM DIFFICILE 审中-公开
标题翻译：中枢性抗体对主要外源性TCDA和TCDB的CLOSTRIDIUM DIFFICILE

公开(公告)号：US20140348844A1

公开(公告)日：2014-11-27

申请号：US14344637

申请日：2012-09-10

申请人： David Paul Humphreys , Daniel John Lightwood , Kerry Louise Tyson , David Edward Ormonde Knight , Karine Jeannine Madeleine Hervé , Joanne Elizabeth Compson , Matthew Jon Timothy Page , Andrew Charles Payne , Nicola Louise Fisher , Brendon Mackenze , Matthew Cox

发明人： David Paul Humphreys , Daniel John Lightwood , Kerry Louise Tyson , David Edward Ormonde Knight , Karine Jeannine Madeleine Hervé , Joanne Elizabeth Compson , Matthew Jon Timothy Page , Andrew Charles Payne , Nicola Louise Fisher , Brendon Mackenze , Matthew Cox

IPC分类号： C07K16/12 , G01N33/573 , G01N33/68 , G01N33/569 , A61K39/40 , A61K45/06

摘要： This present invention describes the derivation and selection of antibodies capable of neutralising the major exotoxins; TcdA and TcdB of Clostridium difficile. The invention also describes novel neutralisation and antigen binding properties of individual Mabs and mixtures thereof.

摘要翻译： 本发明描述了能够中和主要外毒素的抗体的衍生和选择; 艰难梭菌的TcdA和TcdB。本发明还描述了单个Mab及其混合物的新型中和和抗原结合性质。