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公开(公告)号:US5882671A
公开(公告)日:1999-03-16
申请号:US786170
申请日:1997-01-21
申请人: David Reed Helton , Mary Jeanne Kallman , James Allen Monn , Darryle Darwin Schoepp , Joseph Patrick Tizzano
发明人: David Reed Helton , Mary Jeanne Kallman , James Allen Monn , Darryle Darwin Schoepp , Joseph Patrick Tizzano
IPC分类号: A61K45/00 , A61K31/00 , A61K31/19 , A61K31/195 , A61K31/198 , A61K31/215 , A61P25/20 , A61P43/00 , C07C62/38 , C07C229/50 , C07D235/02 , A61K9/64
CPC分类号: C07D235/02 , A61K31/00 , A61K31/198 , A61K31/215 , C07C229/50 , C07C62/38 , C07C2102/18 , Y10S514/811 , Y10S514/82
摘要: The present invention provides a method of treating anxiety and related disorders using an agonist which acts at negatively coupled cAMP-linked metabotropic glutamate receptors.
摘要翻译: 本发明提供使用以负相关联的cAMP连接的代谢型谷氨酸受体作用的激动剂来治疗焦虑和相关疾病的方法。
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公开(公告)号:US06800651B2
公开(公告)日:2004-10-05
申请号:US10182961
申请日:2002-11-20
申请人: Darrell Stephen Coleman , Gunnar Erik Jagdmann , Kirk Willis Johnson , Michael Parvin Johnson , Thomas Hallett Large , James Allen Monn , Darryle Darwin Schoepp , Thomas Charles Britton , Steven Scott Henry , Joseph Patrick Tizzano
发明人: Darrell Stephen Coleman , Gunnar Erik Jagdmann , Kirk Willis Johnson , Michael Parvin Johnson , Thomas Hallett Large , James Allen Monn , Darryle Darwin Schoepp , Thomas Charles Britton , Steven Scott Henry , Joseph Patrick Tizzano
IPC分类号: A01K3144
CPC分类号: C07D213/40 , C07D213/30 , C07D213/38 , C07D213/42 , C07D213/61 , C07D213/643 , C07D213/76 , C07D213/89 , C07D405/12 , C07D409/12
摘要: The present invention relates to potentiators of metabotropic glutamate receptor function and specifically provides compounds of formula I, compositions thereof and methods of using the same.
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