公开(公告)号：US07892849B2

公开(公告)日：2011-02-22

申请号：US12389954

申请日：2009-02-20

申请人： David W. Burke ,  Michael Marquant ,  Udo Zapf ,  Michael Fritz ,  Dan Mosoiu ,  Chris Wilsey

发明人： David W. Burke ,  Michael Marquant ,  Udo Zapf ,  Michael Fritz ,  Dan Mosoiu ,  Chris Wilsey

IPC分类号： G01N33/48

CPC分类号： G01N33/558 ,  G01N27/3271 ,  Y10T156/1059 ,  Y10T156/1084

摘要： A test strip having a small sample-receiving chamber on the order of less than 1 microliter. The inventive test strip includes a reagent layer that extends across the width of the test strip and also extends to the sample-receiving end, such that the edges of the reagent layer are aligned with the side and dose receiving edges of the test strip. The hydrophilic reagent extending to the dosing edge of the strip promotes wicking of the sample into the test strip. The end and side edges of the reagent layer are preferably formed as part of a cutting process that forms individual test strips from a larger web, which results in a smooth and thin reagent layer with a uniform thickness, substantially covering the entire floor of the sample-receiving chamber. The inventive mass production process helps improve the reproducibility of the quantity, location, thickness and other properties of the reagent layer, which in turn improves the accuracy of the test result.

摘要翻译： 具有小于1微升量级的小样品接收室的测试条。 本发明的测试条包括跨越测试条的宽度延伸并且还延伸到样品接收端的试剂层，使得试剂层的边缘与测试条的侧面和剂量接收边缘对准。 延伸到条带的配量边缘的亲水试剂促进样品的芯吸到测试条中。 试剂层的端部和侧边缘优选形成为从较大纤维网形成单独的测试条的切割过程的一部分，其导致具有均匀厚度的平滑和薄的试剂层，基本覆盖样品的整个底板 接收室 本发明的批量生产方法有助于提高试剂层的数量，位置，厚度和其他性质的再现性，从而提高了测试结果的准确性。

公开(公告)号：US20090151864A1

公开(公告)日：2009-06-18

申请号：US12389954

申请日：2009-02-20

申请人： David W. Burke ,  Michael Marquant ,  Udo Zapf ,  Michael Fritz ,  Dan Mosoiu ,  Chris Wilsey

发明人： David W. Burke ,  Michael Marquant ,  Udo Zapf ,  Michael Fritz ,  Dan Mosoiu ,  Chris Wilsey

IPC分类号： B32B37/00

CPC分类号： G01N33/558 ,  G01N27/3271 ,  Y10T156/1059 ,  Y10T156/1084

摘要： A test strip having a small sample-receiving chamber on the order of less than 1 microliter. The inventive test strip includes a reagent layer that extends across the width of the test strip and also extends to the sample-receiving end, such that the edges of the reagent layer are aligned with the side and dose receiving edges of the test strip. The hydrophilic reagent extending to the dosing edge of the strip promotes wicking of the sample into the test strip. The end and side edges of the reagent layer are preferably formed as part of a cutting process that forms individual test strips from a larger web, which results in a smooth and thin reagent layer with a uniform thickness, substantially covering the entire floor of the sample-receiving chamber. The inventive mass production process helps improve the reproducibility of the quantity, location, thickness and other properties of the reagent layer, which in turn improves the accuracy of the test result.

摘要翻译： 具有小于1微升量级的小样品接收室的测试条。 本发明的测试条包括跨越测试条的宽度延伸并且还延伸到样品接收端的试剂层，使得试剂层的边缘与测试条的侧面和剂量接收边缘对准。 延伸到条带的配量边缘的亲水试剂促进样品的芯吸到测试条中。 试剂层的端部和侧边缘优选形成为从较大纤维网形成单独的测试条的切割过程的一部分，其导致具有均匀厚度的平滑和薄的试剂层，基本覆盖样品的整个底板 接收室 本发明的批量生产方法有助于提高试剂层的数量，位置，厚度和其他性质的再现性，从而提高了测试结果的准确性。

公开(公告)号：US07727467B2

公开(公告)日：2010-06-01

申请号：US10871673

申请日：2004-06-18

申请人： David W. Burke ,  Michael Marquant ,  Udo Zapf ,  Michael Fritz ,  Dan Mosoiu ,  Chris Wilsey

发明人： David W. Burke ,  Michael Marquant ,  Udo Zapf ,  Michael Fritz ,  Dan Mosoiu ,  Chris Wilsey

IPC分类号： G01N33/48

CPC分类号： G01N33/558 ,  G01N27/3271 ,  Y10T156/1059 ,  Y10T156/1084

摘要： A test strip having a small sample-receiving chamber on the order of less than 1 microliter. The inventive test strip includes a reagent layer that extends across the width of the test strip and also extends to the sample-receiving end, such that the edges of the reagent layer are aligned with the side and dose receiving edges of the test strip. The hydrophilic reagent extending to the dosing edge of the strip promotes wicking of the sample into the test strip. The end and side edges of the reagent layer are preferably formed as part of a cutting process that forms individual test strips from a larger web, which results in a smooth and thin reagent layer with a uniform thickness, substantially covering the entire floor of the sample-receiving chamber. The inventive mass production process helps improve the reproducibility of the quantity, location, thickness and other properties of the reagent layer, which in turn improves the accuracy of the test result.

摘要翻译： 具有小于1微升量级的小样品接收室的测试条。 本发明的测试条包括跨越测试条的宽度延伸并且还延伸到样品接收端的试剂层，使得试剂层的边缘与测试条的侧面和剂量接收边缘对准。 延伸到条带的配量边缘的亲水试剂促进样品的芯吸到测试条中。 试剂层的端部和侧边缘优选形成为从较大纤维网形成单独的测试条的切割过程的一部分，其导致具有均匀厚度的平滑和薄的试剂层，基本覆盖样品的整个底板 接收室 本发明的批量生产方法有助于提高试剂层的数量，位置，厚度和其他性质的再现性，从而提高了测试结果的准确性。

公开(公告)号：US20050016844A1

公开(公告)日：2005-01-27

申请号：US10871673

申请日：2004-06-18

申请人： David Burke ,  Michael Marquant ,  Udo Zapf ,  Michael Fritz ,  Dan Mosoiu ,  Chris Wilsey

发明人： David Burke ,  Michael Marquant ,  Udo Zapf ,  Michael Fritz ,  Dan Mosoiu ,  Chris Wilsey

IPC分类号： G01N27/26 ,  G01N31/22 ,  G01N33/00 ,  G01N33/487 ,  G01N33/558

CPC分类号： G01N33/558 ,  G01N27/3271 ,  Y10T156/1059 ,  Y10T156/1084

摘要： A test strip having a small sample-receiving chamber on the order of less than 1 microliter. The inventive test strip includes a reagent layer that extends across the width of the test strip and also extends to the sample-receiving end, such that the edges of the reagent layer are aligned with the side and dose receiving edges of the test strip. The hydrophilic reagent extending to the dosing edge of the strip promotes wicking of the sample into the test strip. The end and side edges of the reagent layer are preferably formed as part of a cutting process that forms individual test strips from a larger web, which results in a smooth and thin reagent layer with a uniform thickness, substantially covering the entire floor of the sample-receiving chamber. The inventive mass production process helps improve the reproducibility of the quantity, location, thickness and other properties of the reagent layer, which in turn improves the accuracy of the test result.

摘要翻译： 具有小于1微升量级的小样品接收室的测试条。 本发明的测试条包括跨越测试条的宽度延伸并且还延伸到样品接收端的试剂层，使得试剂层的边缘与测试条的侧面和剂量接收边缘对准。 延伸到条带的配量边缘的亲水试剂促进样品的芯吸到测试条中。 试剂层的端部和侧边缘优选形成为从较大纤维网形成单独的测试条的切割过程的一部分，其导致具有均匀厚度的平滑和薄的试剂层，基本覆盖样品的整个底板 接收室 本发明的批量生产方法有助于提高试剂层的数量，位置，厚度和其他性质的再现性，从而提高了测试结果的准确性。