Lipid vesicles formed with alkylammonium fatty acid salts
    3.
    发明授权
    Lipid vesicles formed with alkylammonium fatty acid salts 失效
    由烷基铵脂肪酸盐形成的脂质囊泡

    公开(公告)号:US5874105A

    公开(公告)日:1999-02-23

    申请号:US594175

    申请日:1996-01-31

    IPC分类号: A61K9/127

    CPC分类号: A61K9/1272

    摘要: A liposome for use in encapsulating both hydrophobic and hydrophilic substances (i.e., a "payload"),is disclosed which is capable of delivering their load upon the occurrence of a trigger or control condition. The liposomes are formed to stably encapsulate a particular active agent to form a delivery vehicle for the agent. The liposomes of the delivery vehicle are stable in a particular environment but become unstable or permeable if passed from the stable environment (e.g., characteristic of a particular pH and/or temperature and/or ionic strength) to a changed or unstable environment, thereby delivering their payload.

    摘要翻译: 公开了一种用于封装疏水和亲水物质(即“有效载荷”)的脂质体,其能够在发生触发或控制条件时传递其负载。 形成脂质体以稳定地包封特定的活性剂以形成药剂的递送载体。 递送载体的脂质体在特定环境中是稳定的,但是如果从稳定的环境(例如,特定的pH和/或温度和/或离子强度的特征)传递到改变或不稳定的环境,则其变得不稳定或可渗透,由此递送 他们的有效载荷。