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公开(公告)号：US11147537B2
公开(公告)日：2021-10-19
申请号：US16182715
申请日：2018-11-07
发明人： Nebojsa Duric , Peter Littrup , Cuiping Li , Olivier Roy , Steven Schmidt
摘要： A method and system for analyzing stiffness in a volume of tissue, the method including: emitting acoustic waveforms toward the volume of tissue with an array of ultrasound transmitters; detecting, with an array of ultrasound receivers, a set of acoustic signals derived from acoustic waveforms transmitted through the volume of tissue; generating, from the set of acoustic signals, a sound speed map and an acoustic attenuation map of a region of the volume of tissue, generating a stiffness map derived from combination of a set of sound speed parameter values of the sound speed map and a corresponding set of acoustic attenuation parameter values of the acoustic attenuation map, the stiffness map representing the distribution of the stiffness parameter across the region; and at a display in communication with the computer processor, rendering a stiffness image of the volume of tissue, based upon the stiffness map.
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公开(公告)号：US11064974B2
公开(公告)日：2021-07-20
申请号：US16155276
申请日：2018-10-09
发明人： James Szpak , Nebojsa Duric , Peter Littrup , Roman Janer , Mike Tesic
摘要： A patient interface system for scanning a volume of tissue protruding from a patient, the system comprising: a base including a planar portion configured to support the patient in a prone configuration, and a frustoconical portion extending from the planar portion and defining a base aperture configured to receive the volume of tissue; and a support assembly configured to couple to the base, including a frame and a membrane retained in tension within the frame at a peripheral portion of the membrane, wherein the membrane defines a membrane aperture configured to align with the base aperture, and wherein the membrane is configured to deflect into the frustoconical portion of the base in response to the patient's weight. The system can further include an electrical subsystem including a pressure sensor array configured to generate signals in response to a pressure distribution resulting from the patient's weight at the patient interface system.
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公开(公告)号：US20190083060A1
公开(公告)日：2019-03-21
申请号：US16123881
申请日：2018-09-06
发明人： Ron Ho , Peter Littrup , Nebojsa Duric
摘要： A tissue positioning system for contouring a patient tissue volume includes an axially displaceable interface having a surface configured to engage a breast or other tissue volume. A low pressure source applies a partial low pressure to the surface of the displaceable interface to secure the tissue volume to the surface, and the axially displaceable interface is biased to pull and contour the tissue volume when the tissue volume is secured to the surface. The axially displaceable interface is typically mounted on a telescoping support and the biasing is provided by the same low pressure used to secure the tissue volume.
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公开(公告)号：US10143443B2
公开(公告)日：2018-12-04
申请号：US14703746
申请日：2015-05-04
发明人： Nebojsa Duric , Peter Littrup , Cuiping Li , Olivier Roy , Steven Schmidt
摘要： A method and system for analyzing stiffness in a volume of tissue, the method including: emitting acoustic waveforms toward the volume of tissue with an array of ultrasound transmitters; detecting, with an array of ultrasound receivers, a set of acoustic signals derived from acoustic waveforms transmitted through the volume of tissue; generating, from the set of acoustic signals, a sound speed map and an acoustic attenuation map of a region of the volume of tissue, generating a stiffness map derived from combination of a set of sound speed parameter values of the sound speed map and a corresponding set of acoustic attenuation parameter values of the acoustic attenuation map, the stiffness map representing the distribution of the stiffness parameter across the region; and at a display in communication with the computer processor, rendering a stiffness image of the volume of tissue, based upon the stiffness map.
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公开(公告)号：US10123770B2
公开(公告)日：2018-11-13
申请号：US14208181
申请日：2014-03-13
发明人： James Szpak , Nebjosa Duric , Peter Littrup , Roman Janeer , Mike Tesic
摘要： A system for supporting a patient while scanning a volume of tissue protruding from a patient includes a base having a planar portion configured to support the patient in a prone configuration. A frustoconical portion extends from the planar portion and defines a base aperture configured to receive the volume of tissue. A support assembly couples to the base. A membrane is retained in tension within a frame at a peripheral portion of the membrane. The membrane defines a membrane aperture configured to align with the base aperture, and the membrane is configured to deflect into the frustoconical portion of the base in response to the patient's weight. The system can further include an electrical subsystem including a pressure sensor array configured to generate signals in response to a pressure distribution resulting from the patient's weight at the patient interface system.
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公开(公告)号：US11298111B2
公开(公告)日：2022-04-12
申请号：US16368986
申请日：2019-03-29
发明人： Nebojsa Duric , Peter Littrup , Cuiping Li
摘要： A method and system for generating an enhanced image of a volume of tissue, comprising: emitting acoustic waveforms toward the volume of tissue; detecting acoustic signals derived from acoustic waveforms interacting with the volume of tissue; generating a reflection rendering of a region of the volume of tissue; generating at least one of a sound speed map and an attenuation map of the region of the volume of tissue; generating a transfer map derived from a set of sound speed parameter values of the sound speed map and/or a set of acoustic attenuation parameter values of the acoustic attenuation map, the set of sound speed parameter values and the set of acoustic attenuation parameters associated with the set of elements of the region of the volume of tissue; and rendering an enhanced image of the volume of tissue, derived from processing of the reflection rendering with the transfer map.
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公开(公告)号：US10898164B2
公开(公告)日：2021-01-26
申请号：US15427857
申请日：2017-02-08
发明人： Ron Ho , Peter Littrup , Nebojsa Duric
摘要： A tissue positioning system for contouring a patient tissue volume includes an axially displaceable interface having a surface configured to engage a breast or other tissue volume. A low pressure source applies a partial low pressure to the surface of the displaceable interface to secure the tissue volume to the surface, and the axially displaceable interface is biased to pull and contour the tissue volume when the tissue volume is secured to the surface. The axially displaceable interface is typically mounted on a telescoping support and the biasing is provided by the same low pressure used to secure the tissue volume.
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公开(公告)号：US10201324B2
公开(公告)日：2019-02-12
申请号：US14486551
申请日：2014-09-15
发明人： Carri Glide-Hurst , Nebojsa Duric , Peter Littrup
摘要： A method for categorizing whole-breast density is disclosed. The method includes the steps of exposing breast tissue to an acoustic signal; measuring a distribution of an acoustic parameter by analyzing the acoustic signal; and obtaining a measure of whole-breast density from said measuring step. An apparatus is also disclosed.
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公开(公告)号：US20190038255A1
公开(公告)日：2019-02-07
申请号：US16155276
申请日：2018-10-09
发明人： James Szpak , Nebojsa Duric , Peter Littrup , Roman Janer , Mike Tesic
摘要： A patient interface system for scanning a volume of tissue protruding from a patient, the system comprising: a base including a planar portion configured to support the patient in a prone configuration, and a frustoconical portion extending from the planar portion and defining a base aperture configured to receive the volume of tissue; and a support assembly configured to couple to the base, including a frame and a membrane retained in tension within the frame at a peripheral portion of the membrane, wherein the membrane defines a membrane aperture configured to align with the base aperture, and wherein the membrane is configured to deflect into the frustoconical portion of the base in response to the patient's weight. The system can further include an electrical subsystem including a pressure sensor array configured to generate signals in response to a pressure distribution resulting from the patient's weight at the patient interface system.
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公开(公告)号：US20160038123A1
公开(公告)日：2016-02-11
申请号：US14819091
申请日：2015-08-05
发明人： Nebojsa Duric , Peter Littrup , Cuiping Li
CPC分类号： A61B8/5207 , A61B8/0825 , A61B8/085 , A61B8/14 , A61B8/15 , A61B8/406 , A61B8/4461 , A61B8/4477 , A61B8/4494 , A61B8/483 , A61B8/5246 , A61B8/5253 , G06T5/008 , G06T2207/10136 , G06T2207/30068
摘要： A method and system for generating an enhanced image of a volume of tissue, comprising: emitting acoustic waveforms toward the volume of tissue; detecting acoustic signals derived from acoustic waveforms interacting with the volume of tissue; generating a reflection rendering of a region of the volume of tissue; generating at least one of a sound speed map and an attenuation map of the region of the volume of tissue; generating a transfer map derived from a set of sound speed parameter values of the sound speed map and/or a set of acoustic attenuation parameter values of the acoustic attenuation map, the set of sound speed parameter values and the set of acoustic attenuation parameters associated with the set of elements of the region of the volume of tissue; and rendering an enhanced image of the volume of tissue, derived from processing of the reflection rendering with the transfer map.
摘要翻译： 一种用于产生组织体积增强的图像的方法和系统，包括：向组织体积发射声波形; 检测由与组织体积相互作用的声波导出的声信号; 产生组织体积的区域的反射渲染; 产生组织体积的区域的声速图和衰减图中的至少一个; 生成从声速图的一组声速参数值和/或声衰减图的一组声衰减参数值导出的传输图，声速参数值集合和与 组织体积的区域的一组元素; 并且通过传输图来渲染由反射渲染的处理导出的组织体积的增强图像。
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