摘要:
The invention provides novel substituted 6-arylamino pyridone carboxamides represented by Formula I, or a pharmaceutically acceptable salt, solvate, poly-morph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of MEK and are useful in the treatment of inflammatory diseases, cancer and other hyperproliferative diseases. The invention further provides a method of treatment for inflammatory diseases, cancer and other hyperproliferative diseases in mammals, especially humans.
摘要:
The invention provides novel substituted 6-arylamino pyridone carboxamides represented by Formula I, or a pharmaceutically acceptable salt, solvate, poly-morph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of MEK and are useful in the treatment of inflammatory diseases, cancer and other hyperproliferative diseases. The invention further provides a method of treatment for inflammatory diseases, cancer and other hyperproliferative diseases in mammals, especially humans.
摘要:
A scheduling method and apparatus for use by a processor that controls storage devices of a data storage system is presented. The method allocates processing time between I/O operations and background operations for predetermined time slots based on an indicator of processor workload.
摘要:
A scheduling method and apparatus for use by a processor that controls storage devices of a data storage system is presented. The method allocates processing time between I/O operations and background operations for predetermined time slots based on an indicator of processor workload.
摘要:
Described are techniques for representing and using RAID group consistency information. RAID group consistency information for a slice of data included on a device may be obtained by mapping the slice to an index. The index is one of a plurality of indices each associated with a structure indicating RAID group inconsistencies for a different portion of slices of data of the device. If the index is not associated with a structure, it may be determined that there is no RAID group inconsistency for the slice. If the index is associated with a structure, a hint bit associated with the slice may be determined wherein the hint bit encodes summary consistency information for a plurality of slices. A determination is made as to whether the hint bit is set, and, if the hint bit is not set, it is determined that there is no RAID group inconsistency for the slice.
摘要:
Scheduling jobs for a plurality of logical devices associated with physical devices includes assigning a physical run count value and a physical skip count value to each of the physical devices, at each iteration, examining the physical skip count value and the physical run count value for each of the physical devices, and scheduling a number of jobs up to the physical run count value for logical devices associated with a particular one of the physical devices at each iteration corresponding to the physical skip count value for the particular one of the physical devices. The physical skip count value and the physical run count value for a particular one of the physical devices may vary according to a total load of the particular physical device. The total load of the particular physical device may vary according to a number of jobs for all logical devices associated with the particular physical device and a total number of all jobs for all physical devices associated with a particular physical device controller.
摘要:
Scheduling jobs for a plurality of devices includes assigning a run count value to each of the devices, scheduling a number of consecutive jobs up to the run count value, and decrementing the run count value according to the number of consecutive jobs scheduled. The run count value for a particular one of the devices may vary according to a total load of the particular one of the devices. The total load of the particular device may vary according to a number of pending jobs for the particular device and a total number of jobs for all devices coupled to a controller for the devices. The devices may be disk drive devices. Only one read job may be scheduled for a device irrespective of the run count value for the device and devices having pending read jobs may be given precedence over other devices. Multiple read jobs may be scheduled for a device according to the run count value and devices having pending read jobs may be given precedence over other devices. The disk drive devices may be subdivided into a plurality of logical devices.
摘要:
Data units are prefetched into a cache memory by executing a first prefetch task to prefetch a first prefetch series of data units from off-cache. A first prefetch operation is executed to prefetch and store a first selected set of data units. Decisions are made about the first prefetch task, subsequent prefetch operations and prefetch tasks based on in-cache data units associated with the first prefetch task and on other data units that are read from off-cache but that are not associated with the first prefetch task. A determination is made whether an additional data unit that is read from an off-cache logical location is a first prefetch series member. If so, it is associated with the first prefetch task, and, for decision making, is treated as having been prefetched into cache in accordance with the first prefetch task.
摘要:
A cache management system and method monitors and controls the contents of cache memory coupled to at least one host and at least one data storage device where data-units are prefetched and stored into a cache memory in a data-set format, comprising the data-units and meta-data associated with the data units. The meta-data contain time stamp information encoded with information whether the cached prefetched information is available for reuse by additional prefetched data. Prefetched data-units are controlled by executing a first prefetch task to prefetch a first prefetch series of data-units from off-cache. A first prefetch operation is executed to prefetch and store a first selected set of data units. The prefetch task contains three dedicated pointers into cache memory. Decisions to prefetch data are made about the first prefetch task, subsequent prefetch operations and prefetch tasks based on these pointers, in-cache data-sets associated with the first prefetch task and on other data-sets that are read from off-cache but that are not associated with the first prefetch task. The cache management system and method reviews data-sets and controls the allocation and deallocation of space in the cache memory.
摘要:
Described are techniques for managing a sequential stream in a data storage system. A front-end component receives a plurality of data operations for a plurality of data portions and determines that the plurality of data portions are associated with a sequential stream. Each of the plurality of data portions of the sequential stream is associated with a sequential stream identifier, and a position indicator uniquely identifying a position of said each data portion in said sequential stream. Each of the plurality of data portions that is prefetched is associated with a remaining prefetched identifier and included in a prefetched chunk of data portions. The front-end component uses information about said sequential stream in connection with managing said sequential stream. The information includes the sequential stream identifier, one or more position indicators, and one or more remaining prefetched identifiers.