公开(公告)号：US20140109258A1

公开(公告)日：2014-04-17

申请号：US14022278

申请日：2013-09-10

Applicant: Devgen NV

Inventor： Marc Van De Craen ,  Geert Karel Maria Plaetinck ,  Isabel Vercauteren ,  Marc Georges Logghe ,  Thierry Andre Olivier Eddy Bogaert ,  Richard Zwaal

IPC: C12N15/113 ,  C12N15/82

CPC classification number: C12N15/8285 ,  C12N15/111 ,  C12N15/113 ,  C12N15/8279 ,  C12N2310/14 ,  C12N2310/3519 ,  C12N2330/30

Abstract: The present invention concerns concatemer and/or stabilized RNA constructs capable of forming dsRNA, optionally comprising a sequence capable of protecting the dsRNA against RNA processing in a host cell. The invention also relates to methods of producing these constructs and to methods for using these constructs. The constructs according to the present invention are particularly useful in plant pest control.

Abstract translation: 本发明涉及能够形成dsRNA的并联和/或稳定的RNA构建体，任选地包含能够保护dsRNA的宿主免受宿主细胞中RNA加工的序列。 本发明还涉及生产这些构建体的方法和使用这些构建体的方法。 根据本发明的构建体在植物害虫防治中特别有用。

公开(公告)号：US20190127756A1

公开(公告)日：2019-05-02

申请号：US15873065

申请日：2018-01-17

Applicant: DEVGEN NV

Inventor： Marc Van De Craen ,  Geert Karel Maria Plaetinck ,  Isabel Vercauteren ,  Marc Georges Logghe ,  Thierry Andre Olivier Eddy Bogaert ,  Richard Zwaal

IPC: C12N15/82 ,  C12N15/113 ,  C12N15/11

Abstract: The present invention concerns concatemer and/or stabilized RNA constructs capable of forming dsRNA, optionally comprising a sequence capable of protecting the dsRNA against RNA processing in a host cell. The invention also relates to methods of producing these constructs and to methods for using these constructs. The constructs according to the present invention are particularly useful in plant pest control.