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    Method for detecting a brain region with neurodegenerative change
    1.
    发明申请
    Method for detecting a brain region with neurodegenerative change 有权
    用于检测具有神经变性变化的脑区域的方法

    公开(公告)号：US20090030304A1

    公开(公告)日：2009-01-29

    申请号：US12219609

    申请日：2008-07-24

    申请人： Thorsten Feiweier ,  Diana Martin ,  Gunther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

    发明人： Thorsten Feiweier ,  Diana Martin ,  Gunther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

    IPC分类号： A61B5/055

    CPC分类号： A61K49/0004 ,  A61B5/4064 ,  A61B5/4088 ,  A61B6/037 ,  A61B6/5247

    摘要： A computerized method is disclosed for detecting a brain region with neurodegenerative change and also a brain region with vascular change in the brain of a patient and also an imaging arrangement suitable for this. In at least one embodiment, the method includes recording a first data record of the brain via positron emission tomography and a second data record of the brain via magnetic resonance imaging; reconstructing a PET image from the first data record and an MRI image from the second data record; identifying evidence for a brain region with vascular change in the MRI image; segmenting the MRI image into gray matter and white matter; identifying a brain region with neurodegenerative change in the PET image; and superposing the PET image and the segmented MRI image to determine whether the brain region with neurodegenerative change is present in gray matter or in white matter, the recording of the first data record and the second data record being carried out in quick succession without repositioning the patient or is even carried out simultaneously.

    摘要翻译： 公开了一种用于检测具有神经变性变化的脑区域以及患者脑部血管变化的脑区域的计算机化方法，以及适合于此的成像装置。 在至少一个实施例中，该方法包括通过正电子发射断层摄影和脑的第二数据记录经由磁共振成像记录脑的第一数据记录; 从第一数据记录重建PET图像和从第二数据记录重建MRI图像; 识别MRI图像中具有血管变化的脑区域的证据; 将MRI图像分割成灰质和白质; 识别PET图像中具有神经变性变化的脑区域; 并叠加PET图像和分割的MRI图像，以确定具有神经变性变化的脑区域是否存在于灰质物质或白质中，第一数据记录和第二数据记录的记录被快速连续进行而不重新定位 病人或甚至同时进行。

    Method and apparatus for imaging functional processes in the brain
    2.
    发明申请
    Method and apparatus for imaging functional processes in the brain 审中-公开
    用于成像脑功能过程的方法和装置

    公开(公告)号：US20090018431A1

    公开(公告)日：2009-01-15

    申请号：US12216293

    申请日：2008-07-02

    申请人： Thorsten Feiweier ,  Diana Martin ,  Gunther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

    发明人： Thorsten Feiweier ,  Diana Martin ,  Gunther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

    IPC分类号： A61B5/05

    CPC分类号： G01R33/481 ,  A61B5/0035 ,  A61B5/04008 ,  A61B5/4094 ,  A61B6/037 ,  A61B6/501 ,  A61B6/5247

    摘要： A method and an apparatus are disclosed for imaging functional processes in the brain. In order to be able to correlate the results of MEG examinations with anatomical information and metabolic data, a positron emission tomography measurement is recorded in at least one embodiment by at least one radiation detector, a magnetic resonance imaging measurement is recorded by a coil and a radio-frequency antenna device and a magnetoencephalography measurement is recorded by a plurality of magnetic field sensors, the positron emission tomography measurement and the magnetic resonance imaging measurement being substantially undertaken at the same time, so that the records of the positron emission tomography measurement and the magnetic resonance tomography measurement are isocentric. In at least one embodiment, an evaluation apparatus is provided for carrying out a spatial correlation between the magnetoencephalography measurement and the magnetic resonance imaging measurement, so that registration between the magnetoencephalography measurement and the positron emission tomography measurement results.

    摘要翻译： 公开了一种用于成像脑中的功能过程的方法和装置。 为了能够将MEG检查的结果与解剖信息和代谢数据相关联，在至少一个实施例中通过至少一个辐射检测器记录正电子发射断层摄影测量，磁共振成像测量由线圈和 射频天线装置和脑磁图测量由多个磁场传感器记录，正电子发射断层摄影测量和磁共振成像测量基本上同时进行，使得正电子发射断层摄影测量和 磁共振断层扫描测量是同中心的。 在至少一个实施例中，提供了一种用于执行脑磁图测量和磁共振成像测量之间的空间相关性的评估装置，从而导致脑磁图测量与正电子发射断层摄影测量之间的配准。

    Method for determining and displaying an access corridor to a target area in the brain of a patient
    3.
    发明申请
    Method for determining and displaying an access corridor to a target area in the brain of a patient 审中-公开
    用于确定和显示到患者脑中的目标区域的通道走廊的方法

    公开(公告)号：US20090005678A1

    公开(公告)日：2009-01-01

    申请号：US12213745

    申请日：2008-06-24

    申请人： Kristin Schmiedehausen ,  Gunther Platsch ,  Thorsten Feiweier ,  Diana Martin ,  Sebastian Schmidt ,  Michael Szimtenings

    发明人： Kristin Schmiedehausen ,  Gunther Platsch ,  Thorsten Feiweier ,  Diana Martin ,  Sebastian Schmidt ,  Michael Szimtenings

    IPC分类号： A61B6/03

    CPC分类号： A61B6/501 ,  A61B6/037 ,  A61B6/507 ,  A61B34/10 ,  A61B90/36 ,  A61B2090/364 ,  A61B2090/374

    摘要： A computer-implemented method is disclosed for determining and displaying an access corridor to a target area in the brain of a patient, as well as an imaging arrangement suited to this. In at least one embodiment, the method includes a) generating a first image of the brain via positron emission tomography, b) discriminating the target area relative to its surroundings via electronic image processing, c) generating a second image of the brain via magnetic resonance imaging while acquiring at least one anatomical structure, d) generating a third image of the brain via an imaging method displaying physiological processes for identifying at least one functional area of the brain that must not be injured in any circumstances, e) determining an access corridor to the target area while omitting the at least one functional area of the brain, and f) generating and displaying a fourth image of the brain in which the target area, the at least one functional area of the brain, the at least one anatomical structure and the access corridor are displayed, wherein steps a) to d) are carried out, one after another in quick succession, in a single frame of reference without repositioning the patient, or are even carried out simultaneously.

    摘要翻译： 公开了一种计算机实现的方法，用于确定和显示患者脑中的目标区域的通道走廊以及适合于此的成像装置。 在至少一个实施例中，该方法包括：a）通过正电子发射断层摄影术产生脑的第一图像，b）通过电子图像处理区分相对于其周围的目标区域，c）通过磁共振产生大脑的第二图像 成像，同时获取至少一个解剖结构，d）通过显示生理过程的成像方法产生大脑的第三图像，用于识别在任何情况下不得受伤的脑的至少一个功能区域，e）确定通路走廊 到目标区域，同时省略脑的至少一个功能区域，以及f）产生和显示脑的第四图像，其中目标区域，脑的至少一个功能区域，至少一个解剖结构 并且显示进入通道，其中步骤a）至d）在一个单独的参考框架中以快速连续的方式相继地执行而不重新定位 或者甚至同时进行。

    Method and apparatus for imaging functional and electrical activities of the brain
    4.
    发明申请
    Method and apparatus for imaging functional and electrical activities of the brain 审中-公开
    用于成像大脑功能和电活动的方法和装置

    公开(公告)号：US20090048507A1

    公开(公告)日：2009-02-19

    申请号：US12222210

    申请日：2008-08-05

    申请人： Thorsten Feiweier ,  Diana Martin ,  Gunther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

    发明人： Thorsten Feiweier ,  Diana Martin ,  Gunther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

    IPC分类号： A61B5/055 ,  A61B5/0476 ,  G01V3/00 ,  A61B6/00

    CPC分类号： A61B6/037 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/4094 ,  A61B6/032 ,  A61B6/501 ,  A61B6/5247 ,  G06T7/30

    摘要： A method and an apparatus for imaging functional and electrical activities of the brain are disclosed. In order to allow improved relative positional determination of the epileptogenic focus with reference to the EEG electrodes, a positron emission tomography measurement using at least one radiation detector, and a magnetic resonance imaging measurement using at least one coil for generating a basic magnetic field, at least one gradient coil and a radio-frequency antenna device are undertaken in at least one embodiment. In addition, in at least one embodiment an electroencephalography measurement using a plurality of electrodes for acquiring spatial and temporal changes of the electrical activities of the brain and a computed tomography measurement using at least one x-ray source and at least one x-ray detector are carried out. By way of an evaluation apparatus in at least one embodiment, a spatial correlation between the computed tomography measurement and the magnetic resonance imaging measurement is undertaken, so as to result in registration between the electroencephalography measurement and the positron emission tomography measurement.

    摘要翻译： 公开了一种用于成像大脑的功能和电活动的方法和装置。 为了允许参考EEG电极改进癫痫发生焦点的相对位置确定，使用至少一个辐射检测器的正电子发射断层摄影测量和使用至少一个线圈产生基本磁场的磁共振成像测量，在 至少一个实施例中进行至少一个梯度线圈和射频天线装置。 另外，在至少一个实施例中，使用多个电极获取脑的电活动的空间和时间变化以及使用至少一个X射线源和至少一个X射线检测器的计算机断层摄影测量的脑电图测量 被执行。 通过至少一个实施例中的评估装置，进行计算机断层摄影测量和磁共振成像测量之间的空间相关性，以便导致脑电图测量与正电子发射断层摄影测量之间的对准。