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公开(公告)号：US09458487B2
公开(公告)日：2016-10-04
申请号：US11400840
申请日：2006-04-07
申请人： Diane M. Retallack , Charles H. Squires , David C. Watkins , Stacey L. Lee , Frank H. Gaertner , Robert Shutter
发明人： Diane M. Retallack , Charles H. Squires , David C. Watkins , Stacey L. Lee , Frank H. Gaertner , Robert Shutter
CPC分类号： C12P21/00 , C07K14/52 , C07K14/57 , C07K14/61 , C07K16/40 , C07K2317/14 , C07K2317/622 , C12N15/78 , C12P21/02 , C12Y302/01023
摘要： The invention is a process for improved production of a recombinant mammalian protein by expression in a Pseudomonad, particularly in a Pseudomonas fluorescens organism. The process improves production of mammalian proteins, particularly human or human-derived proteins, over known expression systems such as E. coli in comparable circumstances Processes for improved production of isolated mammalian, particularly human, proteins are provided.
摘要翻译： 本发明是通过在假单胞菌，特别是荧光假单胞菌生物体中表达来改进重组哺乳动物蛋白质生产的方法。 该方法在可比较的情况下，通过已知的表达系统如大肠杆菌改善了哺乳动物蛋白质，特别是人源或人源蛋白质的产生。提供了分离的哺乳动物，特别是人类蛋白质的改进生产的方法。
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公开(公告)号：US09453251B2
公开(公告)日：2016-09-27
申请号：US11038901
申请日：2005-01-18
申请人： Diane M. Retallack , Charles H. Squires , David C. Watkins , Stacey L. Lee , Frank H. Gaertner , Robert Shutter
发明人： Diane M. Retallack , Charles H. Squires , David C. Watkins , Stacey L. Lee , Frank H. Gaertner , Robert Shutter
CPC分类号： C12P21/00 , C07K14/52 , C07K14/57 , C07K14/61 , C07K16/40 , C07K2317/14 , C07K2317/622 , C12N15/78 , C12P21/02 , C12Y302/01023
摘要： The invention is a process for improved production of a recombinant mammalian protein by expression in a Pseudomonad, particularly in a Pseudomonas fluorescens organism. The process improves production of mammalian proteins, particularly human or human-derived proteins, over known expression systems such as E. coli in comparable circumstances Processes for improved production of isolated mammalian, particularly human, proteins are provided.
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公开(公告)号：US20060234346A1
公开(公告)日：2006-10-19
申请号：US11400840
申请日：2006-04-07
申请人： Diane Retallack , Charles Squires , David Watkins , Stacey Lee , Frank Gaertner , Robert Shutter
发明人： Diane Retallack , Charles Squires , David Watkins , Stacey Lee , Frank Gaertner , Robert Shutter
CPC分类号： C12P21/00 , C07K14/52 , C07K14/57 , C07K14/61 , C07K16/40 , C07K2317/14 , C07K2317/622 , C12N15/78 , C12P21/02 , C12Y302/01023
摘要： The invention is a process for improved production of a recombinant mammalian protein by expression in a Pseudomonad, particularly in a Pseudomonas fluorescens organism. The process improves production of mammalian proteins, particularly human or human-derived proteins, over known expression systems such as E. coli in comparable circumstances Processes for improved production of isolated mammalian, particularly human, proteins are provided.
摘要翻译： 本发明是通过在假单胞菌，特别是荧光假单胞菌生物体中表达来改进重组哺乳动物蛋白质生产的方法。 该方法在可比较的情况下，通过已知的表达系统如大肠杆菌改善了哺乳动物蛋白质，特别是人源或人源蛋白质的产生。提供了分离的哺乳动物，特别是人类蛋白质的改进生产的方法。
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公开(公告)号：US20060040352A1
公开(公告)日：2006-02-23
申请号：US11038901
申请日：2005-01-18
申请人： Diane Retallack , Charles Squires , David Watkins , Stacey Lee , Frank Gaertner , Robert Shutter
发明人： Diane Retallack , Charles Squires , David Watkins , Stacey Lee , Frank Gaertner , Robert Shutter
CPC分类号： C12P21/00 , C07K14/52 , C07K14/57 , C07K14/61 , C07K16/40 , C07K2317/14 , C07K2317/622 , C12N15/78 , C12P21/02 , C12Y302/01023
摘要： The invention is a process for improved production of a recombinant mammalian protein by expression in a Pseudomonad, particularly in a Pseudomonas fluorescens organism. The process improves production of mammalian proteins, particularly human or human-derived proteins, over known expression systems such as E. coli in comparable circumstances Processes for improved production of isolated mammalian, particularly human, proteins are provided.
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