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公开(公告)号：US20140051063A1
公开(公告)日：2014-02-20
申请号：US14114509
申请日：2012-04-26
IPC分类号： A01N1/02
CPC分类号： A01N1/0226 , G01N33/96 , G01N2333/765
摘要： The present specification provides hematology control compositions having particular utility with a red blood cell component for devices using electronic and optical means for blood determinations, and methods for using the compositions.
摘要翻译： 本说明书提供具有用于使用电子和光学手段用于血液测定的装置的红血细胞组分的特殊用途的血液学控制组合物，以及使用该组合物的方法。
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2.发明授权Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement 有权无氰溶剂试剂组合物及血红蛋白和白细胞测定方法公开(公告)号：US07235404B2
公开(公告)日：2007-06-26
申请号：US11125395
申请日：2005-05-04
CPC分类号： G01N33/721 , Y10T436/10 , Y10T436/101666 , Y10T436/107497 , Y10T436/25
摘要： A cyanide-free lytic reagent composition and method of use for measuring the total hemoglobin concentration and white blood cells in a blood sample are disclosed. The lytic reagent composition includes a quaternary ammonium surfactant to lyse red blood cells and release hemoglobin and a ligand to form a stable chromogen with the hemoglobin. The lytic reagent composition has a pH in a range of 3 to 10. The lytic reagent composition can also include a second quaternary ammonium surfactant. The ligand can be malic acid, malonic acid, ethylene diamine, N,N-diethylethylene diamine, N,N′-diethylethylene diamine, diethylene triamine, tetraethylene pentamine, 1,6-hexanediamine, 1,3-pentanediamine, 2-methylpentamethylenediamine, 1,2-diaminocyclohexane, 4-aminoacetophenone, bis-hexamethylenetriamine, pyridazine, or 3,6-dihyroxypyridazine.
摘要翻译： 公开了一种无氰溶解试剂组合物和用于测量血液样品中总血红蛋白浓度和白细胞的方法。 溶解试剂组合物包括季铵表面活性剂以溶解红细胞并释放血红蛋白和配体以与血红蛋白形成稳定的色原体。 溶解试剂组合物的pH值在3至10的范围内。裂解试剂组合物还可包括第二季铵表面活性剂。 配体可以是苹果酸，丙二酸，乙二胺，N，N-二乙基乙二胺，N，N'-二乙基乙二胺，二亚乙基三胺，四亚乙基五胺，1,6-己二胺，1,3-戊二胺，2-甲基戊二胺， 1,2-二氨基环己烷，4-氨基苯乙酮，双六亚甲基三胺，哒嗪或3,6-二羟基哒嗪。
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3.发明申请Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement 有权无氰溶剂试剂组合物及血红蛋白和白细胞测定方法公开(公告)号：US20060263889A1
公开(公告)日：2006-11-23
申请号：US11125395
申请日：2005-05-04
IPC分类号： G01N33/72
CPC分类号： G01N33/721 , Y10T436/10 , Y10T436/101666 , Y10T436/107497 , Y10T436/25
摘要： A cyanide-free lytic reagent composition and method of use for measuring the total hemoglobin concentration and white blood cells in a blood sample are disclosed. The lytic reagent composition includes a quaternary ammonium surfactant to lyse red blood cells and release hemoglobin and a ligand to form a stable chromogen with the hemoglobin. The lytic reagent composition has a pH in a range of 3 to 10. The lytic reagent composition can also include a second quaternary ammonium surfactant. The ligand can be malic acid, malonic acid, ethylene diamine, N,N-diethylethylene diamine, N,N′-diethylethylene diamine, diethylene triamine, tetraethylene pentamine, 1,6-hexanediamine, 1,3-pentanediamine, 2-methylpentamethylenediamine, 1,2-diaminocyclohexane, 4-aminoacetophenone, bis-hexamethylenetriamine, pyridazine, or 3,6-dihyroxypyridazine.
摘要翻译： 公开了一种无氰溶解试剂组合物和用于测量血液样品中总血红蛋白浓度和白细胞的方法。 溶解试剂组合物包括季铵表面活性剂以溶解红细胞并释放血红蛋白和配体以与血红蛋白形成稳定的色原体。 溶解试剂组合物的pH值在3至10的范围内。裂解试剂组合物还可包括第二季铵表面活性剂。 配体可以是苹果酸，丙二酸，乙二胺，N，N-二乙基乙二胺，N，N'-二乙基乙二胺，二亚乙基三胺，四亚乙基五胺，1,6-己二胺，1,3-戊二胺，2-甲基戊二胺， 1,2-二氨基环己烷，4-氨基苯乙酮，双六亚甲基三胺，哒嗪或3,6-二羟基哒嗪。
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