Analytical system and method for analyzing nonlinear optical signals
    2.
    发明授权
    Analytical system and method for analyzing nonlinear optical signals 失效
    用于分析非线性光信号的分析系统和方法

    公开(公告)号:US07545494B2

    公开(公告)日:2009-06-09

    申请号:US10565909

    申请日:2003-07-01

    IPC分类号: G01N21/64

    摘要: A method for the ultrasensitive simultaneous measurement of nonlinear optical emission signals in one or two local dimensions wherein excitation light is irradiated in modulated form from at least one light source into an interactive space in which one or several emissions that are nonlinearly correlated with the excitement light can be excited. The light emanating from the interactive spaces is measured using a one or two-dimensional detector array. Measured data is then transmitted to a computer and formatted in a one or two-dimensional data matrix. Further, non-correlated portions of the light emanating from the interactive spaces that are linearly proportionate to the intensity of the excitement light available in the interactive spaces are separated from portions of the light emanating from the interactive spaces which are not linearly proportionate. The invention also relates to an analytical system for carrying out this method.

    摘要翻译: 一种用于在一个或两个局部维度中的非线性光发射信号的超灵敏同时测量的方法,其中激发光以调制形式从至少一个光源照射到相互作用空间中,其中一个或多个与兴奋光非线性相关的发射 可以兴奋 使用一维或二维检测器阵列测量从交互空间发出的光。 然后将测量的数据发送到计算机并以一维或二维数据矩阵格式化。 此外,与交互空间中可用的兴奋光的强度成线性成比例的从交互空间发出的光的非相关部分与从交互空间发出的光不是线性成比例的部分分离。 本发明还涉及一种用于实施该方法的分析系统。

    Analytical system and method for analyzing nonlinear optical signals
    3.
    发明申请
    Analytical system and method for analyzing nonlinear optical signals 失效
    用于分析非线性光信号的分析系统和方法

    公开(公告)号:US20060291772A1

    公开(公告)日:2006-12-28

    申请号:US10565909

    申请日:2003-07-01

    IPC分类号: G02B6/26

    摘要: The invention relates to a method for the ultrasensitive simultaneous measurement of nonlinear optical emission signals in one or two local dimensions. Said method comprises the following steps: the excitation light is irradiated in a power-modulated or pulse-modulated form from at least one light source into an interactive volume or onto an interactive area or layer (hereafter called interactive spaces) in which one or several emissions that are nonlinearly correlated with the excitement light can be excited; the light emanating from said interactive spaces is measured by means of a one-dimensional or two-dimensional detector array; the measured data is transmitted from said detector array to a computer, and said data is formatted in a one-dimensional or two-dimensional data matrix. The inventive method is characterized in that non-correlated portions of the light emanating from the interactive spaces or the portions thereof that are linearly proportionate to the intensity of the excitement light available in said interactive spaces are separated from portions of the light emanating from the interactive spaces, which are not linearly proportionate to the intensity of the available excitement light. The invention further relates to an analytical system that is suitable for carrying out the inventive method.

    摘要翻译: 本发明涉及用于在一个或两个局部维度上的非线性光发射信号的超灵敏同时测量的方法。 所述方法包括以下步骤:将激发光以功率调制或脉冲调制形式从至少一个光源照射到交互式卷或交互式区域或层(以下称为交互空间),其中一个或几个 可以激发与兴奋光线非线性相关的排放; 通过一维或二维检测器阵列测量从所述交互空间发出的光; 测量数据从所述检测器阵列发送到计算机,并且所述数据被格式化为一维或二维数据矩阵。 本发明的方法的特征在于,从与交互空间中可用的兴奋光的强度成线性成比例的交互空间或其部分发出的光的非相关部分与从交互式中发出的光的部分分离 空间,其与可用的兴奋光的强度不成线性比例。 本发明还涉及适用于实施本发明方法的分析系统。

    Grating waveguide structure for reinforcing an excitation field and use thereof
    4.
    发明申请
    Grating waveguide structure for reinforcing an excitation field and use thereof 审中-公开
    用于加强激励场的光栅波导结构及其用途

    公开(公告)号:US20090224173A1

    公开(公告)日:2009-09-10

    申请号:US12318568

    申请日:2008-12-31

    IPC分类号: G01J1/58 G02F1/01

    摘要: The invention relates to a variable embodiment of a grating waveguide structure, based on a planar thin-film waveguide with a first optically transparent layer (a) on a second optically transparent layer (b) having a lower refractive index than layer (a), and a grating structure (c) modulated in layer (a), wherein the intensity of an excitation light irradiated at the resonance angle for incoupling into layer (a) is enhanced by at least a factor of 100 on layer (a) and within layer (a), at least in the region of the grating structure (c), in comparison with the intensity of said excitation light on a substrate surface without incoupling of the excitation light. The invention also relates to an optical system with an excitation light source and an embodiment of a grating waveguide structure according to the invention, and to a method for enhancing an excitation light intensity, and to the use thereof in bioanalytical detection processes, in non-linear optics or in telecommunications or communications industry.

    摘要翻译: 本发明涉及一种基于具有比层(a)折射率低的第二光学透明层(b)上具有第一光学透明层(a)的平面薄膜波导的光栅波导结构的可变实施例, 以及在层(a)中调制的光栅结构(c),其中以共耦合角度照射到层(a)中的激发光的强度在层(a)上至少增加100倍,并且在层 (a),至少在光栅结构(c)的区域中,与衬底表面上的所述激发光的强度相比较,而不会激发激发光的耦合。 本发明还涉及具有激发光源和根据本发明的光栅波导结构的实施例的光学系统,以及用于增强激发光强度的方法及其在生物分析检测过程中的用途, 线性光学或电信或通信行业。

    Method and device for measuring luminescence
    5.
    发明授权
    Method and device for measuring luminescence 有权
    用于测量发光的方法和装置

    公开(公告)号:US06710870B1

    公开(公告)日:2004-03-23

    申请号:US09601484

    申请日:2000-08-03

    IPC分类号: G01J330

    摘要: A method exites and determines a luminescence in an analyte sample which is located in contact with the waveguiding layer of an optical layer waveguide. The luminescence is generated by non-evanescent excitation in the volume of the analyte sample. Luminescence radiation generated in the immediate proximity of the surface of the waveguiding layer is conducted to a measuring device and determined after penetrating the waveguiding layer.

    摘要翻译: 一种方法显示和确定位于与光学层波导的波导层接触的分析物样品中的发光。 通过在分析物样品的体积中的非消逝激发产生发光。 在波导层的表面附近产生的发光辐射被传导到测量装置,并在穿透波导层之后确定。