公开(公告)号：US20090170932A1

公开(公告)日：2009-07-02

申请号：US12347073

申请日：2008-12-31

Applicant: Dinesh AGGARWAL ,  Chirag Shah

Inventor： Dinesh AGGARWAL ,  Chirag Shah

IPC: A61K31/375 ,  A61L2/18

CPC classification number: A61K31/375 ,  A01N41/12 ,  A61L2/18 ,  A61L12/14 ,  A01N43/08 ,  A01N2300/00

Abstract: Disinfectant compositions comprising N-Acetyl Cysteine (NAC) and Vitamin C are disclosed. The disinfectant compositions have also demonstrated activity in inhibiting as well as killing micro-organisms responsible for generating biofilms. They are safe for human and medical uses and may be used as prophylactic preparations to reduce the proliferation of and/or eliminate existing or established infections.

Abstract translation: 公开了包含N-乙酰半胱氨酸（NAC）和维生素C的消毒剂组合物。 消毒剂组合物还显示了抑制和杀死负责产生生物膜的微生物的活性。 它们对于人类和医学用途是安全的，并且可以用作预防剂，以减少现有或已建立的感染的增殖和/或消除现有或已建立的感染。

公开(公告)号：US20190021321A1

公开(公告)日：2019-01-24

申请号：US16070351

申请日：2017-02-28

Applicant: Dinesh AGGARWAL

Inventor： Dinesh AGGARWAL

IPC: A01N37/44 ,  A01N31/02 ,  A61L29/16

Abstract: To reduce problems associated with clotting and thrombus formation, it is now common to “lock” intravascular access catheters between successive uses. Locking typically involves first flushing the catheter with saline to remove blood and other substances from the catheter lumen. After the catheter has been flushed, an anti-coagulant solution is injected to displace the saline and fill the lumen. Use of an effective antimicrobial substance along with anticoagulant during the same process is important to reduce the possibility of bacterial contamination and subsequent infection. The present invention deals with a safe, effective and economical catheter lock flush solution with excellent antimicrobial and anticoagulant activity. The unique ratio of the active components of the catheter lock solution used in the invention i.e. Sodium salt(s) of EDTA, Ethanol and D-mannitol with a suitable pH ensures broad-spectrum antimicrobial and optimum anticoagulant activity.