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公开(公告)号:US07052850B2
公开(公告)日:2006-05-30
申请号:US10084507
申请日:2002-02-28
申请人: Donald G. Munroe , Rajender Kamboj , Diana Peters , Fatemeh Kooshesh , Tejal B. Vyas , Ashwani K. Gupta
发明人: Donald G. Munroe , Rajender Kamboj , Diana Peters , Fatemeh Kooshesh , Tejal B. Vyas , Ashwani K. Gupta
IPC分类号: G01N33/53 , G01N33/566 , C12N5/00 , C12N15/00 , C07K14/705
CPC分类号: C07K14/705 , A61K38/00
摘要: A novel, isolated EDG receptor that upon activation results in increased induction of IL-8 or NF-κB. Preferably, the EDG receptor is a human EDG-4 receptor, which has an amino acid sequence shown in FIGS. 16A and 16B, or a variant of these sequences having at least 91% sequence identity.
摘要翻译: 一种新型的分离的EDG受体,其在激活时导致IL-8或NF-κB的诱导增加。 优选地,EDG受体是人EDG-4受体,其具有图1和图2所示的氨基酸序列。 16 A和16 B,或这些序列的变体具有至少91%的序列同一性。