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1.发明授权Formulations for dyeing keratin fibers comprising a pyrazolotriazole coupler and oxidation base 失效用于染色角蛋白纤维的制剂，其包含吡唑并三唑成色剂和氧化碱公开(公告)号：US06197071B1
公开(公告)日：2001-03-06
申请号：US09416823
申请日：1999-10-12
IPC分类号： A61K713
CPC分类号： G03C7/3212 , C09B55/003
摘要： Formulations for the oxidation dyeing of keratin fibers comprising a coupler and oxidation base. The couplers are represented by the following structure: wherein: Z represents the elements of C, N, O, or S necessary to complete a substituted or unsubstituted heterocyclic 5 or 6 member ring along with nitrogen; R1 represents a substituent group; and, X represents a hydrogen or a coupling off group.
摘要翻译： 用于包含偶联剂和氧化碱的角蛋白纤维的氧化染色的制剂。 成色剂由以下结构表示：其中：Z表示与氮一起完成取代或未取代的杂环5或6元环所需的C，N，O或S的元素; R 1表示取代基; X 表示氢或偶合离去基团。
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公开(公告)号：US6140033A
公开(公告)日：2000-10-31
申请号：US218511
申请日：1998-12-22
CPC分类号： G03C7/3212 , C09B55/003
摘要： A photographic element comprises novel pyrazolo[5,1-c]-1,2,4-triazole dye forming couplers, the couplers and azomethine dyes. The couplers are represented by the following structure: ##STR1## wherein: Z represents the elements of C, N, O, or S necessary to complete a substituted or unsubstituted heterocyclic 5 or 6 member ring along with nitrogen;R.sub.1 represents a substituent group;and, X represents a hydrogen or a coupling off group.
摘要翻译： 照相元件包括新型吡唑并[5,1-c] -1,2,4-三唑染料形成成色剂，成色剂和偶氮甲碱染料。 成色剂由以下结构表示：其中：Z表示与氮一起完成取代或未取代的杂环5或6元环所必需的C，N，O或S的元素; R1表示取代基; X表示氢或偶合离去基团。
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公开(公告)号：US06521397B1
公开(公告)日：2003-02-18
申请号：US10122284
申请日：2002-04-12
IPC分类号： G03C146
CPC分类号： G03C7/381 , G03C7/3815 , G03C7/382
摘要： Disclosed is a photographic element comprising a support bearing a light sensitive silver halide emulsion layer having associated therewith a dye forming coupler having a formula I, wherein: Ballast is a group containing at least 6 aliphatic carbon atoms, V represents a chain of three or four atoms, which may be substituted, selected from C, N, O and S sufficient to form an aromatic ring fused to the azole ring and n is 0 or 1, provided that if n is 0, Y and Ballast are directly attached to the 5-membered azole ring, W is an electron withdrawing group selected from the group consisting of —CN, —CONR1R2, —CO2R1, —NO2, and —SO2R1 where R1 and R2 are H or substituents; X is H or a coupling-off group; Y is H or a substituent; Z is an atom or group selected from >N—R, —O—, and —S—.
摘要翻译： 公开了一种照相元件，其包括带有光敏卤化银乳剂层的载体，其具有式I的染料形成成色剂，其中：镇流器是含有至少6个脂族碳原子的基团，V表示三或四条链 原子，其可以被选自C，N，O和S，足以形成与唑环稠合的芳环，n为0或1，条件是如果n为0，则Y和镇流器直接连接到5 W是选自-CN，-CONR1R2，-CO2R1，-NO2和-SO2R1的吸电子基团，其中R 1和R 2是H或取代基; X是H或偶联离去基团 Y为H或取代基; Z为选自NR，-O-和-S-的原子或基团。
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公开(公告)号：US20120041546A1
公开(公告)日：2012-02-16
申请号：US13202357
申请日：2010-02-19
CPC分类号： A61L17/10 , A61L17/105 , A61L17/12 , A61L27/18 , A61L27/50 , A61L31/06 , A61L31/14 , C08J7/123 , Y10T428/31504 , Y10T428/3154 , Y10T428/31551 , Y10T428/31663 , Y10T428/31725 , Y10T428/31855 , C08L67/04
摘要： Implantable biocompatible polymeric medical devices include a substrate with a plasma-modified surface which is subsequently modified to include click reactive members.
摘要翻译： 植入式生物相容性聚合物医疗装置包括具有等离子体改性表面的基底，其随后被修改以包括点击反应性构件。
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公开(公告)号：US20110123476A1
公开(公告)日：2011-05-26
申请号：US13012833
申请日：2011-01-25
申请人： Mbiya Kapiamba , Ahmad Robert Hadba
发明人： Mbiya Kapiamba , Ahmad Robert Hadba
CPC分类号： A61L24/04 , A61L24/046 , A61L26/0019 , C08L71/02
摘要： The disclosure relates to biocompatible components useful for forming compositions for use as medical/surgical synthetic adhesives and sealants. Biocompatible components of the present disclosure may include a multifunctional amine or multifunctional polyol core, with isocyanate and/or polyalkylene oxide arms, which may optionally be capped with electrophilic or nucleophilic groups. These biocompatible components may, in embodiments, be combined with optional cross linkers to form adhesive and/or sealant compositions.
摘要翻译： 本公开涉及可用于形成用作医疗/外科合成粘合剂和密封剂的组合物的生物相容性组分。 本公开的生物相容性组分可以包括具有异氰酸酯和/或聚环氧烷臂的多官能胺或多官能多元醇芯，其可任选地被亲电或亲核基团封端。 在实施方案中，这些生物相容性组分可与任选的交联剂组合以形成粘合剂和/或密封剂组合物。
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公开(公告)号：US08349987B2
公开(公告)日：2013-01-08
申请号：US12698216
申请日：2010-02-02
申请人： Mbiya Kapiamba , Jack Kennedy , Roland Ostapoff
发明人： Mbiya Kapiamba , Jack Kennedy , Roland Ostapoff
IPC分类号： C08G18/00 , C08G18/08 , C08G63/00 , C08G73/00 , A61K31/74 , C08F283/04 , C09J4/00 , C09J101/00 , C09J201/00
CPC分类号： C08G65/337 , C08G65/3322 , C08G65/3326 , C08G65/33306 , C08G65/33389 , C08L2203/02
摘要： The disclosure relates to biocompatible components useful for forming compositions for use as medical/surgical synthetic adhesives and sealants. Biocompatible components of the present disclosure may include a polymeric polyol core, which may be treated with a nitroaryl compound to form a nitro ester. The resulting nitro ester groups may be reduced to form amino groups which, in turn, may be treated to form isocyanate groups. The resulting isocyanate may then be reacted with a second component to form adhesive and/or sealant compositions.
摘要翻译： 本公开涉及可用于形成用作医疗/外科合成粘合剂和密封剂的组合物的生物相容性组分。 本公开的生物相容性组分可以包括聚合多元醇核心，其可以用硝基芳基化合物处理以形成硝基酯。 所得到的硝基酯基团可以还原形成氨基，其又可以被处理以形成异氰酸酯基团。 然后可将得到的异氰酸酯与第二组分反应形成粘合剂和/或密封剂组合物。
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公开(公告)号：US08034396B2
公开(公告)日：2011-10-11
申请号：US12368415
申请日：2009-02-10
申请人： Mbiya Kapiamba , Nadya Belcheva
发明人： Mbiya Kapiamba , Nadya Belcheva
CPC分类号： A61L24/043
摘要： The present disclosure provides compositions which may be utilized as adhesives or sealants in medical and surgical applications. The compositions may, in embodiments, be formed from the cycloaddition reaction of a first component possessing at least one azide group with a second component possessing at least one alkyne group.
摘要翻译： 本公开提供了可用作医疗和外科应用中的粘合剂或密封剂的组合物。 在实施方案中，组合物可以由具有至少一个叠氮基的第一组分与具有至少一个炔基的第二组分的环加成反应形成。
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公开(公告)号：US08968818B2
公开(公告)日：2015-03-03
申请号：US13202373
申请日：2010-02-19
IPC分类号： A61L33/06 , B05D3/00 , C08J7/14 , C08J7/12 , A61L33/04 , A61L31/14 , A61L31/04 , A61F2/06 , A61F2/50 , A61F13/00
CPC分类号： C08J7/12 , A61L31/04 , A61L31/042 , A61L31/043 , A61L31/044 , A61L31/048 , A61L31/06 , A61L31/14 , A61L31/148 , A61L31/16 , A61L33/06 , A61L2400/18 , C08J7/14 , C08J2300/16 , Y10T442/20
摘要： Implantable biocompatible polymeric medical devices include a substrate with an acid or base-modified surface which is subsequently modified to include click reactive members.
摘要翻译： 植入式生物相容性聚合物医疗装置包括具有酸或碱改性表面的基底，其随后被修改以包括点击反应性构件。
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公开(公告)号：US20100209380A1
公开(公告)日：2010-08-19
申请号：US12698216
申请日：2010-02-02
申请人： Mbiya Kapiamba , Jack Kennedy , Roland Ostapoff
发明人： Mbiya Kapiamba , Jack Kennedy , Roland Ostapoff
IPC分类号： C07C263/10 , C07C265/12 , C08G18/32 , B32B37/12 , A61K31/74 , A61P17/02
CPC分类号： C08G65/337 , C08G65/3322 , C08G65/3326 , C08G65/33306 , C08G65/33389 , C08L2203/02
摘要： The disclosure relates to biocompatible components useful for forming compositions for use as medical/surgical synthetic adhesives and sealants. Biocompatible components of the present disclosure may include a polymeric polyol core, which may be treated with a nitroaryl compound to form a nitro ester. The resulting nitro ester groups may be reduced to form amino groups which, in turn, may be treated to form isocyanate groups. The resulting isocyanate may then be reacted with a second component to form adhesive and/or sealant compositions.
摘要翻译： 本公开涉及可用于形成用作医疗/外科合成粘合剂和密封剂的组合物的生物相容性组分。 本公开的生物相容性组分可以包括聚合多元醇核心，其可以用硝基芳基化合物处理以形成硝基酯。 所得到的硝基酯基团可以还原形成氨基，其又可以被处理以形成异氰酸酯基团。 然后可将得到的异氰酸酯与第二组分反应形成粘合剂和/或密封剂组合物。
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公开(公告)号：US20100087668A1
公开(公告)日：2010-04-08
申请号：US12502723
申请日：2009-07-14
申请人： Mbiya Kapiamba
发明人： Mbiya Kapiamba
IPC分类号： C07C227/04
CPC分类号： C07C217/84 , C08G65/322 , C08G65/3326 , C08G65/33386 , C08K5/175
摘要： The present disclosure provides for the synthesis of branched polyamines. In embodiments, branched polyamines may be formed by reacting a branched polyol with a nitroaryl carboxylic acid to form a nitrobenzoyl ester which, in turn, may then be subjected to a hydrogenating step to form the branched polyamine. The resulting branched polyamine may then be reacted with another hydrogel precursor to form a hydrogel.
摘要翻译： 本公开内容提供了支链多胺的合成。 在实施方案中，支化多胺可以通过使支化多元醇与硝基芳基羧酸反应形成硝基苯甲酰酯而形成，然后可以进行氢化步骤以形成支化多胺。 然后可将得到的支链多胺与另一水凝胶前体反应形成水凝胶。
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