Preparation of hydroxyalkylpiperazinones by reacting a
2,3-dihydroxy-1,4-dioxane with a hydroalkyldiamine
    2.
    发明授权
    Preparation of hydroxyalkylpiperazinones by reacting a 2,3-dihydroxy-1,4-dioxane with a hydroalkyldiamine 失效
    通过2,3-二羟基-1,4-二恶烷与氢烷基二胺反应制备羟烷基哌嗪酮

    公开(公告)号:US4880934A

    公开(公告)日:1989-11-14

    申请号:US279906

    申请日:1988-12-05

    IPC分类号: C07D241/08 C07D243/08

    CPC分类号: C07D243/08 C07D241/08

    摘要: A process for the preparation of 4-(2-hydroxyalkyl)-2-piperazinones and their substituted derivatives comprising reacting an N-hydroxyalkylalkylenediamine, e.g. 2-[(2-aminoethyl)amino]ethanol, or a hydrocarbyl substituted derivative thereof with an .alpha.,.beta.-dicarbonyl compound, e.g. glyoxal, an alkyl-substituted derivative of glyoxal or a glyoxal equivalent. Certain hexahydro-4-(hydroxyalkyl)-2H-1,4-diazepin-2-ones have been made which are new compounds.

    摘要翻译: 一种制备4-(2-羟基烷基)-2-哌嗪酮及其取代衍生物的方法,包括使N-羟烷基亚烷基二胺如 2 - [(2-氨基乙基)氨基]乙醇或其烃基取代的衍生物与α,β-二羰基化合物,例如 乙二醛,乙二醛或乙二醛等价物的烷基取代衍生物。 已经制备了作为新化合物的某些六氢-4-(羟烷基)-2H-1,4-二氮杂-2-酮。

    Preparation of hydroxyalkylpiperazinones by reacting glyoxal with
hydroxyalkyldiamines
    3.
    发明授权
    Preparation of hydroxyalkylpiperazinones by reacting glyoxal with hydroxyalkyldiamines 失效
    乙二醛与羟烷基二胺反应制备羟烷基哌嗪酮

    公开(公告)号:US4814443A

    公开(公告)日:1989-03-21

    申请号:US085428

    申请日:1987-08-13

    IPC分类号: C07D241/08 C07D243/08

    CPC分类号: C07D241/08 C07D243/08

    摘要: A process for the preparation of 4-(2-hydroxyalkyl)-2-piperazinones and their substituted derivatives comprising reacting an N-hydroxyalkylalkylenediamine, e.g.2-[(2-aminoethyl)amino]ethanol, or a hydrocarbyl substituted derivative thereof with an .alpha.,.beta.-dicarbonyl compound, e.g. glyoxal, an alkyl-substituted derivative of glyoxal or a glyoxal equivalent. Certain hexahydro-4-(hydroxyalkyl)-2H-1,4-diazepin-2-ones have been made which are new compounds.

    摘要翻译: 一种制备4-(2-羟基烷基)-2-哌嗪酮及其取代衍生物的方法,包括使N-羟烷基亚烷基二胺例如2 - [(2-氨基乙基)氨基]乙醇或其烃基取代的衍生物与α ,β-二羰基化合物,例如 乙二醛,乙二醛或乙二醛等价物的烷基取代衍生物。 已经制备了作为新化合物的某些六氢-4-(羟烷基)-2H-1,4-二氮杂-2-酮。