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    Tropane derivatives useful in therapy
    4.
    发明授权
    Tropane derivatives useful in therapy 有权
    托烷衍生物可用于治疗

    公开(公告)号：US07368460B2

    公开(公告)日：2008-05-06

    申请号：US10678836

    申请日：2003-10-03

    申请人： Manoussos Perros ,  David Anthony Price ,  Blanda Luzia Christa Stammen ,  Anthony Wood

    发明人： Manoussos Perros ,  David Anthony Price ,  Blanda Luzia Christa Stammen ,  Anthony Wood

    IPC分类号： A01N43/42 ,  A61K31/44

    CPC分类号： C07D451/04 ,  A61K9/2018 ,  A61K31/4196 ,  A61K31/46 ,  A61K2300/00

    摘要： The present invention provides compounds of the formula: wherein R1 is C3-6 cycloalkyl optionally substituted by one or more fluorine atoms, or C1-6 alkyl optionally substituted by one or more fluorine atoms, or C3-6 cycloalkylmethyl optionally ring-substituted by one or more fluorine atoms; and R2 is phenyl optionally substituted by one or more fluorine atoms, to pharmaceutically acceptable salts and solvates thereof, and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such compounds.

    摘要翻译： 本发明提供下式的化合物：其中R 1是任选被一个或多个氟原子取代的C 3-6环烷基，或C 1-6烷基， 任选被一个或多个氟原子取代的C 1 -C 6烷基或任意被一个或多个氟原子环取代的C 3-6环烷基甲基; 和R 2是任选被一个或多个氟原子取代的苯基，其药学上可接受的盐和溶剂合物，以及制备用于制备含有和/ ，这些化合物。

    TROPANE DERIVATIVES USEFUL IN THERAPY
    5.
    发明申请
    TROPANE DERIVATIVES USEFUL IN THERAPY 有权
    TROPANE衍生物有用于治疗

    公开(公告)号：US20080132537A1

    公开(公告)日：2008-06-05

    申请号：US12023334

    申请日：2008-01-31

    申请人： Manoussos PERROS ,  David Anthony Price ,  Blanda Luzia Christa Stammen ,  Anthony Wood

    发明人： Manoussos PERROS ,  David Anthony Price ,  Blanda Luzia Christa Stammen ,  Anthony Wood

    IPC分类号： A61K31/46 ,  A61P31/18 ,  A61P29/00

    CPC分类号： C07D451/04 ,  A61K9/2018 ,  A61K31/4196 ,  A61K31/46 ,  A61K2300/00

    摘要： The present invention provides compounds of the formula: wherein R1 is C3-6 cycloalkyl optionally substituted by one or more fluorine atoms, or C1-6 alkyl optionally substituted by one or more fluorine atoms, or C3-6 cycloalkylmethyl optionally ring-substituted by one or more fluorine atoms; and R2 is phenyl optionally substituted by one or more fluorine atoms, to pharmaceutically acceptable salts and solvates thereof, and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such compounds.

    摘要翻译： 本发明提供下式的化合物：其中R 1是任选被一个或多个氟原子取代的C 3-6环烷基或C 1-6 - 任选被一个或多个氟原子取代的C 1 -C 6烷基或任选被一个或多个氟原子环取代的C 3-6环烷基甲基; 和R 2是任选被一个或多个氟原子取代的苯基，其药学上可接受的盐和溶剂合物，以及制备用于制备含有和/或使用的组合物的组合物的中间体 ，这些化合物。

    Tropane derivatives useful in therapy
    6.
    发明授权
    Tropane derivatives useful in therapy 有权
    托烷衍生物可用于治疗

    公开(公告)号：US06667314B2

    公开(公告)日：2003-12-23

    申请号：US09865950

    申请日：2001-05-25

    申请人： Manoussos Perros ,  David Anthony Price ,  Blanda Luzia Christa Stammen ,  Anthony Wood

    发明人： Manoussos Perros ,  David Anthony Price ,  Blanda Luzia Christa Stammen ,  Anthony Wood

    IPC分类号： A61K3146

    CPC分类号： C07D451/04 ,  A61K9/2018 ,  A61K31/4196 ,  A61K31/46 ,  A61K2300/00

    摘要： The present invention provides compounds of the formula: wherein R1 is C3-6 cycloalkyl optionally substituted by one or more fluorine atoms, or C1-6 alkyl optionally substituted by one or more fluorine atoms, or C3-6 cycloalkylmethyl optionally ring-substituted by one or more fluorine atoms; and R2 is phenyl optionally substituted by one or more fluorine atoms, to pharmaceutically acceptable salts and solvates thereof, and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such compounds.

    摘要翻译： 本发明提供下式的化合物：其中R 1为任选被一个或多个氟原子取代的C 3-6环烷基，或任选被一个或多个氟原子取代的C 1-6烷基，或任选被C 3-6环烷基甲基任选的环 - 被一个或多个氟原子取代; 和R 2是任选被一个或多个氟原子取代的苯基，其药学上可接受的盐和溶剂合物，以及制备用于制备含这些化合物的组合物和用途的中间体的方法。