公开(公告)号：US20040053206A1

公开(公告)日：2004-03-18

申请号：US10456981

申请日：2003-06-06

Applicant: Dyax Corp.

Inventor： Marco Cicardi ,  Luigi Bergamaschini

IPC: A01N001/02

CPC classification number: A01N1/02 ,  A01N1/0226

Abstract: The invention relates to a method for preserving an organ or tissue comprising contacting the organ or tissue with an effective amount of a kallikrein inhibitor and solutions useful for such a method. Also provided is a method for reducing reperfusion injury of an organ during surgery and/or following removal of the organ from a subject comprising placing the organ in an organ storage and preservative solution, wherein the solution comprises a kallikrein inhibitor.

Abstract translation: 本发明涉及一种用于保存器官或组织的方法，包括使器官或组织与有效量的激肽释放酶抑制剂和用于该方法的溶液接触。 还提供了一种减少手术期间和/或从受试者去除器官后器官的再灌注损伤的方法，包括将器官置于器官储存和防腐溶液中，其中该溶液包含激肽释放酶抑制剂。