-
公开(公告)号：US11684669B2
公开(公告)日：2023-06-27
申请号：US17471904
申请日：2021-09-10
发明人： Andreas Meinke , Michael Möhlen , Christoph Reinisch , Robert Schlegl , Christian Taucher , John Campbell , David Novack , Robert S. Janssen , Jürgen Heindl-Wruss
IPC分类号： C12N7/00 , A61K39/215 , A61K39/00
CPC分类号： A61K39/215 , A61K2039/545 , A61K2039/55561
摘要： Described herein are CpG-adjuvanted SARS-CoV-2 vaccines and compositions and methods of producing and administering said vaccines to subjects in need thereof.
-
公开(公告)号：US20230092650A1
公开(公告)日：2023-03-23
申请号：US17802361
申请日：2021-03-01
发明人： John D. Campbell , Robert S. Janssen , David Novack , Christian Taucher , Christoph Reinisch , Andreas Meinke , Michael Möhlen , Robert Schlegl , Jürgen Heindl-Wruss
IPC分类号： A61K39/215 , C12N7/00 , A61P31/14
摘要： The present disclosure relates to immunogenic compositions comprising a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen, and a toll-like receptor 9 (TLR9) agonist, such as an oligonucleotide comprising an unmethylated cytidine-phospho-guano sine (CpG) motif. The immunogenic compositions are suitable for stimulating an immune response against a SARS-CoV-2 in an individual in need thereof.
-
公开(公告)号：US20230038284A1
公开(公告)日：2023-02-09
申请号：US17471904
申请日：2021-09-10
发明人： Andreas Meinke , Michael Möhlen , Christoph Reinisch , Robert Schlegl , Christian Taucher , John Campbell , David Novack , Robert S. Janssen
IPC分类号： A61K39/215
摘要： Described herein are CpG-adjuvanted SARS-CoV-2 vaccines and compositions and methods of producing and administering said vaccines to subjects in need thereof.
-
公开(公告)号：US20240165215A1
公开(公告)日：2024-05-23
申请号：US18344780
申请日：2023-06-29
申请人： Dynavax Technologies Corporation , The Government of the United States, as Represented by the Secretary of the Army
CPC分类号： A61K39/0291 , A61K39/39 , A61P31/04 , A61K2039/545 , A61K2039/55505 , A61K2039/55561
摘要： The present disclosure relates to immunogenic compositions comprising at least one Yersinia pestis (Y. pestis) antigen, an aluminum salt adjuvant, and an oligonucleotide comprising an unmethylated cytidine-phospho-guanosine (CpG) motif. The immunogenic compositions are suitable for stimulating an immune response against Y. pestis in a subject in need thereof. The present disclosure also relates to kits and methods using the immunogenic compositions, or two separate compositions which together comprise the antigen, the aluminum salt adjuvant, and the oligonucleotide.
-
-
-
搜索结果
4 条记录 (耗时 0.016 秒)
