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公开(公告)号：US11684669B2
公开(公告)日：2023-06-27
申请号：US17471904
申请日：2021-09-10
发明人： Andreas Meinke , Michael Möhlen , Christoph Reinisch , Robert Schlegl , Christian Taucher , John Campbell , David Novack , Robert S. Janssen , Jürgen Heindl-Wruss
IPC分类号： C12N7/00 , A61K39/215 , A61K39/00
CPC分类号： A61K39/215 , A61K2039/545 , A61K2039/55561
摘要： Described herein are CpG-adjuvanted SARS-CoV-2 vaccines and compositions and methods of producing and administering said vaccines to subjects in need thereof.
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公开(公告)号：US20230092650A1
公开(公告)日：2023-03-23
申请号：US17802361
申请日：2021-03-01
发明人： John D. Campbell , Robert S. Janssen , David Novack , Christian Taucher , Christoph Reinisch , Andreas Meinke , Michael Möhlen , Robert Schlegl , Jürgen Heindl-Wruss
IPC分类号： A61K39/215 , C12N7/00 , A61P31/14
摘要： The present disclosure relates to immunogenic compositions comprising a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen, and a toll-like receptor 9 (TLR9) agonist, such as an oligonucleotide comprising an unmethylated cytidine-phospho-guano sine (CpG) motif. The immunogenic compositions are suitable for stimulating an immune response against a SARS-CoV-2 in an individual in need thereof.
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公开(公告)号：US20230038284A1
公开(公告)日：2023-02-09
申请号：US17471904
申请日：2021-09-10
发明人： Andreas Meinke , Michael Möhlen , Christoph Reinisch , Robert Schlegl , Christian Taucher , John Campbell , David Novack , Robert S. Janssen
IPC分类号： A61K39/215
摘要： Described herein are CpG-adjuvanted SARS-CoV-2 vaccines and compositions and methods of producing and administering said vaccines to subjects in need thereof.
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公开(公告)号：US20240293531A1
公开(公告)日：2024-09-05
申请号：US17913638
申请日：2021-04-06
申请人： Valneva Austria GmbH
IPC分类号： A61K39/215 , A61K39/00 , A61P31/14 , C12N7/00
CPC分类号： A61K39/215 , A61P31/14 , C12N7/00 , A61K2039/5252 , A61K2039/545 , A61K2039/55 , A61K2039/55505 , A61K2039/55555 , A61K2039/55561 , A61K2039/575 , C12N2770/20034 , C12N2770/20063
摘要： Described herein are SARS-CoV-2 vaccines and compositions and methods of producing and administering said vaccines to subjects in need thereof.
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公开(公告)号：US12018054B2
公开(公告)日：2024-06-25
申请号：US16497178
申请日：2018-04-13
申请人： Valneva Austria GmbH
CPC分类号： C07K14/20 , A61K39/0225 , A61K39/39 , A61P31/04 , A61K2039/55505 , A61K2039/575 , A61K2039/70 , C07K2319/02 , C07K2319/90
摘要： The present invention relates to an immunogenic polypeptide, a nucleic acid encoding the same, a pharmaceutical composition comprising the same and the immunogenic polypeptide, nucleic acid or pharmaceutical composition for use as a medicament, particularly a vaccine, or for use in a method of treating or preventing a Borrelia infection.
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公开(公告)号：US20230295245A1
公开(公告)日：2023-09-21
申请号：US17932226
申请日：2022-09-14
申请人： Valneva Austria GmbH
发明人： Pär Comstedt , Urban Lundberg , Andreas Meinke , Markus Hanner , Wolfgang Schüler , Benjamin Wizel , Christoph Reinisch , Brigitte Grohmann , Robert Schlegl
CPC分类号： C07K14/20 , C07K16/12 , C12P21/02 , A61K39/0225 , A61K39/02 , C12N5/06 , C12N15/70 , C07K16/1207 , C12P21/00 , A61K2039/55505
摘要： The present invention relates to a polypeptide comprising a mutant fragment of an outer surface protein A (OspA), a nucleic acid coding the same, a pharmaceutical composition (particularly for use as a medicament of in a method of treating or preventing a Borrelia infection) comprising the polypeptide and/or the nucleic acid, a method of treating or preventing a Borrelia infection and a method of immunizing a subject.
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公开(公告)号：US11208439B2
公开(公告)日：2021-12-28
申请号：US15906618
申请日：2018-02-27
申请人： Valneva Austria GmbH
发明人： Pär Comstedt , Markus Hanner , Urban Lundberg , Andreas Meinke , Wolfgang Schüler , Benjamin Wizel
IPC分类号： A61K38/00 , C07K14/20 , C07K16/12 , C12P21/02 , A61K39/02 , C12N5/07 , C12N15/70 , C12P21/00 , A61K39/00
摘要： The present invention relates to a polypeptide comprising a mutant fragment of an outer surface protein A (OspA), a nucleic acid coding the same, a pharmaceutical composition (particularly for use as a medicament of in a method of treating or preventing a Borrelia infection) comprising the polypeptide and/or the nucleic acid, a method of treating or preventing a Borrelia infection and a method of immunizing a subject.
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公开(公告)号：US20180327460A1
公开(公告)日：2018-11-15
申请号：US15906618
申请日：2018-02-27
申请人： Valneva Austria GmbH
发明人： Pär Comstedt , Markus Hanner , Urban Lundberg , Andreas Meinke , Wolfgang Schüler , Benjamin Wizel
CPC分类号： C07K14/20 , A61K38/00 , A61K39/02 , A61K39/0225 , A61K2039/55505 , A61K2039/6018 , A61K2039/6031 , C07K16/12 , C07K16/1207 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2319/00 , C12N5/06 , C12N15/70 , C12P21/00 , C12P21/02 , Y02A50/39 , Y02A50/396 , Y02A50/40 , Y02A50/401 , Y02A50/403
摘要： The present invention relates to a polypeptide comprising a mutant fragment of an outer surface protein A (OspA), a nucleic acid coding the same, a pharmaceutical composition (particularly for use as a medicament of in a method of treating or preventing a Borrelia infection) comprising the polypeptide and/or the nucleic acid, a method of treating or preventing a Borrelia infection and a method of immunizing a subject.
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公开(公告)号：US09926343B2
公开(公告)日：2018-03-27
申请号：US15267372
申请日：2016-09-16
申请人： Valneva Austria GmbH
发明人： Pär Comstedt , Markus Hanner , Urban Lundberg , Andreas Meinke , Wolfgang Schüler , Benjamin Wizel
IPC分类号： C07K14/20 , A61K39/02 , C12N5/07 , C12N15/70 , C07K16/12 , C12P21/02 , A61K39/00 , A61K38/00
CPC分类号： C07K14/20 , A61K38/00 , A61K39/02 , A61K39/0225 , A61K2039/55505 , A61K2039/6018 , A61K2039/6031 , C07K16/12 , C07K2319/00 , C12N5/06 , C12N15/70 , C12P21/02 , Y02A50/39 , Y02A50/396 , Y02A50/40 , Y02A50/401 , Y02A50/403
摘要： The present invention relates to a polypeptide comprising a mutant fragment of an outer surface protein A (OspA), a nucleic acid coding the same, a pharmaceutical composition (particularly for use as a medicament of in a method of treating or preventing a Borrelia infection) comprising the polypeptide and/or the nucleic acid, a method of treating or preventing a Borrelia infection and a method of immunizing a subject.
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公开(公告)号：US20170101446A1
公开(公告)日：2017-04-13
申请号：US15272581
申请日：2016-09-22
申请人： Valneva Austria GmbH
发明人： Pär Comstedt , Urban Lundberg , Andreas Meinke , Markus Hanner , Wolfgang Schüler , Benjamin Wizel , Christoph Reinisch , Brigitte Grohmann , Robert Schlegl
摘要： The present invention relates to a polypeptide comprising a mutant fragment of an outer surface protein A (OspA), a nucleic acid coding the same, a pharmaceutical composition (particularly for use as a medicament of in a method of treating or preventing a Borrelia infection) comprising the polypeptide and/or the nucleic acid, a method of treating or preventing a Borrelia infection and a method of immunizing a subject.
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