公开(公告)号：US20230133910A1

公开(公告)日：2023-05-04

申请号：US17907055

申请日：2021-03-29

申请人： EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

发明人： Yi YANG ,  Xianjun CHEN ,  Xin XIE ,  Ni SU

IPC分类号： C12Q1/6876 ,  C12Q1/6816

摘要： The present disclosure relates to an aptamer nucleic acid molecule, a complex containing the aptamer and fluorophore small molecules, a method for detecting intrecellular or extracellular RNA, DNA or other target molecules, as well as a kit containing the aptamer. The aptamer of the present disclosure can specifically bind to fluorophore small molecules, and can significantly improve their fluorescence intensity under light excitation at suitable wavelength.