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公开(公告)号:US10479798B2
公开(公告)日:2019-11-19
申请号:US15523058
申请日:2015-10-30
申请人: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY , SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
发明人: Honglin Li , Hualiang Jiang , Yufang Xu , Jia Li , Zhenjiang Zhao , Jingya Li , Hongling Xu , Shiliang Li
IPC分类号: C07D311/60 , C07D311/92 , C07D405/04 , C07D493/04 , A61K31/352 , A61K31/5377 , C07D221/10 , C07D335/04 , C07D417/04
摘要: The present invention relates to six-membered ring benzo derivatives as a DPP-4 inhibitor and a use thereof. In particular, the present invention relates to a compound as shown in formula I, a pharmaceutical composition containing the compound as shown in formula I and a use of the compound in the preparation of drugs for treating DPP-4 related diseases or inhibiting DPP-4.