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公开(公告)号：US20240115380A1
公开(公告)日：2024-04-11
申请号：US18544266
申请日：2023-12-18
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Mark M. Dehdashtian , Teodoro S. Jimenez
IPC: A61F2/24
CPC classification number: A61F2/2433 , A61F2/2412 , A61F2/2418
Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus via a transaortic approach. The system includes a balloon catheter for delivering a balloon-expandable prosthetic heart valve through an introducer from an approach from outside the patient, through a minimally-invasive opening in the chest cavity through an incision in the aorta, and into the aorta and aortic annulus. The balloon catheter includes a flexible, tapered tip just distal of the balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.
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公开(公告)号：US20200289123A1
公开(公告)日：2020-09-17
申请号：US16886720
申请日：2020-05-28
Applicant: Edwards Lifesciences Corporation
Inventor： Mark M. Dehdashtian , Teodoro S. Jimenez , Nathan Satter , Fabian Daniel Schroeder , Raffaele Mazzei , Jeff Kosmoski , Shahram Zamani , Adam J. Yestrepsky
Abstract: Aortic occlusion and embolic protection devices include radially expandable and collapsible proximal and distal end portions, such as annular self-expanding stents or frames, that are configured to radially expand within an aorta to secure the device within the aorta. The devices can also include a catheter extending axially between the distal end portion and the proximal end portion and a porous covering, or filter, positioned around the catheter and between the proximal end portion and the distal end portion and configured to filter emboli from blood flowing into upper-body arteries. The device can further include a one-way valve positioned at or adjacent to the distal end portion of the device and configured to restrict retrograde blood flow through the device toward the heart.
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公开(公告)号：US20170245992A1
公开(公告)日：2017-08-31
申请号：US15596409
申请日：2017-05-16
Applicant: Edwards Lifesciences Corporation
Inventor： Mark M. Dehdashtian , Jane M. Olin
IPC: A61F2/24
CPC classification number: A61F2/2436 , A61F2/24 , A61F2/2412 , A61F2/2433 , A61F2002/9583 , A61F2220/0016
Abstract: A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating is disclosed. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle. A guidewire is advanced into the left ventricle and through the aortic valve. An introducer is passed over the guidewire and into the left ventricle. A valve delivery device is advanced over the guidewire and through the introducer until a prosthetic heart valve positioned thereon is located within the aortic valve. The prosthetic heart valve is then radially expanded within the aortic valve annulus for replacing the function of the native aortic valve.
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公开(公告)号：US12274616B2
公开(公告)日：2025-04-15
申请号：US17958105
申请日：2022-09-30
Applicant: Edwards Lifesciences Corporation
Inventor： Teodoro S. Jimenez , Walter Lee , Mark M. Dehdashtian , Kristopher J. Yee
Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic valve through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.
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公开(公告)号：US20200229921A1
公开(公告)日：2020-07-23
申请号：US16841100
申请日：2020-04-06
Applicant: Edwards Lifesciences Corporation
Inventor： Walter Lee , Mark M. Dehdashtian , Teodoro S. Jimenez , Gilbert S. Leung , Bryan A. Janish , Michael G. Valdez , Tram Ngoc Nguyen , Timothy C. Ulrich
Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.
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Patent Agency Ranking
公开(公告)号：US20190070000A1
公开(公告)日：2019-03-07
申请号：US16178537
申请日：2018-11-01
Applicant: Edwards Lifesciences Corporation
Inventor： Mark M. Dehdashtian , Teodoro S. Jimenez
IPC: A61F2/24
Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus via a transaortic approach. The system includes a balloon catheter for delivering a balloon-expandable prosthetic heart valve through an introducer from an approach from outside the patient, through a minimally-invasive opening in the chest cavity through an incision in the aorta, and into the aorta and aortic annulus. The balloon catheter includes a flexible, tapered tip just distal of the balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.
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公开(公告)号：US11896485B2
公开(公告)日：2024-02-13
申请号：US16178537
申请日：2018-11-01
Applicant: Edwards Lifesciences Corporation
Inventor： Mark M. Dehdashtian , Teodoro S. Jimenez
IPC: A61F2/24
CPC classification number: A61F2/2433 , A61F2/2412 , A61F2/2418
Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus via a transaortic approach. The system includes a balloon catheter for delivering a balloon-expandable prosthetic heart valve through an introducer from an approach from outside the patient, through a minimally-invasive opening in the chest cavity through an incision in the aorta, and into the aorta and aortic annulus. The balloon catheter includes a flexible, tapered tip just distal of the balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.
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公开(公告)号：US11571216B2
公开(公告)日：2023-02-07
申请号：US16886720
申请日：2020-05-28
Applicant: Edwards Lifesciences Corporation
Inventor： Mark M. Dehdashtian , Teodoro S. Jimenez , Nathan Satter , Fabian Daniel Schroeder , Raffaele Mazzei , Jeff Kosmoski , Shahram Zamani , Adam J. Yestrepsky
Abstract: Aortic occlusion and embolic protection devices include radially expandable and collapsible proximal and distal end portions, such as annular self-expanding stents or frames, that are configured to radially expand within an aorta to secure the device within the aorta. The devices can also include a catheter extending axially between the distal end portion and the proximal end portion and a porous covering, or filter, positioned around the catheter and between the proximal end portion and the distal end portion and configured to filter emboli from blood flowing into upper-body arteries. The device can further include a one-way valve positioned at or adjacent to the distal end portion of the device and configured to restrict retrograde blood flow through the device toward the heart.
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公开(公告)号：US20190290425A1
公开(公告)日：2019-09-26
申请号：US16438345
申请日：2019-06-11
Applicant: Edwards Lifesciences Corporation
Inventor： Mark M. Dehdashtian , Jane M. Olin
IPC: A61F2/24
Abstract: A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating is disclosed. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle. A guidewire is advanced into the left ventricle and through the native aortic valve. An introducer is passed over the guidewire and into the left ventricle. A valve delivery device is advanced over the guidewire and through the introducer until a prosthetic heart valve positioned thereon is located within the native aortic valve. The prosthetic heart valve is then radially expanded within the aortic valve annulus for replacing the function of the native aortic valve.
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公开(公告)号：US20180042722A1
公开(公告)日：2018-02-15
申请号：US15795176
申请日：2017-10-26
Applicant: Edwards Lifesciences Corporation
Inventor： Teodoro S. Jimenez , Mark M. Dehdashtian , Raffaele Mazzei
IPC: A61F2/24
CPC classification number: A61F2/2409 , A61F2/2448 , A61F2/2466 , A61F2220/0091 , A61F2230/0091 , A61F2230/0095
Abstract: A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site. Collapsible devices include devices that can hingedly fold about hinge lines, and devices that can elongate to form substantially spiral forms with reduced diameters.
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