公开(公告)号：US20220032235A1

公开(公告)日：2022-02-03

申请号：US17432122

申请日：2020-02-20

Applicant: EMD Millipore Corporation

Inventor： Kevin Rautio ,  Sean Foley ,  Stephen G. Hunt ,  Bumchul Lee ,  Nathan Landry

IPC: B01D63/08

Abstract: Single-use integral chromatography unit having an inlet and an outlet, and comprising one or more plates or pairs of filter plates interposable between a pair of end plates. In certain embodiments, each of the filter plates comprises a polymeric framework with one or more membranes supported therein. The filter plates and end plates may be assembled to form a substantially fixed, substantially water-tight, integral stack. Fluid entering the unit through a common inlet passes the membrane or membranes of each filter plate substantially contemporaneously prior to exiting the unit through a common outlet (cf, “parallel” flow). The assembly is a modular design, as multiple pairs of plates can be stacked in a suitable holder to form a single chromatography unit.

公开(公告)号：US20220001334A1

公开(公告)日：2022-01-06

申请号：US17292981

申请日：2019-12-05

Applicant: EMD Millipore Corporation

Inventor： Nathan Landry ,  Gregory Straeffer ,  Matthew Natale

IPC: B01D65/00 ,  B01D63/10

Abstract: A spiral wound membrane module, comprising a perforated core having an axially extending internal bore; at least one membrane packet comprising a folded membrane sheet defining a first outer face, a first inner face, a second outer face and a second inner face, the fold of the folded membrane sheet being a leading end of the membrane packet; a feed sheet positioned between the first and second inner faces so as to be sandwiched by the folded membrane sheet; a first permeate screen adjacent the first outer face of the membrane sheet defining a first permeate channel; a second permeate screen adjacent the second outer face of the membrane sheet defining a second permeate channel; and a fluid impermeable support coupled to the leading edge of the membrane packet. Also disclosed is a method of manufacturing the spiral wound membrane module.