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公开(公告)号:US12016910B2
公开(公告)日:2024-06-25
申请号:US17043192
申请日:2019-04-11
申请人: ENTEROME S.A.
CPC分类号: A61K39/001119 , A61K39/00115 , A61K39/001152 , A61K39/001154 , A61P35/00 , A61K2039/55566
摘要: The present invention relates to antigen-based immunotherapy, in particular cancer immunotherapy. In particular, the present invention provides antigenic peptides, which are distinct from, but have amino acid similarity to, fragments of human tumor antigens. The present invention further provides immunogenic compounds, nanoparticles, cells and pharmaceutical compositions comprising such antigenic peptides and nucleic acids encoding such antigenic peptides.
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公开(公告)号:US11478538B2
公开(公告)日:2022-10-25
申请号:US16338955
申请日:2017-10-09
申请人: ENTEROME S.A.
发明人: Laurent Chene , Alban Mathieu , Matthieu Pichaud
摘要: The invention relates to an immunogenic compound comprising an antigenic peptide having amino acid similarity with a tumor antigen, which antigenic peptide is selected in the group consisting of peptides having amino acid similarity with IL13RA2, the said antigenic peptide being selected in the group consisting of sequences described in the specification.
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公开(公告)号:US11712465B2
公开(公告)日:2023-08-01
申请号:US16338954
申请日:2017-10-09
申请人: ENTEROME S.A.
IPC分类号: A61K39/00 , G01N33/574 , G01N33/68 , A61P35/00 , G16B30/00 , A61K39/02 , C07K4/04 , C07K7/00
CPC分类号: A61K39/0011 , A61P35/00 , G01N33/574 , G01N33/6878 , G16B30/00 , A61K39/0208 , C07K4/04 , C07K7/00 , G01N2333/195 , G01N2333/70539
摘要: The present invention relates to cancer immunotherapy, in particular to sequence variants of tumor-related antigenic epitope sequences. Namely, the present invention provides a method for identification of microbiota sequence variants of tumor-related antigenic epitope sequences. Such microbiota sequence variants are useful for the preparation of anticancer medicaments, since they differ from self-antigens and, thus, they may elicit a strong immune response. Accordingly, medicaments comprising microbiota sequence variants, methods of preparing such medicaments and uses of such medicaments are provided.
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公开(公告)号:US12059460B2
公开(公告)日:2024-08-13
申请号:US17929063
申请日:2022-09-01
申请人: ENTEROME S.A.
发明人: Laurent Chene , Alban Mathieu , Matthieu Pichaud
CPC分类号: A61K39/0011 , A61K39/00114 , A61K39/39 , A61P35/00 , A61K2039/5158 , A61K2039/53 , A61K2039/55555 , A61K2039/572 , A61K2039/6031
摘要: The invention relates to an immunogenic compound comprising an antigenic peptide having amino acid similarity with a tumor antigen, which antigenic peptide is selected in the group consisting of peptides having amino acid similarity with IL13RA2, the said antigenic peptide being selected in the group consisting of sequences described in the specification.
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公开(公告)号:US11759508B2
公开(公告)日:2023-09-19
申请号:US17734694
申请日:2022-05-02
申请人: ENTEROME S.A.
CPC分类号: A61K39/001112 , A61K39/001113 , A61K39/001117 , A61K39/001124 , A61K39/001129 , A61P35/00 , A61K2039/55516 , A61K2039/55566
摘要: The present invention relates to antigen-based immunotherapy, in particular cancer immunotherapy. In particular, the present invention provides antigenic peptides, which are distinct from, but have amino acid similarity to, especially share the same core sequence with epitopes of human tumor antigens. The present invention further provides immunogenic compounds, nanoparticles, cells and pharmaceutical compositions comprising such antigenic peptides and nucleic acids encoding such antigenic peptides.
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公开(公告)号:US11478537B2
公开(公告)日:2022-10-25
申请号:US16338953
申请日:2017-10-09
申请人: ENTEROME S.A.
IPC分类号: A61K39/00 , A61P35/00 , A61K39/385 , C07K7/06
摘要: The invention relates to an immunogenic compound comprising an antigenic peptide having amino acid similarity with a tumor antigen, which antigenic peptide is selected in the group consisting of sequences described in the specification.
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