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公开(公告)号：US10058527B2
公开(公告)日：2018-08-28
申请号：US14912916
申请日：2014-08-18
发明人： Jae Wha Kim , Sei Ryang Oh , Kyung Seop Ahn , Ho Bum Kang , Jae Min Shin , Young Eun Ko , Tae Suk Lee , Myung Hwan Kim , Jong Koo Kang , Yong-Hae Han , Ki-Young Sohn
IPC分类号： A61K31/225 , A61K31/231 , A61K31/23 , A61K35/32 , A23L33/10 , A61K31/22
CPC分类号： A61K31/231 , A23L33/10 , A23V2002/00 , A61K31/22 , A61K31/23 , A61K35/32
摘要： The present invention relates to a composition containing a monoacetyldiglyceride compound as an active ingredient, for inhibiting blood cancer or metastasis, and a use thereof. The monoacetyldiglyceride compound according to the present invention has excellent effects of inhibiting the expression of IL-4 and inhibiting the activity of STAT-6, and thereby is capable of overcoming side effects of currently used blood cancer or metastasis inhibiting agents. Also, the monoacetyldiglyceride compound is a non-toxic compound having superior therapeutic effects and thus can be useful as a composition for preventing, treating, or improving blood cancer and metastasis.
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2.发明申请公开(公告)号：US20200330421A1
公开(公告)日：2020-10-22
申请号：US16886280
申请日：2020-05-28
发明人： Jae Wha Kim , Sei-Ryang Oh , Kyung Seop Ahn , Ho Bum Kang , Jae Min Shin , Young Eun Ko , Tae Suk Lee , Myung Hwan Kim , Jong Koo Kang , Yong-Hae Han , Ki Young Sohn
IPC分类号： A61K31/231 , A23L33/10 , A61K35/32 , A61K31/23
摘要： The present invention relates to a composition containing a monoacetyldiglyceride compound as an active ingredient, for inhibiting blood cancer or metastasis, and a use thereof. The monoacetyldiglyceride compound according to the present invention has excellent effects of inhibiting the expression of IL-4 and inhibiting the activity of STAT-6, and thereby is capable of overcoming side effects of currently used blood cancer or metastasis inhibiting agents. Also, the monoacetyldiglyceride compound is a non-toxic compound having superior therapeutic effects and thus can be useful as a composition for preventing, treating, or improving blood cancer and metastasis.
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3.发明申请COMPOSITION CONTAINING MONOACETYLDIACYLGLYCEROL COMPOUND AS ACTIVE INGREDIENT FOR INHIBITING BLOOD CANCER OR METASTASIS 审中-公开含有单一乙酰胆碱酯化合物的组合物作为抑制血液癌或METASTASIS的主动成分公开(公告)号：US20160256428A1
公开(公告)日：2016-09-08
申请号：US14912916
申请日：2014-08-18
发明人： Jae Wha Kim , Sei Ryang Oh , Kyung Seop Ahn , Ho Bum Kang , Jae Min Shin , Young Eun Ko , Tae Suk Lee , Myung Hwan Kim , Jong Koo Kang , Yong-Hae Han , Ki-Young Sohn
IPC分类号： A61K31/231 , A61K35/32
CPC分类号： A61K31/231 , A23L33/10 , A23V2002/00 , A61K31/22 , A61K31/23 , A61K35/32
摘要： The present invention relates to a composition containing a monoacetyldiglyceride compound as an active ingredient, for inhibiting blood cancer or metastasis, and a use thereof. The monoacetyldiglyceride compound according to the present invention has excellent effects of inhibiting the expression of IL-4 and inhibiting the activity of STAT-6, and thereby is capable of overcoming side effects of currently used blood cancer or metastasis inhibiting agents. Also, the monoacetyldiglyceride compound is a non-toxic compound having superior therapeutic effects and thus can be useful as a composition for preventing, treating, or improving blood cancer and metastasis.
摘要翻译： 本发明涉及含有单乙酰甘油二酯化合物作为活性成分的抑制血癌或转移的组合物及其用途。 根据本发明的单乙酰甘油二酯化合物具有抑制IL-4表达和抑制STAT-6活性的优异效果，从而能够克服目前使用的血癌或转移抑制剂的副作用。 此外，单乙酰甘油二酯化合物是具有优异治疗效果的无毒化合物，因此可用作预防，治疗或改善血液癌和转移的组合物。
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公开(公告)号：US10857119B2
公开(公告)日：2020-12-08
申请号：US16045617
申请日：2018-07-25
发明人： Jae Wha Kim , Sei-Ryang Oh , Kyung Seop Ahn , Ho Bum Kang , Jae Min Shin , Young Eun Ko , Tae Suk Lee , Myung Hwan Kim , Jong Koo Kang , Yong-Hae Han , Ki-Young Sohn
IPC分类号： A61K31/231 , A61K31/23 , A23L33/10 , A61K35/32 , A61K31/22
摘要： The present invention relates to a composition containing a monoacetyldiglyceride compound as an active ingredient, for inhibiting blood cancer or metastasis, and a use thereof. The monoacetyldiglyceride compound according to the present invention has excellent effects of inhibiting the expression of IL-4 and inhibiting the activity of STAT-6, and thereby is capable of overcoming side effects of currently used blood cancer or metastasis inhibiting agents. Also, the monoacetyldiglyceride compound is a non-toxic compound having superior therapeutic effects and thus can be useful as a composition for preventing, treating, or improving blood cancer and metastasis.
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