公开(公告)号：US20180228921A1

公开(公告)日：2018-08-16

申请号：US15895414

申请日：2018-02-13

申请人： EXCISION BIOTHERAPEUTICS, INC.

发明人： Kamel Khalili ,  Won-Bin Young

IPC分类号： A61K49/00 ,  A61K38/46 ,  A61K31/7088 ,  A61P31/18

CPC分类号： A61K49/0013 ,  A01K2227/105 ,  A01K2267/0337 ,  A01K2267/0393 ,  A61K31/7088 ,  A61K38/465 ,  A61K48/00 ,  A61K49/0097 ,  A61P31/18 ,  C12N2740/16043 ,  Y02A50/385 ,  Y02A50/387 ,  Y02A50/389 ,  Y02A50/391 ,  Y02A50/393 ,  Y02A50/397 ,  Y02A50/463 ,  Y02A50/467

摘要： A reporter gene that can be administered to an individual such as HIV-BAL-eLuc in order to detect the presence of a virus. A method of detecting the presence of virus in an individual, by administering a reporter gene to the individual, associating the reporter gene with the virus, imaging the individual, and detecting the presence of virus in the individual. A method of determining the efficacy of a treatment for a virus, by administering a reporter gene to the individual receiving treatment for the virus, associating the reporter gene with the virus, imaging the individual, detecting the presence of virus in the individual, and determining if the treatment is effective.