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公开(公告)号：US10278815B2
公开(公告)日：2019-05-07
申请号：US16017465
申请日：2018-06-25
发明人： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo C. Cayabyab , Robert Bowes
摘要： An assembly includes a prosthetic heart valve and a delivery apparatus for implanting the prosthetic heart valve within the native aortic valve of a patient. The prosthetic heart valve has a radially compressible and expandable metallic stent and a flexible valvular structure mounted within the stent. The delivery apparatus has a handle, a first shaft having a proximal end portion and a distal end portion, a second shaft extending co-axially through the first shaft and having a proximal end portion and a distal end portion, the proximal end portions of the first and second shafts extending distally from the handle, a valve cover coupled to the distal end portion of the first shaft, and a nose piece coupled to the distal end portion of the second shaft.
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公开(公告)号：US20140058502A1
公开(公告)日：2014-02-27
申请号：US14066259
申请日：2013-10-29
发明人： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo Cayabyab , Robert Bowes
IPC分类号： A61F2/24
CPC分类号： A61F2/2433 , A61F2/2436 , A61F2/958 , A61F2002/9517 , A61M25/0045 , A61M25/005 , A61M25/0136 , A61M25/0662 , A61M39/0613
摘要： Embodiments of the present disclosure provide a delivery apparatus for delivering a prosthetic heart valve to a native valve site via the human vasculature without the need for a separate introducer sheath. The delivery apparatus is particularly well-suited for advancing a prosthetic valve through the aorta (i.e., in a retrograde approach) for replacing a stenotic aortic valve.
摘要翻译： 本公开的实施例提供了一种用于经由人类脉管系统将假体心脏瓣膜递送至自然瓣膜部位而不需要单独导引鞘的输送装置。 输送装置特别适用于通过主动脉推进人造瓣膜（即逆行方法），以更换狭窄的主动脉瓣。
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公开(公告)号：US20230329864A1
公开(公告)日：2023-10-19
申请号：US18212102
申请日：2023-06-20
发明人： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo C. Cayabyab , Robert Bowes
CPC分类号： A61F2/2433 , A61M25/0136 , A61M25/0662 , A61F2/2436 , A61F2/958
摘要： Assemblies and delivery apparatus for delivering a medical device into a patient's vasculature are disclosed. In some examples, an assembly includes a delivery apparatus and a radially compressible and expandable prosthetic heart valve. The delivery apparatus includes a handle, a first shaft and a second shaft extending from the handle, and a locking mechanism to prevent axial movement of the second shaft relative to first shaft. The second shaft extends coaxially through the first shaft and includes, at a distal end portion thereof, a balloon, one or more radiopaque markers, and the prosthetic valve radially compressed over the balloon. A flared end piece extending from the first shaft covers a proximal portion of the balloon during advancing of the delivery apparatus through a patient's vasculature. The first shaft is retractable relative to the second shaft to expose the balloon from the flared end piece.
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公开(公告)号：US11510779B2
公开(公告)日：2022-11-29
申请号：US16216246
申请日：2018-12-11
发明人： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo C. Cayabyab , Robert Bowes
摘要： Embodiments of the present disclosure provide an introducer device for introducing a medical device into a patient's vasculature. In one embodiment, the introducer device comprises a housing, a distal sheath adapted to be inserted into a patient's vasculature with the housing positioned outside of the patient's vasculature, a hemostatic seal mounted within the housing, and a tube positioned within the housing and movable longitudinally relative to the hemostatic seal between a proximal position and a distal position. In the proximal position, a distal end of the tube is positioned proximal to the hemostatic seal with the hemostatic seal closed. In the distal position, the distal end of the tube extends through the hemostatic seal and permits the medical device to be inserted through the housing and into the patient's vasculature without contacting the hemostatic seal.
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公开(公告)号：US11382743B2
公开(公告)日：2022-07-12
申请号：US16994945
申请日：2020-08-17
发明人： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo C. Cayabyab , Robert Bowes
摘要： Embodiments of the present disclosure provide a delivery apparatus for a prosthetic heart valve. Disclosed steerable catheters can include a handle, a steerable shaft extending from the handle, and a pull wire. The shaft can include a main lumen, an inner polymeric layer surrounding the main lumen, a braided layer surrounding the inner polymeric layer, and an outer polymeric layer surrounding the braided layer, the outer polymeric layer defining a pull wire lumen. The pull wire can extend from the handle and through the pull wire lumen and can have a distal end portion coupled to a distal end portion of the shaft.
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公开(公告)号：US10010418B2
公开(公告)日：2018-07-03
申请号：US15676817
申请日：2017-08-14
发明人： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo Cayabyab , Robert Bowes
CPC分类号： A61F2/2433 , A61F2/2436 , A61F2/958 , A61F2002/9517 , A61M25/0045 , A61M25/005 , A61M25/0136 , A61M25/0662 , A61M39/0613
摘要： An assembly includes a prosthetic heart valve and a delivery apparatus for implanting the prosthetic heart valve within the native aortic valve of a patient. The prosthetic heart valve has a radially compressible and expandable metallic stent and a flexible valvular structure mounted within the stent. The delivery apparatus has a handle, a first shaft having a proximal end portion and a distal end portion, a second shaft extending co-axially through the first shaft and having a proximal end portion and a distal end portion, the proximal end portions of the first and second shafts extending distally from the handle, a valve cover coupled to the distal end portion of the first shaft, and a nose piece coupled to the distal end portion of the second shaft.
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公开(公告)号：US11883285B2
公开(公告)日：2024-01-30
申请号：US17003836
申请日：2020-08-26
发明人： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo C. Cayabyab , Robert Bowes
CPC分类号： A61F2/2433 , A61F2/2436 , A61M25/0136 , A61M25/0662 , A61F2/958 , A61F2/9517 , A61M25/005 , A61M25/0045 , A61M25/0147 , A61M39/0613
摘要： Embodiments of the present disclosure provide an introducer device and methods for introducing a medical device into a patient's vasculature. In one embodiment, a method of using an introducer device including a housing, a hemostatic seal mounted within the housing, and a tube extending into the housing and movable longitudinally relative to the hemostatic seal between a proximal position and a distal position, includes moving the tube to the distal position such that the distal end of the tube extends through the hemostatic seal. The method further includes inserting a distal end portion of the medical device through the tube and into the patient's vasculature without contacting the hemostatic seal.
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公开(公告)号：US20230074408A1
公开(公告)日：2023-03-09
申请号：US17985009
申请日：2022-11-10
发明人： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo C. Cayabyab , Robert Bowes
摘要： A method for replacing a stenotic native aortic valve of a patient can include inserting a delivery apparatus into a femoral artery of the patient, the delivery apparatus having a first shaft extending from the handle, a second shaft disposed around the first shaft, a third shaft extending through the second shaft, and a valve cover coupled to the first shaft. The valve cover can be in a first state housing an entirety of a prosthetic heart valve and retaining the prosthetic heart valve in a radially compressed state during the act of inserting. The method can further include advancing the delivery apparatus through the aorta of the patient to position the valve cover and the prosthetic heart valve within the native aortic valve, and moving the valve cover longitudinally from the first state to a second state in which the entirety of the prosthetic heart valve is uncovered.
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公开(公告)号：US20210030540A1
公开(公告)日：2021-02-04
申请号：US17073076
申请日：2020-10-16
发明人： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo C. Cayabyab , Robert Bowes
摘要： Embodiments of the present disclosure provide an introducer device and method for introducing a delivery apparatus into a patient's vasculature. Disclosed methods can include positioning a sleeve of an introducer sheath in a blood vessel of a patient, the sleeve having a lattice layer with a lumen therethrough, inserting a distal end portion of the delivery apparatus and a prosthetic heart valve into the lumen, and advancing the distal end portion of the delivery apparatus through the lumen from the proximal end to the distal end. The method can then include expanding the lumen from a first diameter smaller to a second diameter at least equal to the diameter of the prosthetic heart valve to allow passage of the prosthetic heart valve through the lumen, and returning the lumen of the sleeve to a diameter smaller than the second diameter after advancing the prosthetic heart valve through the lumen.
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公开(公告)号：US20200375735A1
公开(公告)日：2020-12-03
申请号：US16994945
申请日：2020-08-17
发明人： Philippe Marchand , David M. Taylor , Robert Milich , David J. Evans , Christopher Chia , Ronaldo C. Cayabyab , Robert Bowes
摘要： Embodiments of the present disclosure provide a delivery apparatus for a prosthetic heart valve. Disclosed steerable catheters can include a handle, a steerable shaft extending from the handle, and a pull wire. The shaft can include a main lumen, an inner polymeric layer surrounding the main lumen, a braided layer surrounding the inner polymeric layer, and an outer polymeric layer surrounding the braided layer, the outer polymeric layer defining a pull wire lumen. The pull wire can extend from the handle and through the pull wire lumen and can have a distal end portion coupled to a distal end portion of the shaft.
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