公开(公告)号：US20250152359A1

公开(公告)日：2025-05-15

申请号：US18962021

申请日：2024-11-27

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Sergio Delgado ,  Lauren R. Freschauf ,  Eric Robert Dixon ,  Grant Matthew Stearns ,  Rachel Ann Cooney ,  Rachel Liat David Foreman ,  Alex Philip McCann ,  David M. Taylor

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/04 ,  A61B17/34 ,  A61L27/04

Abstract: In a method of treating an atrioventricular valve, a sealing element is deployed in a native atrioventricular valve of a heart at a position between native atrioventricular valve leaflets to contact the native atrioventricular valve leaflets. The sealing element is controlled by user input to both radially expand and radially reduce the sealing element while at the position between the native atrioventricular valve leaflets. At least one of the native atrioventricular leaflets is secured between an inner anchor member and an outer anchor member to support the sealing element at a desired position between the native atrioventricular valve leaflets.

公开(公告)号：US12263085B2

公开(公告)日：2025-04-01

申请号：US18221990

申请日：2023-07-14

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： David M. Taylor

IPC: A61F2/24 ,  A61M25/01

Abstract: A method of implanting a balloon expandable prosthetic valve within a native aortic valve includes introducing a delivery system into a femoral artery of a patient, the delivery system comprising an outer sleeve and a shaft extending through a lumen of the outer sleeve. A distal end portion of the shaft is positioned distal to a distal end of a steerable distal end portion of the outer sleeve. A prosthetic valve is crimped over a balloon disposed along the distal end portion of the shaft. The delivery system further comprises a first radiopaque marker inside the balloon and positioned adjacent a proximal end of the prosthetic valve and a second radiopaque marker inside the balloon and positioned adjacent a distal end of the prosthetic valve. The method also includes identifying a location of the prosthetic valve by monitoring the first and second radiopaque markers inside the balloon under fluoroscopy.

公开(公告)号：US20240335287A1

公开(公告)日：2024-10-10

申请号：US18745063

申请日：2024-06-17

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Mark Chau ,  Travis Zenyo Oba ,  Sam Shafigh ,  Jean-Pierre Michel Rabbah ,  David M. Taylor ,  Philippe Marchand ,  Madison Paige Kukura ,  Cristobal R. Hernandez ,  Nancy Hoang Khuu ,  Florian Georg Deuschl ,  Biswa P. Das ,  Andrew Charles May ,  Bhumica A. Amin

IPC: A61F2/24

CPC classification number: A61F2/2463 ,  A61F2/2466 ,  A61F2220/0008 ,  A61F2230/0008

Abstract: Systems and methods are disclosed for use with a valve of a heart. An implant (100) includes a wing (120); a flexible frame (124); and a pair of anchor receivers (150). A pair of shafts (660) are transluminally advanced through a catheter (40), while the shafts are each engaged with a respective anchor receiver (150), to deploy the implant out of the catheter such that the wing extends away from the anchor receivers and over a first leaflet of the valve and toward an opposing leaflet of the valve, with a contact face (122) of the wing facing the first leaflet. A pair of drivers (70) secure the implant using a pair of anchors (30) to anchor each anchor receiver to tissue at respective sites of the heart. Other implementations are also described.

公开(公告)号：US20240299163A1

公开(公告)日：2024-09-12

申请号：US18658829

申请日：2024-05-08

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Taylor Jacob Scheinblum ,  Hieu Minh Luong ,  David Robert Landon ,  Siddharth Vad ,  Ramon Aguilar, JR. ,  David M. Taylor ,  Jesse Robert Edwards ,  Brandon Sina Dehdashtian

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2/2436 ,  A61F2220/0008

Abstract: Devices, systems, and methods relate to implants, such as prosthetic valves for replacing native heart valves. Delivery systems for delivering the implants to an implantation site are also disclosed herein. A prosthetic valve may include a valve body supporting a plurality of prosthetic valve leaflets and one or more adjustable anchors coupled to the valve body for anchoring the prosthetic valve to leaflets of a native heart valve, wherein at least one of the adjustable anchors is axially slidable relative to the valve body for conforming to the native anatomy of the native heart valve.

公开(公告)号：US11850153B2

公开(公告)日：2023-12-26

申请号：US17178162

申请日：2021-02-17

Applicant: Edwards Lifesciences Corporation

Inventor： Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/04 ,  A61B17/34 ,  A61L27/04

CPC classification number: A61F2/246 ,  A61B17/00 ,  A61B17/00234 ,  A61B17/0469 ,  A61B17/3468 ,  A61F2/24 ,  A61F2/243 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2442 ,  A61F2/2445 ,  A61F2/2457 ,  A61L27/04 ,  A61B17/0057 ,  A61B17/0401 ,  A61B2017/00243 ,  A61B2017/00557 ,  A61B2017/00783 ,  A61B2017/00867 ,  A61B2017/0464 ,  A61F2/2427 ,  A61F2/2454 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2210/009 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/0041 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/0004 ,  A61F2230/0008 ,  A61F2230/0013 ,  A61F2230/0045 ,  A61F2230/0069 ,  A61F2230/0093 ,  A61F2240/00 ,  A61F2250/006 ,  A61F2250/0036 ,  A61F2250/0069

Abstract: A valve repair devices and systems for repairing a native valve of a patient include a spacer, a pair of paddles, and a pair of moveable clasp arms. The pair of moveable clasp arms are disposed between the pair of paddles and the spacer. The moveable clasp arms are configured to attach to leaflets of a heart valve. The spacer, the pair of paddles, and the moveable clasp arms are configured such that, when attached to the leaflets, the moveable clasp arms are located between the spacer and first portions of the leaflet, while second portions of the leaflet engage the spacer.

公开(公告)号：US11793642B2

公开(公告)日：2023-10-24

申请号：US16522600

申请日：2019-07-25

Applicant: Edwards Lifesciences Corporation

Inventor： Mark Chau ,  David M. Taylor ,  Alexander J. Siegel ,  Christopher J. Olson ,  Sergio Delgado ,  Alexander H. Cooper ,  Lauren R. Freschauf ,  Asher L. Metchik ,  Matthew T. Winston ,  Cristobal R. Hernandez ,  Emil Karapetian ,  Bao Khuu ,  Eric Robert Dixon

IPC: A61F2/24

CPC classification number: A61F2/246 ,  A61F2/2454 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2220/0016 ,  A61F2310/00023

Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. The spacer body can be made from braided, self-expandable metallic thread. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.

公开(公告)号：US20230190460A1

公开(公告)日：2023-06-22

申请号：US18166797

申请日：2023-02-09

Applicant: Edwards Lifesciences Corporation

Inventor： David M. Taylor ,  Alexander J. Siegel ,  Thomas V. Doherty ,  Christopher J. Olson ,  Yoon Hee Kwon

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2463 ,  A61F2/2412 ,  A61L27/18

Abstract: Embodiments of the present disclosure include an implantable assembly for a native heart valve that includes a prosthetic heart valve and a braided support structure. The prosthetic valve includes a frame and prosthetic leaflets. The braided support structure has an inner braided layer and an outer braided layer. The outer braided layer is disposed over the inner braided layer. The outer braided layer is less porous to blood than the inner braided layer. The braided support structure defines a plurality of arms that are angularly spaced around the prosthetic heart valve such that each arm extends radially outwardly from the prosthetic heart valve. Other embodiments are also described.

公开(公告)号：US11602431B2

公开(公告)日：2023-03-14

申请号：US16171202

申请日：2018-10-25

Applicant: Edwards Lifesciences Corporation

Inventor： Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor ,  Asher L. Metchik ,  Matthew T. Winston ,  Gregory Scott Tyler, II ,  Lauren R. Freschauf ,  Alexander J. Siegel

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/04 ,  A61B17/34 ,  A61L27/04

Abstract: An exemplary valve repair device for repairing a native valve of a patient includes a coaption element, a pair of paddles, and barb portions. The barb portions extend directly from at least one of the coaption element and the pair of paddles.

公开(公告)号：US10849754B2

公开(公告)日：2020-12-01

申请号：US16130853

申请日：2018-09-13

Applicant: Edwards Lifesciences Corporation

Inventor： Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/04 ,  A61B17/34 ,  A61L27/04

Abstract: An exemplary implantable prosthetic device has a coaption element and a pair of paddles. The coaption element has a first end portion and a second end portion. The pair of paddles is connected to the second end portion of the coaption element. The coaption element narrows as the copation element extends from the first end portion to the second end portion. The paddles are movable between an open position and a closed position. The paddles are configured to attach to the native valve of the patient.

公开(公告)号：US20200246136A1

公开(公告)日：2020-08-06

申请号：US16842837

申请日：2020-04-08

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Devin H. Marr ,  Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor ,  Asher L. Metchik ,  Matthew T. Winston

IPC: A61F2/24 ,  A61B17/128 ,  A61B17/122

Abstract: A delivery system includes an elongate shaft, a handle, a first clasp control member, and a second clasp control member. The handle is connected to a proximal portion of the elongate shaft. The first and second clasp control members each extend into a distal portion of the elongate shaft, through at least a portion of the elongate shaft, out of the proximal portion of the elongate shaft, and through the handle. The first and second clasp control members have paths that include a first parallel portion in the elongate shaft where the first clasp control member and the second clasp control member are parallel, and a diverging portion that is proximal to the first parallel portion where the first clasp control member diverges from the second clasp control member.