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1.发明授权Stable extract from Hypericum perforatum L., method for the production thereof and its use as a topical medicament 有权来自金丝桃的稳定提取物，其生产方法及其作为局部药物的用途公开(公告)号：US07166310B2
公开(公告)日：2007-01-23
申请号：US10451714
申请日：2001-12-21
申请人： Egon Koch , Clemens Erdelmeier , Joachim Herrmann
发明人： Egon Koch , Clemens Erdelmeier , Joachim Herrmann
CPC分类号： A61K36/38 , C07C45/78 , C07C49/743
摘要： The invention relates to an improved and stable (i.e. color-stable and, optionally, stable with regard to its hyperforin content) extract from the overground parts of Hypericum perforatum L., to a method for the preparation thereof, and to pharmaceutical preparations and topical medicaments that contain this extract; in particular, gels for treating skin and mucous membrane irritations and disorders such as acne, atopic dermatitis, neuro-dermatitis, psoriasis, stomatitis, herpes zoster, herpes labialis (lip herpes), warts, varicella (chicken-pox), sores, burns and other bacterial and viral skin and mucous membrane infections and skin disorders that are accompanied by cell proliferation and inflammation.
摘要翻译： 本发明涉及从贯叶连翘的地上部分提取物，其制备方法以及药物制剂和局部施用的改进和稳定（即，其稳定性，并且可选地稳定于其高福林含量） 含有此提取物的药物; 特别是用于治疗皮肤和粘膜刺激的凝胶和诸如痤疮，特应性皮炎，神经性皮炎，牛皮癣，口腔炎，带状疱疹，唇疱疹（唇疱疹），疣，水痘（鸡痘），疮，烧伤的疾病 以及伴随细胞增殖和炎症的其它细菌和病毒皮肤和粘膜感染和皮肤病症。
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2.发明申请Method for preparing ginkgo extracts having a low content of 4'-O-methyl pyridoxine and/or biflavones 审中-公开制备低含量4'-O-甲基吡哆醇和/或双黄酮的银杏提取物的方法公开(公告)号：US20060251746A1
公开(公告)日：2006-11-09
申请号：US11416924
申请日：2006-05-02
申请人： Clemens Erdelmeier , Hermann Hauer , Egon Koch , Friedrich Lang
发明人： Clemens Erdelmeier , Hermann Hauer , Egon Koch , Friedrich Lang
IPC分类号： A61K36/16
摘要： The present invention relates to an improved multi-step method for preparing an extract from ginkgo biloba having a reduced content of 4′-O-methyl pyridoxine and/or biflavones, wherein the depletion is carried out by filtration over an adsorber resin and/or an ion exchanger and the substances to be removed are retained on the resin. The invention further relates to an extract from ginkgo biloba having a reduced content of 4′-O-methyl pyridoxine and/or biflavones, which is obtainable by the method according to the present invention, as well as to its use.
摘要翻译： 本发明涉及一种用于制备具有降低的4'-O-甲基吡哆醇和/或双黄酮含量的银杏提取物的改进的多步法，其中通过在吸附树脂上过滤和/或 离子交换剂和待除去的物质保留在树脂上。 本发明还涉及通过本发明的方法获得的具有降低的4'-O-甲基吡哆醛和/或双黄酮含量的银杏提取物及其用途。
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公开(公告)号：US20050042318A1
公开(公告)日：2005-02-24
申请号：US10486390
申请日：2002-08-08
申请人： Clemens Erdelmeier , Egon Koch
发明人： Clemens Erdelmeier , Egon Koch
IPC分类号： C07D311/60 , A61K31/121 , A61K31/352 , A61K36/00 , A61K36/185 , A61P9/00 , A61P13/08 , A61P15/00 , A61P19/10 , A61P25/28 , B01D11/00 , B01D11/02 , C12C3/08 , C12C3/10 , A61K35/78
CPC分类号： C12C9/025 , A61K36/185 , C12C3/10
摘要： Novel extracts from hop with an increased content of prenylated chalcones and flavones, methods for producing the same, pharmaceutical preparations comprising such extracts of hop and use of these extracts of hop for the prophylaxis and treatment of pathological conditions caused by oestrogen deficiency or by dysregulations to sex-hormone-related metabolism are described.
摘要翻译： 具有增加异戊二烯酸化的查尔酮和黄酮含量的新型提取物，其制备方法，包含这种啤酒花提取物的药物制剂，并使用这些啤酒花提取物预防和治疗由雌激素缺乏引起的病理状况或通过调节失调 描述了与性激素相关的代谢。
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4.发明授权公开(公告)号：US07381429B2
公开(公告)日：2008-06-03
申请号：US10312613
申请日：2001-06-29
申请人： Clemens Erdelmeier , Hermann Jaggy , Egon Koch
发明人： Clemens Erdelmeier , Hermann Jaggy , Egon Koch
IPC分类号： A01N65/00
CPC分类号： A61K36/48
摘要： The invention relates to extracts from Sophora species, to a method for producing the same and to their use in the prophylaxis and therapy of pathological conditions that are caused by estrogen deficiency or by other hormonal dysregulations.
摘要翻译： 本发明涉及来自苦参素的提取物，其生产方法及其在预防和治疗由雌激素缺乏或其它激素失调引起的病理状况中的用途。
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5.发明申请Method for preparing a Ginkgo extract having a reduced content of 4'-O-methyl pyridoxine and/or biflavones 审中-公开制备具有降低的4'-O-甲基吡哆醇和/或双黄酮含量的银杏提取物的方法公开(公告)号：US20060251745A1
公开(公告)日：2006-11-09
申请号：US11416878
申请日：2006-05-02
IPC分类号： A61K36/16
CPC分类号： A61K36/16 , A23L33/105 , A23V2002/00 , A23V2200/322 , A23V2250/2122 , A23V2200/326
摘要： The present invention relates to a method for preparing an extract from Ginkgo biloba having a reduced content of 4′-O-methyl pyridoxine and/or biflavones compared to the original extract. The invention further relates to extracts from Ginkgo biloba having a reduced content of 4′-O-methyl pyridoxine and/or biflavones compared to the original extract, which is obtainable by the method according to the present invention, as well as to their use.
摘要翻译： 制备具有降低的4'-O-甲基吡哆醛和/或双黄酮含量的银杏的提取物包括（a）在溶剂中制备银杏提取物溶液; （b）将溶液施加到吸附树脂上并从吸附树脂中洗脱纯化的提取物; 和/或（c）将溶液施加到酸性离子交换剂上并从离子交换剂洗脱纯化的提取物; 并且任选地（d）将提取液浓缩并干燥到干提取物中，其中步骤（b）和（c）可以以相反的顺序进行。 与原始提取物相比，制备具有降低的4'-O-甲基吡哆醇和/或双黄酮含量的银杏的提取物包括：（a）在溶剂中制备银杏提取物溶液; （b）将溶液施加到吸附树脂上，并使用溶剂从吸附树脂中洗脱纯化的提取物，其中双黄酮保留在吸附树脂上; 和/或（c）将溶液施加到酸性离子交换剂上，并使用溶剂从离子交换器中洗脱纯化的提取物，其中4'-O-甲基吡哆醛保留在离子交换剂上; 和（d）任选地将提取液浓缩并干燥到干提取物中，其中步骤（b）和（c）可以以相反的顺序进行。 与原始提取物相比，具有降低的4'-O-甲基吡哆醛和/或双黄酮含量的银杏提取物的独立权利要求。 - 活动：灵巧。 - 行动机制：没有给出。
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6.发明授权Method for preparing ginkgo extracts having a low content of 4′-O-methyl pyridoxine and/or biflavones 有权制备低含量4'-O-甲基吡哆醇和/或双黄酮的银杏提取物的方法公开(公告)号：US08642099B2
公开(公告)日：2014-02-04
申请号：US12217803
申请日：2008-07-09
申请人： Clemens Erdelmeier , Hermann Hauer , Egon Koch , Friedrich Lang
发明人： Clemens Erdelmeier , Hermann Hauer , Egon Koch , Friedrich Lang
IPC分类号： A61K35/16
摘要： The present invention relates to an improved multi-step method for preparing an extract from ginkgo biloba having a reduced content of 4′-O-methyl pyridoxine and/or biflavones, wherein the depletion is carried out by filtration over an adsorber resin and/or an ion exchanger and the substances to be removed are retained on the resin. The invention further relates to an extract from ginkgo biloba having a reduced content of 4′-O-methyl pyridoxine and/or biflavones, which is obtainable by the method according to the present invention, as well as to its use.
摘要翻译： 本发明涉及一种用于制备具有降低的4'-O-甲基吡哆醇和/或双黄酮含量的银杏提取物的改进的多步法，其中通过在吸附树脂上过滤和/或 离子交换剂和待除去的物质保留在树脂上。 本发明还涉及通过本发明的方法获得的具有降低的4'-O-甲基吡哆醛和/或双黄酮含量的银杏提取物及其用途。
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7.发明申请Method for preparing ginkgo extracts having a low content of 4'-O-methyl pyridoxine and/or biflavones 有权制备低含量4'-O-甲基吡哆醇和/或双黄酮的银杏提取物的方法公开(公告)号：US20080286391A1
公开(公告)日：2008-11-20
申请号：US12217803
申请日：2008-07-09
申请人： Clemens Erdelmeier , Hermann Hauer , Egon Koch , Friedrich Lang
发明人： Clemens Erdelmeier , Hermann Hauer , Egon Koch , Friedrich Lang
摘要： The present invention relates to an improved multi-step method for preparing an extract from ginkgo biloba having a reduced content of 4′-O-methyl pyridoxine and/or biflavones, wherein the depletion is carried out by filtration over an adsorber resin and/or an ion exchanger and the substances to be removed are retained on the resin. The invention further relates to an extract from ginkgo biloba having a reduced content of 4′-O-methyl pyridoxine and/or biflavones, which is obtainable by the method according to the present invention, as well as to its use.
摘要翻译： 本发明涉及一种用于制备具有降低的4'-O-甲基吡哆醇和/或双黄酮含量的银杏提取物的改进的多步法，其中通过在吸附树脂上过滤和/或 离子交换剂和待除去的物质保留在树脂上。 本发明还涉及通过本发明的方法获得的具有降低的4'-O-甲基吡哆醛和/或双黄酮含量的银杏提取物及其用途。
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8.发明申请Extracts from the Bark of Corynanthe Species and Use Thereof as Well as Medicaments, Dietetic Food Products and Pharmaceutical Preparations Containing Said Extracts 审中-公开Corynanthe物种及其用途的皮肤提取物以及含有所述提取物的药物，饮食食品和药物制剂公开(公告)号：US20090142428A1
公开(公告)日：2009-06-04
申请号：US12084745
申请日：2006-11-07
申请人： Egon Koch , Hermann Hauer
发明人： Egon Koch , Hermann Hauer
CPC分类号： A61K36/74
摘要： The present invention relates to extracts from the bark of corynanthe species, in particular corynanthe pachyceras as well as to their use for the therapy and prophylaxis of diseases of the lower urinary tract, sexual disorders, lipid metabolism disorders, cardiovascular diseases and acute and chronic pain conditions. The present invention further relates to medicaments, dietetic food products and pharmaceutical preparations containing these extracts.
摘要翻译： 本发明涉及corynanthe物种的树皮，特别是corynanthe pachyceras的提取物，以及它们用于治疗和预防下尿路疾病，性障碍，脂质代谢紊乱，心血管疾病和急性和慢性疼痛的用途 条件。 本发明还涉及含有这些提取物的药物，饮食食品和药物制剂。
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公开(公告)号：US20080020068A1
公开(公告)日：2008-01-24
申请号：US11631393
申请日：2005-06-30
申请人： Stefan Germer , Hermann Hauer , Egon Koch , Karl Schotz
发明人： Stefan Germer , Hermann Hauer , Egon Koch , Karl Schotz
IPC分类号： C07D311/08 , A61K31/352 , A61K36/185
CPC分类号： C07D311/16 , A23L33/105 , A61K31/352 , C07D311/14 , C07D311/18
摘要： The present invention relates to the use of trisubstituted benzopyranones for the treatment or propylaxis of pathological conditions associated with oxidative stress and/or inflammatory reactions as well as to novel trisubstituted benzopyranones and the physiologically acceptable salts thereof. The present invention further relates to plant extracts, medicaments, dietetic food products and pharmaceutical preparations containing these compounds.
摘要翻译： 本发明涉及三取代苯并吡喃酮与氧化应激和/或炎症反应相关的病理状况的治疗或丙型肝炎的用途，以及新的三取代苯并吡喃酮及其生理上可接受的盐。 本发明还涉及植物提取物，药物，饮食食品和含有这些化合物的药物制剂。
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10.发明授权Harpagoside-enriched extract from harpagophytum procumbens and processes for producing same 有权来自harpagophytum procumbens的富含Harpagoside的提取物及其生产方法公开(公告)号：US06280737B1
公开(公告)日：2001-08-28
申请号：US09155043
申请日：1999-02-22
申请人： Karl-Heinz Stumpf , Hermann Jaggy , Rainer Oschmann , Egon Koch , Thomas Simmet
发明人： Karl-Heinz Stumpf , Hermann Jaggy , Rainer Oschmann , Egon Koch , Thomas Simmet
IPC分类号： A01N6500
CPC分类号： A61K36/185
摘要： The disclosure relates to extracts from Harpagophytum procumbens with a high harpagoside content, to processes for producing them, such extracts containing no components capable of stimulating the synthesis of thromboxane B2 and cysteinylleucotrienes, and to pharmaceutical compositions containing such extracts.
摘要翻译： 本公开涉及具有高harpagoside含量的Harpagophytum procumbens的提取物，其制备方法，不含能够刺激血栓烷B2和半胱氨酰白三烯的合成的成分的提取物，以及含有这些提取物的药物组合物。
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