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公开(公告)号：US20190038919A1
公开(公告)日：2019-02-07
申请号：US16075125
申请日：2016-10-21
申请人： Elekta LTD.
CPC分类号： A61N5/1049 , A61N5/1039 , A61N5/1045 , A61N5/1064 , A61N5/1067 , A61N5/1068 , A61N5/107 , A61N5/1077 , A61N2005/1055 , G01R33/4808 , G06T7/246 , G06T7/254 , G06T11/003 , G06T2207/10016 , G06T2207/10076 , G06T2207/10081 , G06T2207/10088 , G06T2207/30096
摘要： Systems and methods for managing motions of an anatomical region of interest of a patient during image-guided radiotherapy are disclosed. An exemplary system may include an image acquisition device, a radiotherapy device, and a processor device. The processor device may be configured to determine a primary plane of motion of the anatomical region of interest and determine a plurality of 2D slices parallel to the primary plane. The plurality of 2D slices may define a 3D volume substantially enclosing the anatomical region of interest. The processor device may also be configured to control the image acquisition device to acquire a plurality of 2D images based on the plurality of 2D slices and determine a motion of the anatomical region of interest based on at least a subset of the acquired plurality of 2D images. The processor device may be further configured to control radiation delivery based on the determined motion.
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公开(公告)号：US20150375013A1
公开(公告)日：2015-12-31
申请号：US14702037
申请日：2015-05-01
申请人： Elekta, LTD
摘要： Various implementations of the invention provide techniques and supporting systems that facilitate real-time or near-real-time ultrasound tracking for the purpose of calculating changes in anatomical features during a medical procedure. More specifically, anatomical features within a patient undergoing a medical procedure are tracked by obtaining temporally-distinct three dimensional ultrasound images that include the feature of interest and obtaining a targeted subset of ultrasound images focused on the feature. Based on the targeted subset of ultrasound images, a displacement of the feature is determined and image parameters used to obtain the targeted subset of ultrasound images are adjusted based on the displacement. This results in a time-based sequence of three dimensional images and targeted ultrasound images of the feature that identify changes in the position, size, location, and/or shape of the feature.
摘要翻译： 本发明的各种实现提供了便于实时或近实时超声跟踪的技术和支持系统，以便在医疗过程期间计算解剖特征的变化。 更具体地，通过获得包括感兴趣特征的时间上不同的三维超声图像并获得集中在该特征上的超声图像的目标子集，跟踪经历医疗过程的患者内的解剖特征。 基于超声图像的目标子集，确定特征的位移，并且基于位移来调整用于获得超声图像的目标子集的图像参数。 这导致基于时间的三维图像序列和特征的目标超声图像，其识别特征的位置，大小，位置和/或形状的变化。
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公开(公告)号：US20240249451A1
公开(公告)日：2024-07-25
申请号：US18157504
申请日：2023-01-20
申请人： Elekta LTD.
IPC分类号： G06T11/00
CPC分类号： G06T11/005 , G06T2210/41 , G06T2211/40
摘要： Systems and methods are disclosed for image processing of cone beam computed tomography (CBCT) image data, in connection with radiotherapy planning and treatments. Example operations for training a regression model for data processing include: obtaining a reference medical image of an anatomical area of a human patient; generating a set of CBCT projections from the reference medical image at each of a plurality of projection viewpoints in a CBCT projection space; generating a set of simulated scatter data to represent effects of scatter from CBCT imaging in each respective projection in the set of CBCT projections; and training the regression model using the set of CBCT projections and the set of simulated scatter data. Further operations for use of the trained regression model, and inferring scatter or scatter-corrected projections from the trained regression model, are disclosed.
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公开(公告)号：US20240245363A1
公开(公告)日：2024-07-25
申请号：US18157524
申请日：2023-01-20
申请人： Elekta LTD.
CPC分类号： A61B6/03 , A61B6/4085 , G06T11/005
摘要： Systems and methods are disclosed for image processing of cone beam computed tomography (CBCT) image data, in connection with radiotherapy planning and treatments. Example operations for training of a predictive regression model include: obtaining a reference medical image of an anatomical area (e.g., from a reference CT image); generating variation images that provide variation in representations of the anatomical area (e.g., from deformation or geometric transformation); identifying projection viewpoints (e.g., from projection capture angles in a CBCT projection space) for each of the plurality of variation images; generating, at each of the projection viewpoints, a set of CBCT projections and a corresponding set of simulated aspects of the CBCT projections; training an algorithm in the regression model, using the corresponding sets of the CBCT projections and the simulated aspects of the CBCT projections. Corresponding operations for the use of the regression model, including in radiotherapy treatments, are also disclosed.
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公开(公告)号：US11602646B2
公开(公告)日：2023-03-14
申请号：US17443895
申请日：2021-07-28
申请人： Elekta LTD.
IPC分类号： A61N5/10 , G06T7/33 , G16H40/63 , G16H20/40 , G16H30/20 , G16H30/40 , G16H50/20 , G06T7/20 , G06T7/246 , A61B6/02 , A61B90/00
摘要： Systems and methods are provided for registering images. The systems and methods perform operations comprising: receiving, at a first time point in a given radiation session, a first imaging slice corresponding to a first plane; encoding the first imaging slice to a lower dimensional representation; applying a trained machine learning model to the encoded first imaging slice to estimate an encoded version of a second imaging slice corresponding to a second plane at the first time point to provide a pair of imaging slices for the first time point; simultaneously spatially registering the pair of imaging slices to a volumetric image, received prior to the given radiation session, comprising a time-varying object to calculate displacement of the object; and generating an updated therapy protocol to control delivery of a therapy beam based on the calculated displacement of the object.
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公开(公告)号：US20210361974A1
公开(公告)日：2021-11-25
申请号：US17443895
申请日：2021-07-28
申请人： Elekta LTD.
IPC分类号： A61N5/10 , G06T7/33 , G16H40/63 , G16H20/40 , G16H30/20 , G16H30/40 , G16H50/20 , G06T7/20 , G06T7/246
摘要： Systems and methods are provided for registering images. The systems and methods perform operations comprising: receiving, at a first time point in a given radiation session, a first imaging slice corresponding to a first plane; encoding the first imaging slice to a lower dimensional representation; applying a trained machine learning model to the encoded first imaging slice to estimate an encoded version of a second imaging slice corresponding to a second plane at the first time point to provide a pair of imaging slices for the first time point; simultaneously spatially registering the pair of imaging slices to a volumetric image, received prior to the given radiation session, comprising a time-varying object to calculate displacement of the object; and generating an updated therapy protocol to control delivery of a therapy beam based on the calculated displacement of the object.
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公开(公告)号：US20210046329A1
公开(公告)日：2021-02-18
申请号：US16824276
申请日：2020-03-19
申请人： Elekta LTD.
摘要： Systems and methods are provided for registering images. The systems and methods perform operations comprising: receiving, at a first time point during a given radiation session, a first imaging slice comprising an object, the first imaging slice corresponding to a first plane; accessing, at the first time point during the given radiation session, a composite imaging slice corresponding to the first plane, the composite imaging slice being generated using a plurality of imaging slices obtained prior to the first time point; spatially registering the first imaging slice and the composite imaging slice; determining movement of the object using the spatially registered first imaging slice and the composite imaging slice; and generating an updated therapy protocol to control delivery of a therapy beam based on the determined movement.
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8.发明公开公开(公告)号：US20240245932A1
公开(公告)日：2024-07-25
申请号：US18157531
申请日：2023-01-20
申请人： Elekta LTD.
CPC分类号： A61N5/1039 , A61B6/5282 , G06T11/005 , A61N2005/1041 , G06T2210/41 , G06T2211/40
摘要： Systems and methods are disclosed for processing of cone beam computed tomography (CBCT) image data, in connection with radiotherapy planning and treatments. Example operations for a radiotherapy workflow include: obtaining a plurality of newly captured CBCT projections that provide imaging of an anatomical area corresponding to an area for radiotherapy treatment; reconstructing a quantitative CBCT image from the plurality of newly captured CBCT projections; identifying anatomical changes of the human patient based on comparing a representation of the anatomical area in the quantitative CBCT image with a representation of the anatomical area in a planning image; and modifying a treatment plan for a radiotherapy workflow based on the anatomical changes, with the treatment plan providing dose calculations for the anatomical area. Further operations for training and use of a regression model to correct CBCT projections and perform additional imaging and radiotherapy data processing operations are disclosed.
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公开(公告)号：US20230285776A1
公开(公告)日：2023-09-14
申请号：US18180491
申请日：2023-03-08
申请人： Elekta LTD.
发明人： Martin Emile Lachaine , Tony Falco
IPC分类号： A61N5/10
CPC分类号： A61N5/1038 , A61N5/1049 , A61N5/1067
摘要： A reference radiotherapy treatment plan having a plurality of control points, such as a sequence of gantry angles, aperture leaf positions, and intensity weights, can be adapted during the radiotherapy treatment session. Treatment imaging data of a patient may be obtained during the radiotherapy treatment session and one or more parameters may be determined using the treatment imaging data. Then, a current radiotherapy treatment plan may be generated based on the parameter(s). The reference radiotherapy treatment plan for the radiotherapy treatment session may be modified during the radiotherapy treatment session by updating one of the plurality of control points of the reference radiotherapy treatment plan with a control point of a current radiotherapy treatment plan, which may compensate for patient deformations during the delivery of radiotherapy treatment, or intrafraction patient deformations and thereby improve the delivery accuracy and efficacy of radiation doses to a patient undergoing radiotherapy treatment.
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公开(公告)号：US11040221B2
公开(公告)日：2021-06-22
申请号：US16824276
申请日：2020-03-19
申请人： Elekta LTD.
IPC分类号： A61B6/00 , A61N5/10 , G06T7/33 , G16H40/63 , G16H20/40 , G16H30/20 , G16H30/40 , G16H50/20 , G06T7/20 , G06T7/246 , A61B6/02 , A61B90/00
摘要： Systems and methods are provided for registering images. The systems and methods perform operations comprising: receiving, at a first time point during a given radiation session, a first imaging slice comprising an object, the first imaging slice corresponding to a first plane; accessing, at the first time point during the given radiation session, a composite imaging slice corresponding to the first plane, the composite imaging slice being generated using a plurality of imaging slices obtained prior to the first time point; spatially registering the first imaging slice and the composite imaging slice; determining movement of the object using the spatially registered first imaging slice and the composite imaging slice; and generating an updated therapy protocol to control delivery of a therapy beam based on the determined movement.
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