公开(公告)号：US11192914B2

公开(公告)日：2021-12-07

申请号：US16097382

申请日：2017-04-28

申请人： Emory University

发明人： Gregory Bluemling ,  Abel De La Rosa ,  George Painter ,  Damien Kuiper ,  Alexander Kolykhalov

IPC分类号： C07H19/06 ,  A61K45/06 ,  C07H19/10 ,  C07H19/12 ,  C07H19/14 ,  C07H19/20 ,  C07H19/11 ,  C07H19/213 ,  A61P31/14 ,  A61K31/706 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076 ,  C07H19/16

摘要： This disclosure relates to nucleotide and nucleoside therapeutic compositions and uses in treating infectious diseases, viral infections, and cancer, where the nucleotide or nucleoside is defined by Formula I below,

公开(公告)号：US20230062181A1

公开(公告)日：2023-03-02

申请号：US17494258

申请日：2021-10-05

申请人： Emory University

发明人： Gregory Bluemling ,  Abel de la Rosa ,  George Painter ,  Damien Kuiper ,  Alexander Kolykhalov

IPC分类号： C07H19/06 ,  A61K45/06 ,  C07H19/10 ,  C07H19/12 ,  C07H19/14 ,  C07H19/20 ,  C07H19/11 ,  C07H19/213 ,  A61P31/14 ,  A61K31/706 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076 ,  C07H19/16

摘要： This disclosure relates to nucleotide and nucleoside therapeutic compounds and uses in treating infectious diseases viral infections, and cancer, where the base of the nucleotide or nucleoside contains at least one thiol, thione or thioether.