公开(公告)号：US20210252033A1

公开(公告)日：2021-08-19

申请号：US17170172

申请日：2021-02-08

Applicant: Emory University

Inventor： George R. PAINTER ,  Gregory R. BLUEMLING ,  Michael C. NATCHUS ,  Shuli MAO ,  Jose MARENGO ,  Michael W. HAGER ,  David PERRYMAN

IPC: A61K31/7068 ,  A61M11/00 ,  A61K9/00 ,  C07H19/06 ,  C07H19/10 ,  A61P31/14 ,  A61K31/52 ,  A61K31/522 ,  A61K31/675 ,  A61K31/341 ,  A61K31/7076 ,  A61K31/404 ,  A61K31/4406 ,  A61K31/403 ,  A61K31/513 ,  A61K31/4178 ,  A61K31/34 ,  A61K31/496 ,  A61K31/536 ,  A61K31/4965 ,  A61K31/665 ,  A61K45/06

Abstract: This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of human coronavirus 2019-nCoV.

公开(公告)号：US20250064844A1

公开(公告)日：2025-02-27

申请号：US18940253

申请日：2024-11-07

Applicant: Emory University

Inventor： George R. PAINTER ,  Gregory R. BLUEMLING ,  Michael G. NATCHUS ,  Shuli MAO ,  Jose MARENGO ,  Michael W. HAGER ,  David PERRYMAN

IPC: A61K31/7068 ,  A61K9/00 ,  A61K31/34 ,  A61K31/341 ,  A61K31/403 ,  A61K31/404 ,  A61K31/4178 ,  A61K31/4406 ,  A61K31/496 ,  A61K31/4965 ,  A61K31/513 ,  A61K31/52 ,  A61K31/522 ,  A61K31/536 ,  A61K31/665 ,  A61K31/675 ,  A61K31/7076 ,  A61K45/06 ,  A61M11/00 ,  A61P31/14 ,  C07H19/06 ,  C07H19/10

Abstract: This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of human coronavirus 2019-nCoV.