公开(公告)号：US20190060322A1

公开(公告)日：2019-02-28

申请号：US16120702

申请日：2018-09-04

Applicant: Epizyme, Inc.

Inventor： Kevin Wayne KUNTZ ,  John Emmerson CAMPBELL ,  Masashi SEKI ,  Syuji SHIROTORI ,  Wataru ITANO ,  Wanjun ZHENG

IPC: A61K31/5377 ,  C07D405/12 ,  C07D401/12 ,  A61K31/4545 ,  C07D405/14 ,  A61K31/5375 ,  C07D213/64 ,  A61K31/4412

Abstract: The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.