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公开(公告)号:US07919617B2
公开(公告)日:2011-04-05
申请号:US12637712
申请日:2009-12-14
申请人: Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G. J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang
发明人: Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G. J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang
IPC分类号: C07D265/30 , A61K31/5377
CPC分类号: A61K31/416 , C07D207/40 , C07D231/12 , C07D231/40 , C07D239/47 , C07D249/12 , C07D253/075 , C07D295/088 , C07D403/12 , C07D471/04 , C07D487/04 , Y02A50/401 , Y02A50/409 , Y02A50/411
摘要: The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
摘要翻译: 本发明提供可用作细胞因子抑制剂的低分子量化合物及其组合物。 特别地,本发明的化合物可用作抗炎剂。 还提供了制备这些试剂的方法及其在预防或治疗由细胞因子如关节炎介导的病症中的用途。
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公开(公告)号:US07897599B2
公开(公告)日:2011-03-01
申请号:US12637714
申请日:2009-12-14
申请人: Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G. J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang
发明人: Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G. J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang
IPC分类号: A61K31/535 , C07D265/30
CPC分类号: A61K31/416 , C07D207/40 , C07D231/12 , C07D231/40 , C07D239/47 , C07D249/12 , C07D253/075 , C07D295/088 , C07D403/12 , C07D471/04 , C07D487/04 , Y02A50/401 , Y02A50/409 , Y02A50/411
摘要: The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
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公开(公告)号:US07749999B2
公开(公告)日:2010-07-06
申请号:US10939324
申请日:2004-09-10
申请人: Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G. J. Delaet , Justin Ernst , Antonio Garrido Montalban , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang , Jeffrey Kahl , Christopher Larson
发明人: Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G. J. Delaet , Justin Ernst , Antonio Garrido Montalban , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang , Jeffrey Kahl , Christopher Larson
IPC分类号: A61K31/535 , C07D265/30
CPC分类号: A61K31/416 , C07D207/40 , C07D231/12 , C07D231/40 , C07D239/47 , C07D249/12 , C07D253/075 , C07D295/088 , C07D403/12 , C07D471/04 , C07D487/04 , Y02A50/401 , Y02A50/409 , Y02A50/411
摘要: The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
摘要翻译: 本发明提供可用作细胞因子抑制剂的低分子量化合物及其组合物。 特别地,本发明的化合物可用作抗炎剂。 还提供了制备这些试剂的方法及其在预防或治疗由细胞因子如关节炎介导的病症中的用途。
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公开(公告)号:US20100093735A1
公开(公告)日:2010-04-15
申请号:US12637714
申请日:2009-12-14
申请人: Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G.J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang
发明人: Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G.J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhinjun Wang
IPC分类号: A61K31/535 , C07D295/155
CPC分类号: A61K31/416 , C07D207/40 , C07D231/12 , C07D231/40 , C07D239/47 , C07D249/12 , C07D253/075 , C07D295/088 , C07D403/12 , C07D471/04 , C07D487/04 , Y02A50/401 , Y02A50/409 , Y02A50/411
摘要: The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
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