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公开(公告)号:US07029876B2
公开(公告)日:2006-04-18
申请号:US10080866
申请日:2002-02-22
CPC分类号: A61K39/0258 , C07K14/245 , C12N15/70 , C12N15/71 , C12P21/02 , Y02A50/474
摘要: Vectors for producing polypeptides heterologous to prokaryotes are described comprising, along with the polypeptide-encoding nucleic acid, anti-termination nucleic acid that inhibits intragenic transcription termination with a non-lambda promoter therefor and/or nucleic acid encoding a GreA or GreB protein and a promoter therefor. Also described are processes for producing a heterologous polypeptide in prokaryotic host cells utilizing such elements to improve the quality and/or quantity of heterologous polypeptide produced.